SE8008713L - 1-(bensazolylalkyl)piperidiner - Google Patents
1-(bensazolylalkyl)piperidinerInfo
- Publication number
- SE8008713L SE8008713L SE8008713A SE8008713A SE8008713L SE 8008713 L SE8008713 L SE 8008713L SE 8008713 A SE8008713 A SE 8008713A SE 8008713 A SE8008713 A SE 8008713A SE 8008713 L SE8008713 L SE 8008713L
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- lower alkyl
- compound
- van
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Claims (2)
1. (I-c) il van i B2 betecknar iiiiC(0)-, -NH-C ' l'- eller -NCH-, - 0th, on a Onskas,111,maceutiskt ggbara syraadditionssalt fram- stalles an produkterna fin stegen (1-a) till (I-c). ringslutes med ett lampligt cykliseringsmedel enligt kanda metoder for framstallning av en farening med formeln N3 -y—N N-(Cliz)m-LH-(C1-12.).-N\_.! gruppen -N A utgOres av en grupp med formeln 0 -R4 -N R R6 van i R4 betecknar vate eller lagalkyl; och och 6 var fbr sig betecknar vate, halo, lagalkyl eller trifluorometyl; kanneteckoat av att a) en fOrening med formeln 3 B van i 31 bar samma'betydelse eon B men ej -NH-C(S)-, och X Sr en lamp-hg reaktiv esterfunktion harledd fran motsvarande alkohol, bringas att reagera med en fOrening med formeln ett lampligt organiskt losningsmedel, rdrframstgllning av en fore-fling med formeln RI 3 BN -(C14 )NA
2. rn (1-a ) •
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59779375A | 1975-07-21 | 1975-07-21 | |
US05/687,139 US4066772A (en) | 1975-07-21 | 1976-05-17 | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
KR7601697A KR810000334B1 (ko) | 1975-07-21 | 1976-07-12 | 1-(벤즈 아조릴알킬) 피페리딘 유도체의 제조방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8008713L true SE8008713L (sv) | 1980-12-11 |
SE435621B SE435621B (sv) | 1984-10-08 |
Family
ID=27348142
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7608265A SE426490B (sv) | 1975-07-21 | 1976-07-20 | Analogiforfarande for framstellning av 1-(bensazolylalkyl)piperidiner |
SE8008713A SE435621B (sv) | 1975-07-21 | 1980-12-11 | Analogiforfarande for framstellning av 1-(bensimidazolylalkyl)piperidiner |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7608265A SE426490B (sv) | 1975-07-21 | 1976-07-20 | Analogiforfarande for framstellning av 1-(bensazolylalkyl)piperidiner |
Country Status (25)
Country | Link |
---|---|
JP (1) | JPS5217475A (sv) |
AT (1) | AT364358B (sv) |
AU (1) | AU511027B2 (sv) |
BG (1) | BG26526A3 (sv) |
CA (1) | CA1085852A (sv) |
CH (1) | CH623820A5 (sv) |
CS (1) | CS202550B2 (sv) |
DE (1) | DE2632870A1 (sv) |
DK (1) | DK154950C (sv) |
ES (3) | ES449740A1 (sv) |
FI (1) | FI62667C (sv) |
GB (1) | GB1542514A (sv) |
HK (1) | HK14180A (sv) |
IE (1) | IE43496B1 (sv) |
IT (1) | IT1062614B (sv) |
KE (1) | KE3215A (sv) |
LU (1) | LU75354A1 (sv) |
MY (1) | MY8100017A (sv) |
NL (1) | NL187442C (sv) |
NZ (1) | NZ181256A (sv) |
PH (1) | PH13710A (sv) |
PT (1) | PT65387B (sv) |
RO (1) | RO70566A (sv) |
SE (2) | SE426490B (sv) |
YU (1) | YU39969B (sv) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4501749A (en) * | 1983-10-31 | 1985-02-26 | Merck & Co., Inc. | Peripherally selective dopamine antagonists in the treatment of ocular hypertension |
JPS6248684A (ja) * | 1985-08-26 | 1987-03-03 | Sumitomo Chem Co Ltd | 新規なヨ−ドブチロフエノン誘導体およびその製造法 |
JPS62251313A (ja) * | 1986-04-25 | 1987-11-02 | 信越ポリマー株式会社 | 結束装置 |
FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
US6355659B1 (en) | 1994-07-29 | 2002-03-12 | Laboratorios Del Dr. Esteve, S.A. | 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same |
JO2785B1 (en) * | 2003-05-27 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinazoline derivatives |
DE602004012891T2 (de) | 2003-12-18 | 2009-04-09 | Janssen Pharmaceutica N.V. | Pyrido- und pyrimidopyrimidinderivate als anti-proliferative mittel |
NI200700147A (es) | 2004-12-08 | 2019-05-10 | Janssen Pharmaceutica Nv | Derivados de quinazolina inhibidores de cinasas dirigidos a multip |
BRPI0714211B8 (pt) | 2006-07-13 | 2021-05-25 | Janssen Pharmaceutica Nv | derivados de mtki quinazolina, sua utilização e composição farmacêutica que os compreende |
EP1997805A1 (en) * | 2007-06-01 | 2008-12-03 | Commissariat à l'Energie Atomique | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans |
JP5536647B2 (ja) | 2007-07-27 | 2014-07-02 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ピロロピリミジン |
ES2593706T3 (es) | 2007-08-31 | 2016-12-12 | Purdue Pharma Lp | Compuestos de piperidina, de tipo quinoxalina sustituida, y usos de los mismos |
US9090618B2 (en) | 2012-12-27 | 2015-07-28 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
CN113995755A (zh) * | 2016-02-04 | 2022-02-01 | 辛多美制药有限公司 | 氘代多潘立酮组合物和用于治疗病症的方法 |
US11364226B2 (en) | 2017-06-30 | 2022-06-21 | Cinrx Pharma, Llc | Deuterated domperidone compositions, methods, and preparation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE633495A (sv) * | 1962-06-13 | |||
BE633914A (sv) * | 1962-06-22 | |||
US3629267A (en) * | 1968-10-28 | 1971-12-21 | Smith Kline French Lab | Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione |
AU4698672A (en) * | 1972-09-22 | 1972-11-09 | Ciba-Geigy Ag | Azacycloaliphatic compounds, process for their manufacture and compositions containing them |
FR2218100A1 (en) * | 1973-02-20 | 1974-09-13 | Janssen Pharmaceutica Nv | Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones |
US3989707A (en) * | 1974-06-21 | 1976-11-02 | Janssen Pharmaceutica N.V. | Benzimidazolinone derivatives |
-
1976
- 1976-06-23 NZ NZ181256A patent/NZ181256A/xx unknown
- 1976-06-30 GB GB7627242A patent/GB1542514A/en not_active Expired
- 1976-07-07 RO RO7686860A patent/RO70566A/ro unknown
- 1976-07-07 CA CA256,450A patent/CA1085852A/en not_active Expired
- 1976-07-08 PH PH18663A patent/PH13710A/en unknown
- 1976-07-09 ES ES449740A patent/ES449740A1/es not_active Expired
- 1976-07-09 LU LU75354A patent/LU75354A1/xx unknown
- 1976-07-16 AU AU15964/76A patent/AU511027B2/en not_active Expired
- 1976-07-16 CS CS764688A patent/CS202550B2/cs unknown
- 1976-07-19 JP JP51085216A patent/JPS5217475A/ja active Granted
- 1976-07-19 IT IT50499/76A patent/IT1062614B/it active
- 1976-07-20 AT AT0534776A patent/AT364358B/de not_active IP Right Cessation
- 1976-07-20 SE SE7608265A patent/SE426490B/sv not_active IP Right Cessation
- 1976-07-20 BG BG7633791A patent/BG26526A3/xx unknown
- 1976-07-20 PT PT65387A patent/PT65387B/pt unknown
- 1976-07-20 IE IE1602/76A patent/IE43496B1/en not_active IP Right Cessation
- 1976-07-20 NL NLAANVRAGE7608023,A patent/NL187442C/xx not_active IP Right Cessation
- 1976-07-20 CH CH929176A patent/CH623820A5/de not_active IP Right Cessation
- 1976-07-20 DK DK327576A patent/DK154950C/da not_active IP Right Cessation
- 1976-07-20 FI FI762086A patent/FI62667C/fi not_active IP Right Cessation
- 1976-07-21 DE DE19762632870 patent/DE2632870A1/de active Granted
- 1976-07-21 YU YU1794/76A patent/YU39969B/xx unknown
-
1977
- 1977-08-16 ES ES461630A patent/ES461630A1/es not_active Expired
- 1977-08-16 ES ES461631A patent/ES461631A1/es not_active Expired
-
1980
- 1980-03-20 HK HK141/80A patent/HK14180A/xx unknown
- 1980-12-11 SE SE8008713A patent/SE435621B/sv not_active IP Right Cessation
-
1981
- 1981-12-30 MY MY17/81A patent/MY8100017A/xx unknown
-
1982
- 1982-05-21 KE KE3215A patent/KE3215A/xx unknown
Also Published As
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Legal Events
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NUG | Patent has lapsed |
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