CR10860A - Compuestos y metodos para modulacion de cinasas, e indicaciones para ello - Google Patents
Compuestos y metodos para modulacion de cinasas, e indicaciones para elloInfo
- Publication number
- CR10860A CR10860A CR10860A CR10860A CR10860A CR 10860 A CR10860 A CR 10860A CR 10860 A CR10860 A CR 10860A CR 10860 A CR10860 A CR 10860A CR 10860 A CR10860 A CR 10860A
- Authority
- CR
- Costa Rica
- Prior art keywords
- compounds
- methods
- kinases
- indications
- modulation
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Emergency Medicine (AREA)
Abstract
Se describen compuestos activos sobre proteina cinasas, asi como metodos para usar tales compuestos para tratar enfermedades y padecimientos asociados con actividad aberrante de proteina cinasas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87695306P | 2006-12-21 | 2006-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR10860A true CR10860A (es) | 2009-06-30 |
Family
ID=39281754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10860A CR10860A (es) | 2006-12-21 | 2009-06-11 | Compuestos y metodos para modulacion de cinasas, e indicaciones para ello |
Country Status (24)
Country | Link |
---|---|
US (2) | US7863289B2 (es) |
EP (1) | EP2097414A1 (es) |
JP (1) | JP2010514687A (es) |
KR (1) | KR20090095654A (es) |
CN (1) | CN101668757A (es) |
AR (1) | AR064476A1 (es) |
AU (1) | AU2007336906A1 (es) |
BR (1) | BRPI0722088A2 (es) |
CA (1) | CA2673000A1 (es) |
CL (1) | CL2007003797A1 (es) |
CO (1) | CO6190519A2 (es) |
CR (1) | CR10860A (es) |
EC (1) | ECSP099444A (es) |
HN (1) | HN2009001202A (es) |
MA (1) | MA31153B1 (es) |
MX (1) | MX2009006162A (es) |
MY (1) | MY148468A (es) |
NO (1) | NO20092251L (es) |
PE (2) | PE20081581A1 (es) |
RU (1) | RU2009122436A (es) |
TW (1) | TW200845975A (es) |
UA (1) | UA98629C2 (es) |
UY (1) | UY30816A1 (es) |
WO (2) | WO2008079906A1 (es) |
Families Citing this family (173)
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US20090118139A1 (en) * | 2000-11-07 | 2009-05-07 | Caliper Life Sciences, Inc. | Microfluidic method and system for enzyme inhibition activity screening |
US7504509B2 (en) | 2003-12-19 | 2009-03-17 | Plexxikon, Inc. | Compounds and methods for development of Ret modulators |
US7498342B2 (en) * | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
AU2006272951A1 (en) * | 2005-05-17 | 2007-02-01 | Plexxikon, Inc. | Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors |
AU2006261993B2 (en) * | 2005-06-22 | 2011-11-17 | Plexxikon, Inc. | Pyrrolo (2, 3-B) pyridine derivatives as protein kinase inhibitors |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
WO2008079909A1 (en) * | 2006-12-21 | 2008-07-03 | Plexxikon, Inc. | Pyrrolo [2,3-b] pyridines as kinase modulators |
PE20081581A1 (es) * | 2006-12-21 | 2008-11-12 | Plexxikon Inc | COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA |
US7872018B2 (en) | 2006-12-21 | 2011-01-18 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
EP2170830B1 (en) | 2007-07-17 | 2014-10-15 | Plexxikon, Inc. | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS |
WO2009099982A1 (en) * | 2008-02-04 | 2009-08-13 | Osi Pharmaceuticals, Inc. | 2-aminopyridine kinase inhibitors |
AR070317A1 (es) * | 2008-02-06 | 2010-03-31 | Osi Pharm Inc | Furo (3,2-c) piridina y tieno (3,2-c) piridinas |
CN101952294B (zh) | 2008-02-25 | 2014-11-26 | 霍夫曼-拉罗奇有限公司 | 吡咯并吡嗪激酶抑制剂 |
WO2009106442A1 (en) * | 2008-02-25 | 2009-09-03 | F. Hoffmann-La Roche Ag | Pyrrolopyrazine kinase inhibitors |
CA2713324A1 (en) | 2008-02-25 | 2009-09-03 | F. Hoffmann-La Roche Ag | Pyrrolopyrazine kinase inhibitors |
MX2010009023A (es) | 2008-02-25 | 2010-09-07 | Hoffmann La Roche | Inhibidores de cinasas de pirrolopirazina. |
WO2009106445A1 (en) * | 2008-02-25 | 2009-09-03 | F. Hoffmann-La Roche Ag | Pyrrolopyrazine kinase inhibitors |
PE20091561A1 (es) * | 2008-02-29 | 2009-10-30 | Array Biopharma Inc | Compuestos inhibidores de raf y metodos para su uso |
US20110003809A1 (en) * | 2008-02-29 | 2011-01-06 | Array Biopharma Inc. | Imidazo [4,5-b] pyridine derivatives used as raf inhibitors |
AU2009222144A1 (en) | 2008-02-29 | 2009-09-11 | Array Biopharma Inc. | Pyrazole [3, 4-b] pyridine Raf inhibitors |
CA2716949A1 (en) * | 2008-02-29 | 2009-09-11 | Array Biopharma Inc. | N- (6-aminopyridin-3-yl) -3- (sulfonamido) benzamide derivatives as b-raf inhibitors for the treatment of cancer |
WO2009143018A2 (en) | 2008-05-19 | 2009-11-26 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
US20110274661A1 (en) * | 2008-08-11 | 2011-11-10 | The University Of Chicago | Attentuated Herpesvirus Encoding a Mek Pathway Polypeptide |
US8450322B2 (en) | 2008-09-22 | 2013-05-28 | Array Biopharma Inc. | Substituted imidazo[1,2b]pyridazine compounds as Trk kinase inhibitors |
MX2011004953A (es) | 2008-11-10 | 2011-12-14 | Vertex Pharma | Compuestos utiles como inhibidores de cinasa atr. |
JP2012509342A (ja) * | 2008-11-20 | 2012-04-19 | オーエスアイ・フアーマスーテイカルズ・インコーポレーテツド | 置換ピロロ[2,3−b]−ピリジンおよび−ピラジン |
CN102300862B (zh) | 2008-12-19 | 2016-11-23 | 沃泰克斯药物股份有限公司 | 用作atr激酶抑制剂的化合物 |
KR20110130463A (ko) * | 2009-03-11 | 2011-12-05 | 플렉시콘, 인코퍼레이티드 | Raf 키나제의 억제를 위한 피롤로[2,3-b]피리딘 유도체 |
EP2406259A1 (en) * | 2009-03-11 | 2012-01-18 | Plexxikon, Inc. | Pyrrolo [2, 3-b]pyridine derivatives for the inhibition of raf kinases |
WO2010111527A1 (en) * | 2009-03-26 | 2010-09-30 | Plexxikon, Inc. | Pyrazolo [ 3, 4 -b] pyridines as kinase inhibitors and their medical use |
AU2010232670B2 (en) | 2009-04-03 | 2015-07-09 | F. Hoffmann-La Roche Ag | Propane- I-sulfonic acid {3- [5- (4 -chloro-phenyl) -1H-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof |
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- 2007-12-19 WO PCT/US2007/088237 patent/WO2008079906A1/en active Application Filing
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CL2007003797A1 (es) | 2008-07-18 |
HN2009001202A (es) | 2012-06-04 |
AU2007336906A1 (en) | 2008-07-03 |
JP2010514687A (ja) | 2010-05-06 |
WO2008079903A1 (en) | 2008-07-03 |
US20080167338A1 (en) | 2008-07-10 |
EP2097414A1 (en) | 2009-09-09 |
TW200845975A (en) | 2008-12-01 |
RU2009122436A (ru) | 2011-01-27 |
UA98629C2 (ru) | 2012-06-11 |
KR20090095654A (ko) | 2009-09-09 |
MX2009006162A (es) | 2009-06-19 |
CA2673000A1 (en) | 2008-07-03 |
AR064476A1 (es) | 2009-04-01 |
US20110092538A1 (en) | 2011-04-21 |
MY148468A (en) | 2013-04-30 |
PE20121126A1 (es) | 2012-08-24 |
CO6190519A2 (es) | 2010-08-19 |
ECSP099444A (es) | 2009-07-31 |
WO2008079906A1 (en) | 2008-07-03 |
UY30816A1 (es) | 2008-07-31 |
NO20092251L (no) | 2009-07-15 |
CN101668757A (zh) | 2010-03-10 |
BRPI0722088A2 (pt) | 2016-03-22 |
MA31153B1 (fr) | 2010-02-01 |
PE20081581A1 (es) | 2008-11-12 |
US7863289B2 (en) | 2011-01-04 |
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