AU511027B2 - 1-(benzazolylalkyl) piperidine derivatives - Google Patents

1-(benzazolylalkyl) piperidine derivatives

Info

Publication number
AU511027B2
AU511027B2 AU15964/76A AU1596476A AU511027B2 AU 511027 B2 AU511027 B2 AU 511027B2 AU 15964/76 A AU15964/76 A AU 15964/76A AU 1596476 A AU1596476 A AU 1596476A AU 511027 B2 AU511027 B2 AU 511027B2
Authority
AU
Australia
Prior art keywords
benzazolylalkyl
piperidine derivatives
piperidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU15964/76A
Other versions
AU1596476A (en
Inventor
Ludo E.J. Kennis
Marcel J.M.C. Van Der Aa
Albert H.M.Th. Van Heertum
Jan Vandenberk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/687,139 external-priority patent/US4066772A/en
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of AU1596476A publication Critical patent/AU1596476A/en
Application granted granted Critical
Publication of AU511027B2 publication Critical patent/AU511027B2/en
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
AU15964/76A 1975-07-21 1976-07-16 1-(benzazolylalkyl) piperidine derivatives Expired AU511027B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US59779375A 1975-07-21 1975-07-21
US597793 1975-07-21
US687139 1976-05-17
US05/687,139 US4066772A (en) 1975-07-21 1976-05-17 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
KR7601697A KR810000334B1 (en) 1975-07-21 1976-07-12 Process for preparation 1-(benzazolylalkyl)-piperidine derivatives

Publications (2)

Publication Number Publication Date
AU1596476A AU1596476A (en) 1978-01-19
AU511027B2 true AU511027B2 (en) 1980-07-24

Family

ID=27348142

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15964/76A Expired AU511027B2 (en) 1975-07-21 1976-07-16 1-(benzazolylalkyl) piperidine derivatives

Country Status (25)

Country Link
JP (1) JPS5217475A (en)
AT (1) AT364358B (en)
AU (1) AU511027B2 (en)
BG (1) BG26526A3 (en)
CA (1) CA1085852A (en)
CH (1) CH623820A5 (en)
CS (1) CS202550B2 (en)
DE (1) DE2632870A1 (en)
DK (1) DK154950C (en)
ES (3) ES449740A1 (en)
FI (1) FI62667C (en)
GB (1) GB1542514A (en)
HK (1) HK14180A (en)
IE (1) IE43496B1 (en)
IT (1) IT1062614B (en)
KE (1) KE3215A (en)
LU (1) LU75354A1 (en)
MY (1) MY8100017A (en)
NL (1) NL187442C (en)
NZ (1) NZ181256A (en)
PH (1) PH13710A (en)
PT (1) PT65387B (en)
RO (1) RO70566A (en)
SE (2) SE426490B (en)
YU (1) YU39969B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
JPS6248684A (en) * 1985-08-26 1987-03-03 Sumitomo Chem Co Ltd Novel iodobutyrophenone derivative and production thereof
JPS62251313A (en) * 1986-04-25 1987-11-02 信越ポリマー株式会社 Bundling device
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES
US6355659B1 (en) 1994-07-29 2002-03-12 Laboratorios Del Dr. Esteve, S.A. 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same
JO2785B1 (en) 2003-05-27 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinazoline derivatives
EA013904B1 (en) 2003-12-18 2010-08-30 Янссен Фармацевтика Н.В. Pyrido- and pyrimidopyrimidine derivatives as anti- proliferative agents
NI200700147A (en) 2004-12-08 2019-05-10 Janssen Pharmaceutica Nv QUINAZOLINE DERIVATIVES KINE INHIBITORS TARGETING MULTIP
EP2044084B1 (en) 2006-07-13 2016-02-17 Janssen Pharmaceutica NV Mtki quinazoline derivatives
EP1997805A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
JP5536647B2 (en) 2007-07-27 2014-07-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Pyrrolopyrimidine
TWI448289B (en) 2007-08-31 2014-08-11 Purdue Pharma Lp Substituted-quinoxaline-type piperidine compounds and the uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
WO2017136617A1 (en) * 2016-02-04 2017-08-10 Cinrx Pharma, Llc Deuterated domperidone compositions and methods for therapy of disorders
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4698672A (en) * 1972-09-22 1972-11-09 Ciba-Geigy Ag Azacycloaliphatic compounds, process for their manufacture and compositions containing them
AU8113875A (en) * 1974-06-21 1976-11-18 Janssen Pharmaceutica Nv Benzimidazolinone derivatives
AU8192675A (en) * 1974-06-10 1976-12-16 Dr. Karl Thomae Gmbh 5(6)-pyridazin-6-yl-benzimidazole derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (en) * 1962-06-13
BE633914A (en) * 1962-06-22
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
FR2218100A1 (en) * 1973-02-20 1974-09-13 Janssen Pharmaceutica Nv Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4698672A (en) * 1972-09-22 1972-11-09 Ciba-Geigy Ag Azacycloaliphatic compounds, process for their manufacture and compositions containing them
AU8192675A (en) * 1974-06-10 1976-12-16 Dr. Karl Thomae Gmbh 5(6)-pyridazin-6-yl-benzimidazole derivatives
AU8113875A (en) * 1974-06-21 1976-11-18 Janssen Pharmaceutica Nv Benzimidazolinone derivatives

Also Published As

Publication number Publication date
GB1542514A (en) 1979-03-21
DK327576A (en) 1977-01-22
PT65387B (en) 1978-06-09
IT1062614B (en) 1984-10-20
JPS5217475A (en) 1977-02-09
SE435621B (en) 1984-10-08
RO70566A (en) 1982-10-11
DK154950C (en) 1989-05-29
JPS6131109B2 (en) 1986-07-17
NL187442C (en) 1991-10-01
IE43496B1 (en) 1981-03-11
DE2632870C2 (en) 1989-02-16
DE2632870A1 (en) 1977-02-10
KE3215A (en) 1982-07-09
LU75354A1 (en) 1977-02-28
SE8008713L (en) 1980-12-11
NL187442B (en) 1991-05-01
MY8100017A (en) 1981-12-31
SE7608265L (en) 1977-01-22
YU179476A (en) 1983-01-21
FI62667C (en) 1983-02-10
PH13710A (en) 1980-09-09
FI62667B (en) 1982-10-29
PT65387A (en) 1976-08-01
ES449740A1 (en) 1978-02-16
DK154950B (en) 1989-01-09
FI762086A (en) 1977-01-22
HK14180A (en) 1980-03-28
ES461630A1 (en) 1978-06-16
YU39969B (en) 1985-06-30
CA1085852A (en) 1980-09-16
NL7608023A (en) 1977-01-25
BG26526A3 (en) 1979-04-12
CS202550B2 (en) 1981-01-30
CH623820A5 (en) 1981-06-30
NZ181256A (en) 1978-04-28
AT364358B (en) 1981-10-12
ATA534776A (en) 1981-03-15
ES461631A1 (en) 1978-12-01
SE426490B (en) 1983-01-24
AU1596476A (en) 1978-01-19
IE43496L (en) 1977-01-21

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