FI762086A - - Google Patents

Info

Publication number
FI762086A
FI762086A FI762086A FI762086A FI762086A FI 762086 A FI762086 A FI 762086A FI 762086 A FI762086 A FI 762086A FI 762086 A FI762086 A FI 762086A FI 762086 A FI762086 A FI 762086A
Authority
FI
Finland
Application number
FI762086A
Other languages
Finnish (fi)
Other versions
FI62667C (en
FI62667B (en
Inventor
Jan Vanderberk
Ludo E J Kennis
Marcel J M C Van Der Aa
Albert H M Th Van Heertum
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/687,139 external-priority patent/US4066772A/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI762086A publication Critical patent/FI762086A/fi
Priority to FI813935A priority Critical patent/FI65249C/en
Application granted granted Critical
Publication of FI62667B publication Critical patent/FI62667B/en
Publication of FI62667C publication Critical patent/FI62667C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
FI762086A 1975-07-21 1976-07-20 FOERFARANDE FOER FRAMSTAELLNING AV ANTIEMETISKA 1- (BENZAZOLYLALKYL) PIPERIDINDERIVAT FI62667C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI813935A FI65249C (en) 1975-07-21 1981-12-08 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ANALYTICAL PRODUCTS 1-ENYL-8-BENZIMIDAZOLE-1-YLPROPYL-1,3,8-TRIAZASPIRO (4,5) DEKA N - ONDERIVAT

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US59779375A 1975-07-21 1975-07-21
US59779375 1975-07-21
US05/687,139 US4066772A (en) 1975-07-21 1976-05-17 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
US68713976 1976-05-17
KR7601697A KR810000334B1 (en) 1975-07-21 1976-07-12 Process for preparation 1-(benzazolylalkyl)-piperidine derivatives
KR760001697 1976-07-12

Publications (3)

Publication Number Publication Date
FI762086A true FI762086A (en) 1977-01-22
FI62667B FI62667B (en) 1982-10-29
FI62667C FI62667C (en) 1983-02-10

Family

ID=27348142

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762086A FI62667C (en) 1975-07-21 1976-07-20 FOERFARANDE FOER FRAMSTAELLNING AV ANTIEMETISKA 1- (BENZAZOLYLALKYL) PIPERIDINDERIVAT

Country Status (25)

Country Link
JP (1) JPS5217475A (en)
AT (1) AT364358B (en)
AU (1) AU511027B2 (en)
BG (1) BG26526A3 (en)
CA (1) CA1085852A (en)
CH (1) CH623820A5 (en)
CS (1) CS202550B2 (en)
DE (1) DE2632870A1 (en)
DK (1) DK154950C (en)
ES (3) ES449740A1 (en)
FI (1) FI62667C (en)
GB (1) GB1542514A (en)
HK (1) HK14180A (en)
IE (1) IE43496B1 (en)
IT (1) IT1062614B (en)
KE (1) KE3215A (en)
LU (1) LU75354A1 (en)
MY (1) MY8100017A (en)
NL (1) NL187442C (en)
NZ (1) NZ181256A (en)
PH (1) PH13710A (en)
PT (1) PT65387B (en)
RO (1) RO70566A (en)
SE (2) SE426490B (en)
YU (1) YU39969B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
JPS6248684A (en) * 1985-08-26 1987-03-03 Sumitomo Chem Co Ltd Novel iodobutyrophenone derivative and production thereof
JPS62251313A (en) * 1986-04-25 1987-11-02 信越ポリマー株式会社 Bundling device
US6355659B1 (en) 1994-07-29 2002-03-12 Laboratorios Del Dr. Esteve, S.A. 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES
JO2785B1 (en) * 2003-05-27 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinazoline derivatives
JP4936897B2 (en) 2003-12-18 2012-05-23 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Pyrido- and pyrimidopyrimidine derivatives as antiproliferative agents
NI200700147A (en) 2004-12-08 2019-05-10 Janssen Pharmaceutica Nv QUINAZOLINE DERIVATIVES KINE INHIBITORS TARGETING MULTIP
JP2009542778A (en) 2006-07-13 2009-12-03 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ MTKI quinazoline derivative
EP1997805A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans
WO2009016132A1 (en) 2007-07-27 2009-02-05 Janssen Pharmaceutica Nv Pyrrolopyrimidines
KR20140139125A (en) 2007-08-31 2014-12-04 퍼듀 퍼머 엘피 Substituted-quinoxaline-type piperidine compounds and the uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
CA3013123A1 (en) * 2016-02-04 2017-08-10 Cinrx Pharma, Llc Deuterated domperidone compositions and methods for therapy of disorders
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (en) * 1962-06-13
BE633914A (en) * 1962-06-22
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
AU4698672A (en) * 1972-09-22 1972-11-09 Ciba-Geigy Ag Azacycloaliphatic compounds, process for their manufacture and compositions containing them
FR2218100A1 (en) * 1973-02-20 1974-09-13 Janssen Pharmaceutica Nv Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones
US3989707A (en) * 1974-06-21 1976-11-02 Janssen Pharmaceutica N.V. Benzimidazolinone derivatives

Also Published As

Publication number Publication date
CS202550B2 (en) 1981-01-30
AU511027B2 (en) 1980-07-24
IE43496L (en) 1977-01-21
HK14180A (en) 1980-03-28
DE2632870A1 (en) 1977-02-10
NL187442C (en) 1991-10-01
CA1085852A (en) 1980-09-16
IT1062614B (en) 1984-10-20
PT65387A (en) 1976-08-01
FI62667C (en) 1983-02-10
ES449740A1 (en) 1978-02-16
PH13710A (en) 1980-09-09
NL7608023A (en) 1977-01-25
DK154950B (en) 1989-01-09
ES461630A1 (en) 1978-06-16
LU75354A1 (en) 1977-02-28
MY8100017A (en) 1981-12-31
GB1542514A (en) 1979-03-21
FI62667B (en) 1982-10-29
ES461631A1 (en) 1978-12-01
DK154950C (en) 1989-05-29
AT364358B (en) 1981-10-12
YU179476A (en) 1983-01-21
SE8008713L (en) 1980-12-11
SE435621B (en) 1984-10-08
SE426490B (en) 1983-01-24
AU1596476A (en) 1978-01-19
IE43496B1 (en) 1981-03-11
DK327576A (en) 1977-01-22
NZ181256A (en) 1978-04-28
KE3215A (en) 1982-07-09
NL187442B (en) 1991-05-01
SE7608265L (en) 1977-01-22
DE2632870C2 (en) 1989-02-16
YU39969B (en) 1985-06-30
CH623820A5 (en) 1981-06-30
BG26526A3 (en) 1979-04-12
JPS6131109B2 (en) 1986-07-17
JPS5217475A (en) 1977-02-09
ATA534776A (en) 1981-03-15
RO70566A (en) 1982-10-11
PT65387B (en) 1978-06-09

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Legal Events

Date Code Title Description
MA Patent expired
MA Patent expired

Owner name: JANSSEN PHARMACEUTICA N.V.