JPS55124758A - Indole derivative and medical composition - Google Patents

Indole derivative and medical composition

Info

Publication number
JPS55124758A
JPS55124758A JP3083480A JP3083480A JPS55124758A JP S55124758 A JPS55124758 A JP S55124758A JP 3083480 A JP3083480 A JP 3083480A JP 3083480 A JP3083480 A JP 3083480A JP S55124758 A JPS55124758 A JP S55124758A
Authority
JP
Japan
Prior art keywords
medical composition
indole derivative
compounds
indole
alkylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3083480A
Other languages
English (en)
Inventor
Furunausu Rudorufu
Gurisu Geruharuto
Gureru Uorufugangu
Zauteru Roberuto
Aizere Berunharuto
Kaubitsushiyu Nikorausu
Ruperehito Etsukuharuto
Keeringu Yohahimu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of JPS55124758A publication Critical patent/JPS55124758A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Power Steering Mechanism (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP3083480A 1979-03-13 1980-03-11 Indole derivative and medical composition Pending JPS55124758A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792909779 DE2909779A1 (de) 1979-03-13 1979-03-13 Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
JPS55124758A true JPS55124758A (en) 1980-09-26

Family

ID=6065240

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3083480A Pending JPS55124758A (en) 1979-03-13 1980-03-11 Indole derivative and medical composition

Country Status (21)

Country Link
US (1) US4343811A (ja)
EP (1) EP0015523B1 (ja)
JP (1) JPS55124758A (ja)
AT (1) ATE1642T1 (ja)
AU (1) AU5636880A (ja)
CA (1) CA1142519A (ja)
CS (1) CS208800B2 (ja)
DD (1) DD149804A5 (ja)
DE (2) DE2909779A1 (ja)
ES (3) ES488446A1 (ja)
FI (1) FI800770A (ja)
GR (1) GR75241B (ja)
HU (1) HU180126B (ja)
IL (1) IL59598A0 (ja)
NO (1) NO800709L (ja)
NZ (1) NZ193111A (ja)
PL (1) PL222634A1 (ja)
PT (1) PT70921B (ja)
SU (1) SU1028247A3 (ja)
YU (1) YU68180A (ja)
ZA (1) ZA801441B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3165998D1 (de) * 1980-06-18 1984-10-18 May & Baker Ltd Indole and indoline derivatives
DE3232968A1 (de) * 1981-09-10 1983-06-09 Degussa Ag, 6000 Frankfurt Neue 2-(hydroxy-phenyl)-indole und verfahren zu deren herstellung
US4543360A (en) * 1981-09-10 1985-09-24 Degussa Aktiengesellschaft 2-(Hydroxy-phenyl)-indoles and process for their production
GB2111050B (en) * 1981-11-19 1985-09-11 Ciba Geigy Ag N-substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4759923A (en) * 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
DE69728688T2 (de) 1996-11-19 2004-08-19 Amgen Inc., Thousand Oaks Aryl und heteroaryl substituierte kondensierte pyrrole als entzündunghemmende mittel
US6103733A (en) * 1998-09-09 2000-08-15 Bachmann; Kenneth A. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
JP2008507518A (ja) 2004-07-22 2008-03-13 ピーティーシー セラピューティクス,インコーポレーテッド C型肝炎を治療するためのチエノピリジン
DE102006053064A1 (de) * 2006-11-08 2008-05-21 Universität Potsdam Verfahren zur Herstellung aromatischer Diazoniumsalze

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237361A1 (de) * 1972-07-29 1974-02-14 Boehringer Mannheim Gmbh (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin

Also Published As

Publication number Publication date
ZA801441B (en) 1981-11-25
IL59598A0 (en) 1980-06-30
FI800770A (fi) 1980-09-14
DD149804A5 (de) 1981-07-29
ATE1642T1 (de) 1982-10-15
PT70921A (de) 1980-04-01
PL222634A1 (ja) 1980-12-01
PT70921B (de) 1981-06-24
ES8101047A1 (es) 1980-12-01
ES488446A1 (es) 1980-10-01
DE3060932D1 (en) 1982-11-18
ES490380A0 (es) 1980-12-01
NO800709L (no) 1980-09-15
CS208800B2 (en) 1981-09-15
ES490379A0 (es) 1980-12-01
NZ193111A (en) 1983-04-12
EP0015523B1 (de) 1982-10-13
US4343811A (en) 1982-08-10
CA1142519A (en) 1983-03-08
GR75241B (ja) 1984-07-13
DE2909779A1 (de) 1980-09-18
SU1028247A3 (ru) 1983-07-07
AU5636880A (en) 1980-09-18
YU68180A (en) 1983-04-30
ES8101048A1 (es) 1980-12-01
HU180126B (en) 1983-02-28
EP0015523A1 (de) 1980-09-17

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