DK154950C - METHOD OF ANALOGUE FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PIPERIDE INGREDIENTS OR THE PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PIPERIDE INGREDIENTS OR THE PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS

Info

Publication number
DK154950C
DK154950C DK327576A DK327576A DK154950C DK 154950 C DK154950 C DK 154950C DK 327576 A DK327576 A DK 327576A DK 327576 A DK327576 A DK 327576A DK 154950 C DK154950 C DK 154950C
Authority
DK
Denmark
Prior art keywords
benzazolylalkyl
analogue
preparation
acid addition
addition salts
Prior art date
Application number
DK327576A
Other languages
Danish (da)
Other versions
DK154950B (en
DK327576A (en
Inventor
Jan Vandenberk
Ludo E J Kennis
Marcel J M C Van Der Aa
Albert H M Th Van Heertum
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/687,139 external-priority patent/US4066772A/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK327576A publication Critical patent/DK327576A/en
Publication of DK154950B publication Critical patent/DK154950B/en
Application granted granted Critical
Publication of DK154950C publication Critical patent/DK154950C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
DK327576A 1975-07-21 1976-07-20 METHOD OF ANALOGUE FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PIPERIDE INGREDIENTS OR THE PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS DK154950C (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US59779375A 1975-07-21 1975-07-21
US59779375 1975-07-21
US68713976 1976-05-17
US05/687,139 US4066772A (en) 1975-07-21 1976-05-17 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
KR7601697A KR810000334B1 (en) 1975-07-21 1976-07-12 Process for preparation 1-(benzazolylalkyl)-piperidine derivatives
KR760001697 1976-07-12

Publications (3)

Publication Number Publication Date
DK327576A DK327576A (en) 1977-01-22
DK154950B DK154950B (en) 1989-01-09
DK154950C true DK154950C (en) 1989-05-29

Family

ID=27348142

Family Applications (1)

Application Number Title Priority Date Filing Date
DK327576A DK154950C (en) 1975-07-21 1976-07-20 METHOD OF ANALOGUE FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PIPERIDE INGREDIENTS OR THE PHARMACEUTICAL ACCEPTABLE ACID ADDITION SALTS

Country Status (25)

Country Link
JP (1) JPS5217475A (en)
AT (1) AT364358B (en)
AU (1) AU511027B2 (en)
BG (1) BG26526A3 (en)
CA (1) CA1085852A (en)
CH (1) CH623820A5 (en)
CS (1) CS202550B2 (en)
DE (1) DE2632870A1 (en)
DK (1) DK154950C (en)
ES (3) ES449740A1 (en)
FI (1) FI62667C (en)
GB (1) GB1542514A (en)
HK (1) HK14180A (en)
IE (1) IE43496B1 (en)
IT (1) IT1062614B (en)
KE (1) KE3215A (en)
LU (1) LU75354A1 (en)
MY (1) MY8100017A (en)
NL (1) NL187442C (en)
NZ (1) NZ181256A (en)
PH (1) PH13710A (en)
PT (1) PT65387B (en)
RO (1) RO70566A (en)
SE (2) SE426490B (en)
YU (1) YU39969B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
JPS6248684A (en) * 1985-08-26 1987-03-03 Sumitomo Chem Co Ltd Novel iodobutyrophenone derivative and production thereof
JPS62251313A (en) * 1986-04-25 1987-11-02 信越ポリマー株式会社 Bundling device
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES
US6355659B1 (en) 1994-07-29 2002-03-12 Laboratorios Del Dr. Esteve, S.A. 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same
PA8603801A1 (en) * 2003-05-27 2004-12-16 Janssen Pharmaceutica Nv DERIVATIVES OF QUINAZOLINE
DE602004012891T2 (en) 2003-12-18 2009-04-09 Janssen Pharmaceutica N.V. PYRIDO AND PYRIMIDOPYRIMIDIN DERIVATIVES AS ANTI-PROLIFERATIVE AGENTS
NI200700147A (en) 2004-12-08 2019-05-10 Janssen Pharmaceutica Nv QUINAZOLINE DERIVATIVES KINE INHIBITORS TARGETING MULTIP
AU2007274284B2 (en) 2006-07-13 2012-04-26 Janssen Pharmaceutica N.V. Mtki quinazoline derivatives
EP1997805A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
AU2008281849B2 (en) 2007-07-27 2013-11-28 Janssen Pharmaceutica Nv Pyrrolopyrimidines
MY150602A (en) 2007-08-31 2014-01-30 Purdue Pharma Lp Subtituted-quinoxaline-type piperidine compounds and the uses thereof
WO2014102594A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
KR20180104662A (en) * 2016-02-04 2018-09-21 신알엑스 파마, 엘엘씨 Deuterated domperidone compositions and methods for the treatment of disorders
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (en) * 1962-06-13
BE633914A (en) * 1962-06-22
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
AU4698672A (en) * 1972-09-22 1972-11-09 Ciba-Geigy Ag Azacycloaliphatic compounds, process for their manufacture and compositions containing them
FR2218100A1 (en) * 1973-02-20 1974-09-13 Janssen Pharmaceutica Nv Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones
US3989707A (en) * 1974-06-21 1976-11-02 Janssen Pharmaceutica N.V. Benzimidazolinone derivatives

Also Published As

Publication number Publication date
ES461630A1 (en) 1978-06-16
DK154950B (en) 1989-01-09
AT364358B (en) 1981-10-12
JPS5217475A (en) 1977-02-09
KE3215A (en) 1982-07-09
BG26526A3 (en) 1979-04-12
MY8100017A (en) 1981-12-31
RO70566A (en) 1982-10-11
SE7608265L (en) 1977-01-22
SE8008713L (en) 1980-12-11
NL187442B (en) 1991-05-01
AU1596476A (en) 1978-01-19
IE43496L (en) 1977-01-21
CA1085852A (en) 1980-09-16
IT1062614B (en) 1984-10-20
ES461631A1 (en) 1978-12-01
AU511027B2 (en) 1980-07-24
LU75354A1 (en) 1977-02-28
SE435621B (en) 1984-10-08
YU179476A (en) 1983-01-21
YU39969B (en) 1985-06-30
NL187442C (en) 1991-10-01
FI762086A (en) 1977-01-22
IE43496B1 (en) 1981-03-11
PT65387A (en) 1976-08-01
FI62667B (en) 1982-10-29
DE2632870C2 (en) 1989-02-16
CH623820A5 (en) 1981-06-30
FI62667C (en) 1983-02-10
ES449740A1 (en) 1978-02-16
PH13710A (en) 1980-09-09
HK14180A (en) 1980-03-28
CS202550B2 (en) 1981-01-30
NZ181256A (en) 1978-04-28
ATA534776A (en) 1981-03-15
JPS6131109B2 (en) 1986-07-17
DE2632870A1 (en) 1977-02-10
GB1542514A (en) 1979-03-21
SE426490B (en) 1983-01-24
DK327576A (en) 1977-01-22
PT65387B (en) 1978-06-09
NL7608023A (en) 1977-01-25

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