RO70566A - PROCESS FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PYPERIDINES - Google Patents

PROCESS FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PYPERIDINES

Info

Publication number
RO70566A
RO70566A RO7686860A RO8686076A RO70566A RO 70566 A RO70566 A RO 70566A RO 7686860 A RO7686860 A RO 7686860A RO 8686076 A RO8686076 A RO 8686076A RO 70566 A RO70566 A RO 70566A
Authority
RO
Romania
Prior art keywords
pyperidines
benzazolylalkyl
preparation
Prior art date
Application number
RO7686860A
Other languages
French (fr)
Romanian (ro)
Inventor
Jan Vandenverk
Ludo Kennis
Der Aa Marcel Van
Heertum Albert Van
Original Assignee
Janssen Pharmaceutica Nv,Be
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/687,139 external-priority patent/US4066772A/en
Application filed by Janssen Pharmaceutica Nv,Be filed Critical Janssen Pharmaceutica Nv,Be
Publication of RO70566A publication Critical patent/RO70566A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
RO7686860A 1975-07-21 1976-07-07 PROCESS FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PYPERIDINES RO70566A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59779375A 1975-07-21 1975-07-21
US05/687,139 US4066772A (en) 1975-07-21 1976-05-17 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
KR7601697A KR810000334B1 (en) 1975-07-21 1976-07-12 Process for preparation 1-(benzazolylalkyl)-piperidine derivatives

Publications (1)

Publication Number Publication Date
RO70566A true RO70566A (en) 1982-10-11

Family

ID=27348142

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7686860A RO70566A (en) 1975-07-21 1976-07-07 PROCESS FOR THE PREPARATION OF 1- (BENZAZOLYLALKYL) -PYPERIDINES

Country Status (25)

Country Link
JP (1) JPS5217475A (en)
AT (1) AT364358B (en)
AU (1) AU511027B2 (en)
BG (1) BG26526A3 (en)
CA (1) CA1085852A (en)
CH (1) CH623820A5 (en)
CS (1) CS202550B2 (en)
DE (1) DE2632870A1 (en)
DK (1) DK154950C (en)
ES (3) ES449740A1 (en)
FI (1) FI62667C (en)
GB (1) GB1542514A (en)
HK (1) HK14180A (en)
IE (1) IE43496B1 (en)
IT (1) IT1062614B (en)
KE (1) KE3215A (en)
LU (1) LU75354A1 (en)
MY (1) MY8100017A (en)
NL (1) NL187442C (en)
NZ (1) NZ181256A (en)
PH (1) PH13710A (en)
PT (1) PT65387B (en)
RO (1) RO70566A (en)
SE (2) SE426490B (en)
YU (1) YU39969B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
JPS6248684A (en) * 1985-08-26 1987-03-03 Sumitomo Chem Co Ltd Novel iodobutyrophenone derivative and production thereof
JPS62251313A (en) * 1986-04-25 1987-11-02 信越ポリマー株式会社 Bundling device
US6355659B1 (en) 1994-07-29 2002-03-12 Laboratorios Del Dr. Esteve, S.A. 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES
PA8603801A1 (en) * 2003-05-27 2004-12-16 Janssen Pharmaceutica Nv DERIVATIVES OF QUINAZOLINE
EA013904B1 (en) 2003-12-18 2010-08-30 Янссен Фармацевтика Н.В. Pyrido- and pyrimidopyrimidine derivatives as anti- proliferative agents
NI200700147A (en) 2004-12-08 2019-05-10 Janssen Pharmaceutica Nv QUINAZOLINE DERIVATIVES KINE INHIBITORS TARGETING MULTIP
BRPI0714211B8 (en) 2006-07-13 2021-05-25 Janssen Pharmaceutica Nv mtki quinazoline derivatives, their use and pharmaceutical composition comprising them
EP1997805A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
WO2009016132A1 (en) 2007-07-27 2009-02-05 Janssen Pharmaceutica Nv Pyrrolopyrimidines
EP2433937B1 (en) 2007-08-31 2016-06-29 Purdue Pharma LP Substituted-quinoxaline-type-piperidine compounds and the uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
CA3013123A1 (en) * 2016-02-04 2017-08-10 Cinrx Pharma, Llc Deuterated domperidone compositions and methods for therapy of disorders
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (en) * 1962-06-13
BE633914A (en) * 1962-06-22
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
AU4698672A (en) * 1972-09-22 1972-11-09 Ciba-Geigy Ag Azacycloaliphatic compounds, process for their manufacture and compositions containing them
FR2218100A1 (en) * 1973-02-20 1974-09-13 Janssen Pharmaceutica Nv Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones
US3989707A (en) * 1974-06-21 1976-11-02 Janssen Pharmaceutica N.V. Benzimidazolinone derivatives

Also Published As

Publication number Publication date
ES461630A1 (en) 1978-06-16
IE43496L (en) 1977-01-21
DE2632870C2 (en) 1989-02-16
LU75354A1 (en) 1977-02-28
SE426490B (en) 1983-01-24
DE2632870A1 (en) 1977-02-10
DK154950B (en) 1989-01-09
KE3215A (en) 1982-07-09
IE43496B1 (en) 1981-03-11
SE435621B (en) 1984-10-08
NL187442C (en) 1991-10-01
BG26526A3 (en) 1979-04-12
JPS6131109B2 (en) 1986-07-17
FI762086A (en) 1977-01-22
PT65387B (en) 1978-06-09
ATA534776A (en) 1981-03-15
YU39969B (en) 1985-06-30
ES461631A1 (en) 1978-12-01
DK327576A (en) 1977-01-22
SE7608265L (en) 1977-01-22
DK154950C (en) 1989-05-29
PT65387A (en) 1976-08-01
GB1542514A (en) 1979-03-21
FI62667C (en) 1983-02-10
MY8100017A (en) 1981-12-31
YU179476A (en) 1983-01-21
CA1085852A (en) 1980-09-16
NZ181256A (en) 1978-04-28
AU1596476A (en) 1978-01-19
NL187442B (en) 1991-05-01
JPS5217475A (en) 1977-02-09
CH623820A5 (en) 1981-06-30
AT364358B (en) 1981-10-12
NL7608023A (en) 1977-01-25
HK14180A (en) 1980-03-28
SE8008713L (en) 1980-12-11
CS202550B2 (en) 1981-01-30
ES449740A1 (en) 1978-02-16
PH13710A (en) 1980-09-09
FI62667B (en) 1982-10-29
AU511027B2 (en) 1980-07-24
IT1062614B (en) 1984-10-20

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