CS202550B2 - Method of preparing novel derivatives of 1-/benzazolylalkyl/piperidine - Google Patents
Method of preparing novel derivatives of 1-/benzazolylalkyl/piperidine Download PDFInfo
- Publication number
- CS202550B2 CS202550B2 CS764688A CS468876A CS202550B2 CS 202550 B2 CS202550 B2 CS 202550B2 CS 764688 A CS764688 A CS 764688A CS 468876 A CS468876 A CS 468876A CS 202550 B2 CS202550 B2 CS 202550B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- parts
- formula
- dihydro
- hydrogen
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Otolaryngology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59779375A | 1975-07-21 | 1975-07-21 | |
| US05/687,139 US4066772A (en) | 1975-07-21 | 1976-05-17 | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
| KR7601697A KR810000334B1 (ko) | 1975-07-21 | 1976-07-12 | 1-(벤즈 아조릴알킬) 피페리딘 유도체의 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS202550B2 true CS202550B2 (en) | 1981-01-30 |
Family
ID=27348142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS764688A CS202550B2 (en) | 1975-07-21 | 1976-07-16 | Method of preparing novel derivatives of 1-/benzazolylalkyl/piperidine |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS5217475A (xx) |
| AT (1) | AT364358B (xx) |
| AU (1) | AU511027B2 (xx) |
| BG (1) | BG26526A3 (xx) |
| CA (1) | CA1085852A (xx) |
| CH (1) | CH623820A5 (xx) |
| CS (1) | CS202550B2 (xx) |
| DE (1) | DE2632870A1 (xx) |
| DK (1) | DK154950C (xx) |
| ES (3) | ES449740A1 (xx) |
| FI (1) | FI62667C (xx) |
| GB (1) | GB1542514A (xx) |
| HK (1) | HK14180A (xx) |
| IE (1) | IE43496B1 (xx) |
| IT (1) | IT1062614B (xx) |
| KE (1) | KE3215A (xx) |
| LU (1) | LU75354A1 (xx) |
| MY (1) | MY8100017A (xx) |
| NL (1) | NL187442C (xx) |
| NZ (1) | NZ181256A (xx) |
| PH (1) | PH13710A (xx) |
| PT (1) | PT65387B (xx) |
| RO (1) | RO70566A (xx) |
| SE (2) | SE426490B (xx) |
| YU (1) | YU39969B (xx) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4501749A (en) * | 1983-10-31 | 1985-02-26 | Merck & Co., Inc. | Peripherally selective dopamine antagonists in the treatment of ocular hypertension |
| JPS6248684A (ja) * | 1985-08-26 | 1987-03-03 | Sumitomo Chem Co Ltd | 新規なヨ−ドブチロフエノン誘導体およびその製造法 |
| JPS62251313A (ja) * | 1986-04-25 | 1987-11-02 | 信越ポリマー株式会社 | 結束装置 |
| FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
| US6355659B1 (en) | 1994-07-29 | 2002-03-12 | Laboratorios Del Dr. Esteve, S.A. | 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same |
| JO2785B1 (en) * | 2003-05-27 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinazoline derivatives |
| UA83881C2 (xx) | 2003-12-18 | 2008-08-26 | Янссен Фармацевтика Н.В. | Піридо- та піримідопіримідинові похідні як антипроліферативні агенти$пиридо- и пиримидопиримидиновые производные как антипролиферативные агенты |
| NI200700147A (es) | 2004-12-08 | 2019-05-10 | Janssen Pharmaceutica Nv | Derivados de quinazolina inhibidores de cinasas dirigidos a multip |
| DK2044084T3 (en) | 2006-07-13 | 2016-05-09 | Janssen Pharmaceutica Nv | MTKI-quinazoline derivatives |
| EP1997805A1 (en) * | 2007-06-01 | 2008-12-03 | Commissariat à l'Energie Atomique | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans |
| DK2185562T3 (en) | 2007-07-27 | 2016-02-22 | Janssen Pharmaceutica Nv | PYRROLOPYRIMIDINES SUITABLE FOR TREATING PROLIFERATIVE DISEASES |
| BRPI0815327A2 (pt) | 2007-08-31 | 2015-12-15 | Purdue Pharma Lp | "compostos de piperidina do tipo quinoxalina substituída e os usos destes" |
| US9090618B2 (en) | 2012-12-27 | 2015-07-28 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
| EA035515B1 (ru) * | 2016-02-04 | 2020-06-29 | Синдом Фарма, Инк. | Композиции на основе дейтерированного домперидона и способы терапии расстройств |
| US11364226B2 (en) | 2017-06-30 | 2022-06-21 | Cinrx Pharma, Llc | Deuterated domperidone compositions, methods, and preparation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE633495A (xx) * | 1962-06-13 | |||
| BE633914A (xx) * | 1962-06-22 | |||
| US3629267A (en) * | 1968-10-28 | 1971-12-21 | Smith Kline French Lab | Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione |
| AU4698672A (en) * | 1972-09-22 | 1972-11-09 | Ciba-Geigy Ag | Azacycloaliphatic compounds, process for their manufacture and compositions containing them |
| FR2218100A1 (en) * | 1973-02-20 | 1974-09-13 | Janssen Pharmaceutica Nv | Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones |
| US3989707A (en) * | 1974-06-21 | 1976-11-02 | Janssen Pharmaceutica N.V. | Benzimidazolinone derivatives |
-
1976
- 1976-06-23 NZ NZ181256A patent/NZ181256A/xx unknown
- 1976-06-30 GB GB7627242A patent/GB1542514A/en not_active Expired
- 1976-07-07 CA CA256,450A patent/CA1085852A/en not_active Expired
- 1976-07-07 RO RO7686860A patent/RO70566A/ro unknown
- 1976-07-08 PH PH18663A patent/PH13710A/en unknown
- 1976-07-09 LU LU75354A patent/LU75354A1/xx unknown
- 1976-07-09 ES ES449740A patent/ES449740A1/es not_active Expired
- 1976-07-16 AU AU15964/76A patent/AU511027B2/en not_active Expired
- 1976-07-16 CS CS764688A patent/CS202550B2/cs unknown
- 1976-07-19 IT IT50499/76A patent/IT1062614B/it active
- 1976-07-19 JP JP51085216A patent/JPS5217475A/ja active Granted
- 1976-07-20 FI FI762086A patent/FI62667C/fi not_active IP Right Cessation
- 1976-07-20 SE SE7608265A patent/SE426490B/xx not_active IP Right Cessation
- 1976-07-20 DK DK327576A patent/DK154950C/da not_active IP Right Cessation
- 1976-07-20 BG BG033791A patent/BG26526A3/xx unknown
- 1976-07-20 AT AT0534776A patent/AT364358B/de not_active IP Right Cessation
- 1976-07-20 NL NLAANVRAGE7608023,A patent/NL187442C/xx not_active IP Right Cessation
- 1976-07-20 IE IE1602/76A patent/IE43496B1/en not_active IP Right Cessation
- 1976-07-20 CH CH929176A patent/CH623820A5/de not_active IP Right Cessation
- 1976-07-20 PT PT65387A patent/PT65387B/pt unknown
- 1976-07-21 DE DE19762632870 patent/DE2632870A1/de active Granted
- 1976-07-21 YU YU1794/76A patent/YU39969B/xx unknown
-
1977
- 1977-08-16 ES ES461631A patent/ES461631A1/es not_active Expired
- 1977-08-16 ES ES461630A patent/ES461630A1/es not_active Expired
-
1980
- 1980-03-20 HK HK141/80A patent/HK14180A/xx unknown
- 1980-12-11 SE SE8008713A patent/SE435621B/sv not_active IP Right Cessation
-
1981
- 1981-12-30 MY MY17/81A patent/MY8100017A/xx unknown
-
1982
- 1982-05-21 KE KE3215A patent/KE3215A/xx unknown
Also Published As
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