ES256994A1 - Procedimiento para la preparaciën de derivados de dibenzocicloheptano terapeuticamente activos - Google Patents

Procedimiento para la preparaciën de derivados de dibenzocicloheptano terapeuticamente activos

Info

Publication number
ES256994A1
ES256994A1 ES0256994A ES256994A ES256994A1 ES 256994 A1 ES256994 A1 ES 256994A1 ES 0256994 A ES0256994 A ES 0256994A ES 256994 A ES256994 A ES 256994A ES 256994 A1 ES256994 A1 ES 256994A1
Authority
ES
Spain
Prior art keywords
compound
chloride
nr3r4
carbon atoms
saturated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0256994A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Pharmaceutische Fabrieken NV
Original Assignee
Koninklijke Pharmaceutische Fabrieken NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Pharmaceutische Fabrieken NV filed Critical Koninklijke Pharmaceutische Fabrieken NV
Publication of ES256994A1 publication Critical patent/ES256994A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para la preparación de derivados de dibenzocicloheptano terapéuticamente activoscaracterizado por el hecho de que se sintetizan por métidos conocidos para la preparación de compuestos análogoscompuestos que tienen la fórmula general **(Ver fórmula)** en la cual X es un grupo -CH2-CH2 o un grupo -CH=CH R1 y R2 representan hidrógenoun átomo de halógeno o un grupo alquilo provisto de 4 átomos de carbono a lo sumo Y es un cadena de hidrocarburo recta o ramificada con 6 átomos de carbono a lo sumosi se desea interrumpida por un átomo de oxígenoy Z representa un grupo dialquilamino en el cual uno de los grupos alquiloo ambosjunto con el átomo de nitrógeno ysi es necesariola cadena de carbono Ypueden formar uno o más anillos heterocíclicosen los cuales puede estar presenteademás de este átomo de nitrógenoun egundo heteroátomoy sales o compuestos amónicos cuaternarios de los mismos.
ES0256994A 1959-04-01 1960-03-31 Procedimiento para la preparaciën de derivados de dibenzocicloheptano terapeuticamente activos Expired ES256994A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL237664 1959-04-01

Publications (1)

Publication Number Publication Date
ES256994A1 true ES256994A1 (es) 1960-10-01

Family

ID=19751644

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0256994A Expired ES256994A1 (es) 1959-04-01 1960-03-31 Procedimiento para la preparaciën de derivados de dibenzocicloheptano terapeuticamente activos

Country Status (7)

Country Link
US (1) US3227716A (es)
CH (1) CH417574A (es)
ES (1) ES256994A1 (es)
GB (1) GB943603A (es)
NL (1) NL237664A (es)
OA (1) OA00466A (es)
SE (2) SE300617B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3369044A (en) * 1962-07-23 1968-02-13 Geigy Chem Corp 5-carboxylic acid halide derivatives of 10, 11-dihydro-5h-dibenzo[a, d]cycloheptene
BE664608A (es) * 1964-05-29
GB1091910A (en) * 1964-08-18 1967-11-22 Koninklijke Pharma Fab Nv New dibenzocycloheptenylamines
US3627832A (en) * 1964-10-16 1971-12-14 Sterling Drug Inc AMINO-LOWER-ALKOXY-DIBENZO{8 a,d{9 CYCLOHEPTENES AND 5-ALKYL and -ARALKYL DERIVATIVES
US3350405A (en) * 1964-10-16 1967-10-31 Sterling Drug Inc Amino-lower-alkoxy-dibenzo [a, d] cyclohepten-5-ones and 10, 11-dihydro derivatives thereof
FR176F (es) * 1965-05-19
US3317547A (en) * 1965-06-24 1967-05-02 Colgate Palmolive Co Quinuclidyl ethers of dibenzocycloheptadiene
US3466291A (en) * 1966-02-16 1969-09-09 Sandoz Ag 4(2-dialkylaminoethoxy or 2-piperidinoethoxy) - 9,10 - dihydro benzo(4,5)cyclohepta(1,2-b)thiophene derivatives
US4792551A (en) * 1983-07-15 1988-12-20 Syntex (U.S.A.) Inc. 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents
GB8816365D0 (en) * 1988-07-08 1988-08-10 Pfizer Ltd Therapeutic agents
US5231104A (en) * 1988-07-08 1993-07-27 Pfizer Inc. 1-arylethyl-3-substituted piperidines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2948732A (en) * 1960-08-09 N-heterocyclic compounds
US3014911A (en) * 1958-09-29 1961-12-26 Merck & Co Inc Derivatives of dibenzo[a, e]cycloheptatriene

Also Published As

Publication number Publication date
SE307940B (es) 1969-01-27
CH417574A (de) 1966-07-31
NL237664A (es)
OA00466A (fr) 1966-07-15
GB943603A (en) 1963-12-04
US3227716A (en) 1966-01-04
SE300617B (es) 1968-05-06

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