CN1806475B - 具有集成天线的印刷电路装置和具有集成印刷电路板天线的可植入传感器处理系统 - Google Patents
具有集成天线的印刷电路装置和具有集成印刷电路板天线的可植入传感器处理系统 Download PDFInfo
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Abstract
一种与以电感方式进行功率和数据传输应用结合使用的印刷电路装置主要由铁氧体材料形成,并且有电感线圈导线环绕着基板形成,以增加用于实现功率和数据传输两种功能的线圈的电磁性能,从而,不再需要与电路装置连接的分立铁氧体磁芯线绕线圈。
Description
本申请要求2003年4月15日提交的美国临时专利申请No.60/462695的优先权。
技术领域
本发明总体上涉及用于无线数据传输和对无线数据传输装置的电感供电(inductive powering)的电子装置和方法。特别地讲,本发明涉及用于探测和测量介质例如人体中的某些特征参数的可植入装置和方法。
背景技术
作为结合在此作为参考的公开物的美国专利No.5517313描述了一种荧光传感装置,其包括一组分层的含有荧光指示剂分子的基体(以后称为“荧光基体”)、一个高通滤光器以及一个光电探测器。在所述装置中,一个光源(优选为发光二极管,简称“LED”)至少部分位于指示剂材料内,从而,来自所述光源的入射光线可使所述指示剂分子发出荧光。所述高通滤光器可使发出的光线到达所述光电探测器,并且同时可从所述光源中滤出散射的入射光线。分析物可渗透到所述荧光基体中,使指示剂材料的荧光性能与存在的分析物的量成比例地变化。然后,由所述光电探测器探测和测量荧光发射,从而,可测量出感兴趣的环境内所存在的分析物的量和浓度。
′313专利中所公开类型的传感器装置的一种有利应用是将所述装置植入人体皮下或静脉中,以在任何期望时刻可瞬时测量分析物。例如,可用于测量处于麻醉之中的患者血液中的氧和糖尿病患者的血液中的葡萄糖的浓度。
由于植入人体中的传感器装置会受到尺寸和可达性限制,因此存在很多与商业单元的生产相关的问题,其中,小型化的要求会引起可靠性、制造成本效益以及性能问题。例如,为所述传感装置设置数据传输电路和/或电源将会使所述装置植入人体中所要求的尺寸增大。
作为整体结合在此也作为参考的公开物的美国专利No.6400974讲述了一种用于处理植入人体中的传感器的输出信号的处理系统,其不需要数据传输电路或内部电源。′974专利讲述了一种处理电路,其通过由所述处理电路发射的电感耦合RF能量为所述传感器提供电能。所述处理电路从所述植入传感器接收数据传输,以形成处理电路上的负载的变化。RF能量耦合和数据传输通过提供如下两个线圈实现,即位于植入传感器装置内的小线圈和与外部处理电路连接的较大线圈。
小线圈的一种可能的实现方法是使用一种具有连接在印刷电路板(PCB)上的分立铁氧体磁芯(discrete ferrite core)的线绕线圈。尽管这种实现方法可以令人接受,但仍可以做出改进。
例如,分立线绕铁氧体磁芯与PCB的连接会非常困难,并且会产生可靠性的问题,而且会导致制造产量低。
其次,由于制造商所售的每个线绕线圈的特性因存在制造公差而会稍有不同,因此,需要单个地调整每个传感器装置,以与相关天线的工作频率正确匹配。
另外,所述线绕线圈的物理结构可在所述传感器装置的体积排量(volumetric displacement)内产生非常多的空隙空间,这样,就可在电子电路需要的聚合物罩套内形成气泡,从而,会使装置失效。
另一问题是需要所述线绕线圈铁氧体磁芯与PCB轴向对正。设置在要与PCB连接的所述线圈上的弯曲线系链引线的对正可使所述传感器包的径向尺寸比植入应用所必需或希望的尺寸大。
最后,分立线绕线圈的尺寸会限制传感器装置包的总体尺寸;进一步降低装置的尺寸以实现植入应用一直是人们所希望的。
鉴于以上所述,在本领域中迫切需要一种改进的可植入传感器装置。
发明内容
根据本发明的第一个方面,公开了一种印刷电路装置,其包含:基板,其主要由铁氧体材料制成,所述基板具有上下表面和沿着较大尺寸方向延伸的位于所述上下表面之间的第一和第二侧面以及沿着较小尺寸方向延伸的位于所述上下表面之间的第一和第二端面;至少一个元件(集成电路(IC)芯片、分立模拟元件或ASIC芯片),其安装在所述基板的主表面上;以及导线,其形成在所述基板上,并且以线圈的形式延伸过所述基板的至少一个表面。
根据本发明的第二个方面,公开了一种荧光传感器装置,其包含:光源,其用于将光线导入与介质相互作用的荧光指示剂中;光电探测器,其用于响应导入光线探测由所述荧光指示剂发射的光线和用于输出与探测光线成比例的信号,所述荧光指示剂的反应根据所述介质中的分析物的存在与否和数量而变化;线圈,其用于从外部电源接收电能和用于将所述信号传输给外部处理装置;以及基板,其主要由铁氧体材料形成,所述光源和所述光电探测器安装在所述基板的第一部分上,并且所述线圈以环绕着所述基板的相反表面延伸的方式形成在所述基板的第二部分上。
附图说明
下面,结合附图详细地描述优选实施例,可以更充分地理解本发明,所述附图仅用作说明目的,因此不会限制本发明,附图包括:
图1是根据本发明的一个优选实施例的传感器装置电路板的俯视图;
图2是图1中的所述传感器装置电路板的侧视图;
图3是图1中的所述传感器装置电路板的仰视图;
图4是根据本发明的另一个实施例的传感器装置电路板的局部侧视图;
图5是包含根据本发明的另一个实施例的传感器装置电路板的传感器装置的剖视图;
图6是根据本发明的可植入的基于荧光的传感器的示意性剖视图;
图7是图6中所示的所述基于荧光的传感器的示意图,示出了所述传感器的波导特性;
图8是图6中的圆形部分的详细视图,说明了所述传感器的本体的内部反射和传感器/组织分界面层的优选结构;以及
图9是作为本发明的另一个方面的用作低通滤波器的铁氧体磁珠的示意图。
具体实施方式
图1示出了根据本发明的传感器装置电路板的一个优选实施例的俯视图。图2和3分别示出了所述传感器装置电路板的侧视图和仰视图。
根据本发明的一个优选实施例,传感器装置电路板100包含一个主要由铁氧体材料制成的基板101。所述基板具有主上下表面101a和101b、沿着所述上下表面的较小尺寸方向延伸的端面101e和101f以及沿着所述上下表面的较大尺寸方向延伸的侧面101c和101d。所述基板优选由线圈部分110和集成电路(IC)部分112组成。IC部分112包含各种电路元件103和发光二极管(LED)芯片104(不同的LED用于不同的测量),它们由印刷线路105(为了说明目的,图1中示出的是任意图案)互连起来,其中,所述电路元件103可以是IC芯片、模拟元件等。
尽管本发明的所述电路装置被结合一个优选实施例描述为电路“板”,但其并不局限于任何特殊的形状或结构。根据其他实施例,铁氧体电路装置可包括至少一个供电子元件优选附装的大致平坦表面和包围着所述上下表面的曲线形状的侧面。例如,所述铁氧体电路装置可具有一个呈大致椭圆形或圆形的大致平坦表面。在另一个实例中,所述铁氧体电路装置可具有大致平坦上表面和例如与足球的一半或2/3类似的弯曲下表面。在又一个实施例中,铁氧体磁芯可为杆状。在另一个实施例中,所述铁氧体磁芯被成形得不具有大致平坦表面。
而且,尽管本发明的一个优选实施例已被描述为在所述基板的第一部分上具有一个线圈部分和作为所述基板的第二部分的IC部分,但本发明并不局限于这种结构。例如,根据其他实施例,电路元件可安装在线圈的上部,从而,可形成较厚但较短的传感器。此外,图6中所示的传感器可具有一个全长线圈。
根据本发明的一个优选实施例,所述铁氧体基板中除侧面以外的要被金属化或施加电路元件的表面预涂覆着市场上有售的可在高温下点燃的玻璃油灰,以形成一个惰性表面区域用于上述这种金属化处理和/或元件连接。所述基板中的要施放线圈的表面均可预涂覆着玻璃油灰,或一些表面可预涂覆而其他表面没有预涂覆,或上述表面均没有预涂覆。优选铁氧体材料的配方的一种实例是Countis C-48;然而,对于本领域的普通技术人员来说,也可开发出专门的铁氧体配方,以最优地用于特殊应用场合。如此所用,术语“主要由铁氧体材料”包括任何或所有这些配方。
出于小型化和能量传输方面的考虑,用于可植入传感器应用场合下的所述铁氧体基板的厚度可为近似10密耳至近似250密耳,优选为近似20密耳至100密耳,最优选为近似30密耳(0.030英寸)。如果所述铁氧体铁芯呈大致杆状或其他曲面形状,杆状或曲面的直径可为近似10密耳至250密耳,优选为20密耳至100密耳,最优选为近似30密耳。而且,对于本领域的普通技术人员来说,也可使用其他厚度,以使其他应用和考虑因素例如尺寸、频率和功率电平最优化。
线圈部分110包含一个细长线圈106,其优选被边缘缠绕(edge-wrapping)到所述铁氧体基板的周围。线圈106由任何合适的导电材料例如铜、金、银或合金制成。线圈106也可由与印刷线路105相同类型的材料制成。如图3所示,线圈106的末端可直接与形成在所述铁氧体基板上的金属化触点107连接。导电线圈材料优选使用边缘缠绕技术形成在铁氧体基板101上。然而,也可使用本领域中公知的其他形成技术。而且,尽管所述线圈如图1所示缠绕着所述主表面和所述侧面上,但通过使用仅延伸过一个主表面或仅环绕着所述侧面延伸的线圈也可获得相同的效果。
通过使整个所述印刷电路板由铁氧体材料制成,可提供单一均质基板,从而,可使用标准印刷电路制造技术执行传感器装置制造过程。(可选择性地,薄的电介质层可以涂层的方式涂在铁氧体上)。使用标准陶瓷基板的所有可使用的制造技术也可使用铁氧体基板,这些制造技术包括厚膜和薄膜印刷电阻和电容、引线接合、表面安装技术(SMT)、倒装芯片以及板上芯片技术(COB)。
而且,可省去在铁氧体磁芯线绕线圈中使用的线路连接操作。例如,缠绕线圈106可使用标准金属化连续表面布线技术连接在电路的其他部分上。可实现自动化操作的这种技术可使物理特性具有非常高的重复性、均质性,并能获得对植入应用而言异常重要的高的可靠性,而且可提高制造的成本效益。
此外,通过使整个印刷电路板由铁氧体材料形成,铁氧体的长度在分立铁氧体磁芯缠绕线圈上可得到显著增加。例如,铁氧体的长度可在分立铁氧体磁芯缠绕线圈上来回折叠五次而得到增加。这样,与分立铁氧体磁芯线绕线圈相比,就可显著增加外部处理单元(未示出,见′974专利)的电源的能量传输效率。
使用铁氧体基板所提供的另外一个优点是杂波抑制。使导线布线通过形成于所述铁氧体基板中的孔或导通孔将会以与图9所示相同的方式抑止高频能量,其中,铁氧体磁珠901在电路引线902周围用作低通滤波器。所述电路引线通过所述铁氧体磁珠可抑抑止通过引线902的电流的高频成分。相反地,在不希望产生这种抑制的情况下,线圈保持在所述铁氧体基板之外非常重要。
参看图6所示的基于荧光指示剂分子的荧光操作的传感器10的一个实施例,可说明使用铁氧体材料基板降低其他电路元件的杂波作用的有利之处。传感器10由一个传感器本体12;一个基体层14,其涂覆在传感器本体12的外表面上,并且其中散布着荧光指示剂分子16;一个辐射源18,例如LED,其发射射线,所述射线包括可与指示剂分子相互作用的波长或波长范围内的射线(在基于荧光的传感器的情况下)和可使指示剂分子16发出荧光的波长或波长范围内的射线;以及一个光敏元件20,例如光电探测器,在基于荧光的传感器的情况下,其对由指示剂分子16发出的荧光敏感,从而会产生表示指示剂分子的荧光的亮度的信号。传感器10还包含一个含有电子电路的模块或壳体66以及一个用于读取温度的温度传感器64。
为了使从探测器20的读数的精确度到达最大化,应使入射到探测器20的探测面上的背景光的影响最小化。实现上述目的一种方法是使用高频激励信号驱动LED,从而,探测器20上的背景光的影响可得到消除。然而,用于驱动LED的高频信号可增加不良的板上杂波,目前在设计其他部分电路的过程中必需予以考虑。
不良的板上电杂波(noise)也可能来自于其他源。具有由强的高频磁场激励的线圈106的传感器10可由高频磁场包围和穿过。上述高频信号可使电路的各个部分例如传感器10的LED 18中的不良的板上电杂波增加,从而会不利地影响整个装置的操作。
借助于根据本发明的用作PCB的铁氧体基板,高频杂波对其他电路元件的不利影响可例如通过使驱动引线借助“导通孔”布线穿过所述铁氧体基板而得到显著降低。如图4所示,根据本发明的上述方面,导通孔401穿过铁氧体基板101形成。LED 104安装在基板101的一侧,驱动电路405可安装在基板101的相反侧。来自驱动电路405的驱动信号导线403被通过导通孔401布线至LED 104,从而,可降低高频杂波对LED驱动的影响。当需要滤掉杂波时,所述铁氧体基板可被构造得具有多于一个的导通孔。来自多于一个的电路元件的引线可被布线穿过相同的导通孔或不同的导通孔。
根据本发明的另一个方面,照射到所述光电探测器上的背景光的不良影响得到了降低,并且通过将所述光电探测器移动至所述铁氧体基板中的与LED的安装面相反的下表面上,光电探测器的视场也可得到降低。上述情况示于图5中。
通过描述,如图7所示,射线(例如,光线)由辐射源18发射,并且至少一些上述射线会在传感器本体12的表面上例如位置22处向传感器本体12的内部反射,从而,可使射线来回“回弹”遍布传感器本体12的内部。
已经发现,从所述传感器本体与周围介质的分界面反射的光线可与涂覆在上述表面上(不管是直接涂覆在上面还是包含于基体中)的指示剂分子相互作用,例如可激发涂覆在上述表面上的荧光指示剂分子发出荧光。而且,照射到所述分界面上的角度(相对于所述分界面的法线方向测量的)太小而不能发生反射的光线会通过所述分界面,并且也会激发荧光指示剂分子发出荧光。还已经发现,光线(或其他射线)、所述分界面以及所述指示剂分子之间的相互作用也可根据所述传感器的结构和应用场合采用其他模式。上述其他模式包括渐消激发和表面等离子体谐振型激发。
如图8所示,至少有一些由荧光指示剂分子16发射的光线会如区域30中所示直接或经基体层14的最外表面(相对于传感器本体12)反射之后进入到传感器本体12中。与由辐射源18发射的射线非常类似,随后,这种荧光28会在内部传播遍布传感器本体12,并且与由所述辐射源发射的射线相似,一些荧光会以太小而不能发生反射的角度照射到所述传感器本体与周围介质之间的分界面上,从而会逃出所述传感器本体。
在如图6所示的现有传感器实施例中,在由光敏材料制成的光电探测器20的光敏面上优选设置有滤光片34。从现有技术可知,滤光片34可防止辐射源18产生的射线照射在光敏元件20的光敏面上或显著地降低由辐射源18产生的射线照射在光敏元件20的光敏面上的量。同时,所述滤光片可使由所述荧光指示剂分子发射的荧光穿过,以照射所述探测器的光敏区域。这样,就可十分显著地降低光电探测器信号中的由辐射源18的入射射线所引起的杂波。
使用铁氧体基板代替传统的白陶瓷基板所提供的另外一个显著优点是,黑色的铁氧体材料可比传统的白陶瓷电路板基板吸收更多的入射光线,从而,会散射较少的入射光线。
如图5所示,传感器装置501含有一个铁氧体PCB 101和封装在传感器本体503内的相关电路元件。一个光学ASIC控制器505和其他相关元件507例如IC与LED 104以及光电二极管511a、511b一同安装在所述铁氧体基板上。在操作过程中,光电二级光511a用于测量发射的荧光信号,光电二极管511b用于测量参考信号。在一个替代性实施例中,光电二极管511b用于测量与不同波长或所放置的不同指示剂对应的单独指示剂信号,以例如在相同的传感器中测量两种不同的分析物。第一和第二环氧滤光片509a和509b通过在基板中钻孔并用环氧滤光材料填充这些孔形成在所述铁氧体基板中。作为一种替代性方法,精密制作的玻璃滤光片也可粘在所述孔中。
通过将光电二极管511a和511b安装在所述铁氧体基板中的位于滤光片509a和509b正下方的下表面上,所述光电二极管没有荧光指示剂基体易受散射LED和背景光的影响;因此,与传统的白陶瓷电路板基板相比,所述铁氧体基板的上表面不会使入射到上表面上的光线发生任何显著量的反射。而且,通过将所述光电探测器从PCB基板的上表面移到下表面上,来自所述指示剂基体的较大角度的光线可照射到所述光电探测器表面上。因此,可有较多的信号光线用于产生光电探测器信号,从而,可进一步增加定量测量的准确性。由于所述滤光片可放置在所述基板内,因此上述这种结构可进一步提升小型化水平,从而不会占用比所述基板的厚度大的空间。
传感器本体503有利地由合适的光传输聚合材料(有机或无机)制成,其将充当光波导体。优选材料是丙烯酸类聚合物例如聚甲基丙烯酸甲酯、聚羟基丙烯酸甲酯(polyhydroxypropylmethacrylate)和类似物以及诸如市场上所售的商标为的聚碳酸酯。上述材料可使辐射源104产生的射线(例如,在所述辐射源为LED的实施例中合适波长的光线)和在基于荧光的实施例的情况下由所述指示剂分子发射的荧光传播通过。
还如图6中所示,传感器10还可包含反射涂层32,所述反射涂层32在传感器本体12的端部上形成于所述传感器本体与基体层14之间,以使所述射线和/或由荧光指示剂分子发射的光线的内部反射最大化或得到增强。所述反射涂层可例如由涂料或由金属化材料形成。
开发根据本发明的一个方面的传感器10的特殊应用是测量人体中各种生物分析物,例如葡萄糖、氧、毒素、药物或其他药剂、生物分子、荷尔蒙以及其他代谢分析物,但是其决不是唯一合适的应用。基体层14和指示剂分子16的具体组分可根据所述传感器用于探测的特殊分析物和/或所述传感器用于探测何处的所述分析物(例如,在血液中或在皮下组织中)变化。然而,两个优选特征是,基体层14便于使所述指示剂分子暴露给所述分析物和所述指示剂分子的光学特性(例如荧光指示剂分子的荧光级)是所述指示剂分子所暴露给的特定分析物的浓度的函数。
为了便于在人体中原位就地使用,传感器10被优选形成为光滑椭圆形或圆形形状。有利地,传感器10具有豆子或医用明胶胶囊的近似大小和形状,即其长度L为近似300-500微米至近似0.5英寸左右,深度D为近似300微米至近似0.3英寸左右,并且整个具有大致光滑的圆形表面。当然,上述装置可根据所用的材料和所述装置的预期使用场合较大或较小些。上述结构可使传感器10植入人体中即置于皮肤或皮下组织中(包括植入器官或血管中),并且不会使所述传感器干涉基本的身体功能或引起过大的痛苦或不适。
而且,应当指出,简单地依据植入物会引起刺激的事实,放置在人(或其他任何动物)体内的任何植入物即使是由“生物适应性”材料构成的植入物也会在某种程度上使植入物所插入的生物体内产生“异体反应”。在传感器10植入人体内的情况下,“异体反应”绝大部分通常为纤维化包裹,即疤痕组织的形成。作为根据本发明的传感器期望探测的主要分析物的葡萄糖的扩散或输送速率会受到这种纤维化包裹的阻碍。甚至非常小的氧分子(O2)的扩散和输送速率也会受到这种纤维化包裹的阻碍。这完全是因为形成纤维化包裹(疤痕组织)的细胞本性就非常密集或具有与正常组织不同的代谢特征。
为了克服上述这种对所述指示剂分子暴露给生物分析物的潜在阻碍或妨碍,想到了两个主要方法。根据一种或许最为简单的方法,传感器/组织分界面层由可使纤维化包裹很少形成或处于可接受的范围内的材料制备,所述传感器/组织分界面层在所述指示剂分子直接固定在所述传感器本体的表面上时遮盖着传感器本体12和/或所述指示剂分子它们本身的表面,或在所述指示剂分子包含在基体层14中时遮盖着基体层14的表面。文献中所描述的具有上述特征的这种材料的两个实例是可从W.L.Gore公司获得的PrecludTM Periocardial Membrane和与亲水物共价结合形成的聚异丁烯,后者描述于1994年2月出版的《化学工艺》中24-31页的Kennedy所撰写的“Tailoring Polymers for Biological Uses”一文中。
作为一种替代性方法,可在所述传感器上设置由多层专用的生物适应性材料构成的传感器/组织分界面层。如图8所示,例如,传感器/组织分界面层36可包含三个子层36a、36b和36c。作为促进组织长入的层的子层36a优选由当纤维化细胞39(疤痕组织)聚集在其上时可使毛细管37穿入的生物适应性材料制成。已使用多年的血管移植材料(ePTFE)和(PET)血管移植材料以及由高密度聚乙烯生产的多孔聚乙烯(MEDPOR)生物材料(可从POREX医疗设备公司获得)均为材料实例,它们的基本成分、孔径大小和细孔结构可促进组织和血管长入组织长入层中。
另一方面,子层36b优选为孔径(小于5微米)比组织长入子层36a的孔径显著小的生物适应性层,以防止组织长入。子层36b目前所优选的制造材料是可从W.L.Gore公司获得的PrecludePeriocardial Membrane(以前称为GORE-TEX手术膜),其由膨体聚四氟乙烯(ePTFE)组成。
第三子层36c用作分子筛,即其提供分子量筛选功能,其可排除诸如免疫球蛋白、蛋白质和糖蛋白之类的分子,同时又可使感兴趣的分析物通过到达所述指示剂分子(直接涂覆在传感器本体12上或固定于基体层14中)。许多众所周知的纤维素型膜,例如肾透析滤筒中所使用的这种纤维素型膜可用于分子量筛选层36c。
可以认为,图6中所示的传感器为完全独立式的,从而,不需要有电引线伸入或伸出所述传感器本体以向所述传感器提供电能(例如,用于驱动辐射源18)或从所述传感器传输信号。如图6所示,图2中所示的所有电子器件均可容纳在模块66中。
也可以认为,图6-8中所示的基于荧光的传感器实施例仅仅是公开的本发明可以应用的实例。本发明也可应用于其他许多应用场合,例如结合在此作为参考的1999年8月28日提交的美国专利申请No.09/383148中描述的基于吸光率的传感器或基于折射率的传感器。
对于本领域的普通技术人员来说,可在不脱离本发明的精神和范围的前提下以多种方式改变已如此描述的本发明。例如,尽管已参照了一种植入传感器装置描述本发明,但本发明的原理可应用于任何具有使用板上数据的无线通信功能或信号能量传输功能的印刷电路板。任何和所有这种修改均包含于权利要求书之中。
Claims (11)
1.一种具有形成在印刷电路装置上的集成电路和用于数据和/或能量传输的电感线圈的电子装置,其特征在于:
主要由铁氧体材料形成所述印刷电路装置的基板,使得所述基板包括线圈部分和单独的电路元件部分;
所述电感线圈形成为环绕印刷电路装置的所述基板的所述线圈部分,所述印刷电路装置的基板用作所述电感线圈的铁氧体磁芯;以及
至少一个电路元件被布线穿过一个形成于所述基板中的导通孔;以及
所述印刷电路装置是可植入传感器装置的一个元件,所述可植入传感器装置能在活生物体内执行分析物的定量测量。
2.一种荧光传感器装置,包括:
光源,其用于将光线导入与介质相互作用的荧光指示剂中;
光电探测器,其用于响应导入光线探测由所述荧光指示剂发射的光线和用于输出与所述探测光线成比例的信号,所述荧光指示剂的响应根据所述介质中的分析物的存在与否和数量而变化;
线圈,其用于从外部电源接收电能和用于将所述信号传输给外部处理装置;以及
基板,其包括电路元件部分和与电路元件部分分开的线圈部分,并且所述基板主要由铁氧体材料形成,所述光源和所述光电探测器安装在所述基板的所述电路元件部分上,并且所述线圈形成为环绕所述基板的所述线圈部分,从而所述铁氧体材料可增强 所述线圈的电感特性;
其中,至少一个电路元件被布线穿过一个形成于所述基板中的导通孔。
3.如权利要求2所述的荧光传感器装置,其特征在于,所述线圈环绕着所述基板的相反表面延伸。
4.如权利要求2所述的荧光传感器装置,其特征在于,被布线穿过形成于所述基板中的导通孔的所述至少一个电路元件是所述光源的元件。
5.如权利要求2所述的荧光传感器装置,其特征在于,所述线圈被边缘缠绕到所述基板的周围。
6.如权利要求2所述的荧光传感器装置,其特征在于,所述线圈用于与外部装置进行数据信号通信。
7.如权利要求2所述的荧光传感器装置,其特征在于,所述线圈用于以电感方式从外部电源接收电能。
8.如权利要求2所述的荧光传感器装置,其特征在于,所述装置包括一个可植入传感器装置,所述可植入传感器装置在生物体内执行分析物的定量测量。
9.如权利要求2所述的荧光传感器装置,其特征在于,所述装置包括一个可植入传感器装置,所述可植入传感器装置在生物体内执行分析物的定性测量。
10.如权利要求8所述的荧光传感器装置,其特征在于,所述光源包括一个发光二极管,并且所述基板还包括至少一个光电探测器。
11.一种荧光传感器装置,包括:
光源,其用于将光线导入与介质相互作用的荧光指示剂中;
光电探测器,其用于响应导入光线探测由所述荧光指示剂发射的光线和用于输出与所述探测光线成比例的信号,所述荧光指示剂的响应根据所述介质中的分析物的存在与否和数量而变化;以及
基板,其上安装着所述光源和所述光电探测器,所述基板包括电路元件部分和与电路元件部分分开的线圈部分;
环绕所述基板的所述线圈部分形成的线圈;以及
其中,一个滤光片位于所述光电探测器的正上方;
至少一个电路元件被布线穿过一个形成于所述基板中的导通孔。
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Families Citing this family (176)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6391005B1 (en) * | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US8337419B2 (en) * | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7041068B2 (en) | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US7749174B2 (en) | 2001-06-12 | 2010-07-06 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge |
WO2002100460A2 (en) | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Electric lancet actuator |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
JP4209767B2 (ja) * | 2001-06-12 | 2009-01-14 | ペリカン テクノロジーズ インコーポレイテッド | 皮膚の性状の一時的変化に対する適応手段を備えた自動最適化形切開器具 |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7708701B2 (en) | 2002-04-19 | 2010-05-04 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device |
US9314194B2 (en) * | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US7297122B2 (en) * | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7175642B2 (en) | 2002-04-19 | 2007-02-13 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7648468B2 (en) * | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8372016B2 (en) * | 2002-04-19 | 2013-02-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling and analyte sensing |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US7901362B2 (en) * | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7547287B2 (en) * | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
AU2003287735A1 (en) | 2002-11-12 | 2004-06-03 | Argose, Inc. | Non-invasive measurement of analytes |
US20040106163A1 (en) * | 2002-11-12 | 2004-06-03 | Workman Jerome James | Non-invasive measurement of analytes |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
EP1578262A4 (en) | 2002-12-31 | 2007-12-05 | Therasense Inc | CONTINUOUS BLOOD SUGAR MONITORING SYSTEM AND USE METHOD |
BRPI0409435A (pt) * | 2003-04-15 | 2006-04-18 | Sensors For Med & Science Inc | dispositivo de circuito impresso com antena integrada e sistema de processamento de sensor implantável com antena de placa de circuito impresso integrada |
US20070032812A1 (en) * | 2003-05-02 | 2007-02-08 | Pelikan Technologies, Inc. | Method and apparatus for a tissue penetrating device user interface |
WO2004107975A2 (en) | 2003-05-30 | 2004-12-16 | Pelikan Technologies, Inc. | Method and apparatus for fluid injection |
WO2004107964A2 (en) | 2003-06-06 | 2004-12-16 | Pelikan Technologies, Inc. | Blood harvesting device with electronic control |
US8066639B2 (en) | 2003-06-10 | 2011-11-29 | Abbott Diabetes Care Inc. | Glucose measuring device for use in personal area network |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US8282576B2 (en) | 2003-09-29 | 2012-10-09 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for an improved sample capture device |
US9351680B2 (en) | 2003-10-14 | 2016-05-31 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a variable user interface |
US8029765B2 (en) * | 2003-12-24 | 2011-10-04 | Masimo Laboratories, Inc. | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
EP1706026B1 (en) | 2003-12-31 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Method and apparatus for improving fluidic flow and sample capture |
WO2005089103A2 (en) | 2004-02-17 | 2005-09-29 | Therasense, Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
US20050234316A1 (en) * | 2004-04-16 | 2005-10-20 | Sensors For Medicine And Science, Inc. | Housing for a circuit that is to be implanted in-vivo and process of making the same |
US7375347B2 (en) * | 2004-04-26 | 2008-05-20 | Sensors For Medicine And Science, Inc. | Systems and methods for extending the useful life of optical sensors |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
EP1765194A4 (en) | 2004-06-03 | 2010-09-29 | Pelikan Technologies Inc | METHOD AND APPARATUS FOR MANUFACTURING A DEVICE FOR SAMPLING LIQUIDS |
US9775553B2 (en) | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US7334067B2 (en) * | 2004-06-03 | 2008-02-19 | Sp Controls, Inc. | Programmable controller having reduced control key set |
US7713574B2 (en) | 2004-07-13 | 2010-05-11 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
US20060167382A1 (en) * | 2004-12-30 | 2006-07-27 | Ajay Deshmukh | Method and apparatus for storing an analyte sampling and measurement device |
WO2006085087A2 (en) * | 2005-02-11 | 2006-08-17 | The University Court Of The University Of Glasgow | Sensing device, apparatus and system, and method for operating the same |
US7308292B2 (en) * | 2005-04-15 | 2007-12-11 | Sensors For Medicine And Science, Inc. | Optical-based sensing devices |
US7233711B1 (en) * | 2005-05-11 | 2007-06-19 | Hewlett Packard Development Company, L.P. | Autonomous evanescent optical nanosensor |
CA2609430A1 (en) * | 2005-06-02 | 2006-12-07 | Glaxo Group Limited | Inductively powered remote oxygen sensor |
EP1943655A2 (en) * | 2005-08-31 | 2008-07-16 | Stratagene California | Compact optical module for fluorescence excitation and detection |
US7705313B1 (en) * | 2005-10-18 | 2010-04-27 | Ric Investments, Llc | Ambient gas compensation in an optical system |
US7766829B2 (en) | 2005-11-04 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
EP2014224A1 (en) * | 2006-03-24 | 2009-01-14 | GlucoTel Scientific Inc. | Telemedical method and device for the calibration of measured values |
US8226891B2 (en) | 2006-03-31 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
US7620438B2 (en) | 2006-03-31 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
US7515822B2 (en) * | 2006-05-12 | 2009-04-07 | Microsoft Corporation | Imaging systems' direct illumination level adjusting method and system involves adjusting operation of image sensor of imaging system based on detected level of ambient illumination |
US8126554B2 (en) | 2006-05-17 | 2012-02-28 | Cardiac Pacemakers, Inc. | Implantable medical device with chemical sensor and related methods |
TWI302043B (en) * | 2006-06-27 | 2008-10-11 | Everlight Electronics Co Ltd | Base structure for ultra-thin light-emitting diode and manufacturing method thereof |
CN101169340B (zh) * | 2006-10-27 | 2010-12-08 | 鸿富锦精密工业(深圳)有限公司 | 主板发光二极管检测装置及方法 |
US20080199894A1 (en) | 2007-02-15 | 2008-08-21 | Abbott Diabetes Care, Inc. | Device and method for automatic data acquisition and/or detection |
JP4488011B2 (ja) * | 2007-02-26 | 2010-06-23 | エプソンイメージングデバイス株式会社 | 電気光学装置、半導体装置、表示装置およびこれを備える電子機器 |
US8123686B2 (en) | 2007-03-01 | 2012-02-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
WO2008130895A2 (en) | 2007-04-14 | 2008-10-30 | Abbott Diabetes Care, Inc. | Method and apparatus for providing dynamic multi-stage signal amplification in a medical device |
US8665091B2 (en) | 2007-05-08 | 2014-03-04 | Abbott Diabetes Care Inc. | Method and device for determining elapsed sensor life |
US7928850B2 (en) | 2007-05-08 | 2011-04-19 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US8456301B2 (en) | 2007-05-08 | 2013-06-04 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US8461985B2 (en) | 2007-05-08 | 2013-06-11 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
JP5680960B2 (ja) | 2007-06-21 | 2015-03-04 | アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. | 健康管理装置および方法 |
US7805174B2 (en) | 2007-09-18 | 2010-09-28 | Cardiac Pacemakers, Inc. | Implantable electro-optical sensor |
US20090247984A1 (en) * | 2007-10-24 | 2009-10-01 | Masimo Laboratories, Inc. | Use of microneedles for small molecule metabolite reporter delivery |
US7907061B2 (en) * | 2007-11-14 | 2011-03-15 | Intersil Americas Inc. | Proximity sensors and methods for sensing proximity |
US8290557B2 (en) * | 2007-12-12 | 2012-10-16 | Medtronic, Inc. | Implantable optical sensor and method for use |
US20090159801A1 (en) * | 2007-12-21 | 2009-06-25 | Newport Corporation | Fluorescence optical coatings and methods for producing same |
US20090209883A1 (en) * | 2008-01-17 | 2009-08-20 | Michael Higgins | Tissue penetrating apparatus |
EP2982383B1 (en) | 2008-04-10 | 2019-05-15 | Abbott Diabetes Care, Inc. | Method for sterilizing an analyte sensor |
US9386944B2 (en) * | 2008-04-11 | 2016-07-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte detecting device |
US20090294277A1 (en) * | 2008-05-30 | 2009-12-03 | Abbott Diabetes Care, Inc. | Method and system for producing thin film biosensors |
US20100004518A1 (en) | 2008-07-03 | 2010-01-07 | Masimo Laboratories, Inc. | Heat sink for noninvasive medical sensor |
US8630691B2 (en) | 2008-08-04 | 2014-01-14 | Cercacor Laboratories, Inc. | Multi-stream sensor front ends for noninvasive measurement of blood constituents |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
US9402544B2 (en) | 2009-02-03 | 2016-08-02 | Abbott Diabetes Care Inc. | Analyte sensor and apparatus for insertion of the sensor |
EP2221606A3 (en) | 2009-02-11 | 2012-06-06 | Samsung Electronics Co., Ltd. | Integrated bio-chip and method of fabricating the integrated bio-chip |
US7935935B2 (en) * | 2009-02-27 | 2011-05-03 | Medtronic, Inc. | Radiation-based timer for implantable medical devices |
US9226701B2 (en) | 2009-04-28 | 2016-01-05 | Abbott Diabetes Care Inc. | Error detection in critical repeating data in a wireless sensor system |
US9184490B2 (en) | 2009-05-29 | 2015-11-10 | Abbott Diabetes Care Inc. | Medical device antenna systems having external antenna configurations |
US8993331B2 (en) | 2009-08-31 | 2015-03-31 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods for managing power and noise |
WO2011026147A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Diabetes Care Inc. | Analyte signal processing device and methods |
CN102473276B (zh) | 2009-08-31 | 2016-04-13 | 雅培糖尿病护理公司 | 医疗装置及方法 |
EP3360479B1 (en) | 2010-01-21 | 2019-12-18 | ARKRAY, Inc. | Electric power supply method |
JP5663900B2 (ja) | 2010-03-05 | 2015-02-04 | セイコーエプソン株式会社 | 分光センサー装置及び電子機器 |
WO2011111008A1 (en) | 2010-03-11 | 2011-09-15 | Ecole Polytechnique Federale De Lausanne (Epfl) | Telemetry system for sensing applications in lossy media |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
JP5701528B2 (ja) | 2010-07-16 | 2015-04-15 | オリンパス株式会社 | 生体状態量測定装置 |
EP2680754B1 (en) | 2011-02-28 | 2019-04-24 | Abbott Diabetes Care, Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
US8779349B2 (en) * | 2011-03-08 | 2014-07-15 | Fluke Corporation | Minimizing ambient light in a feedback circuit in pulse oximeter test instruments |
KR101959067B1 (ko) | 2011-03-15 | 2019-03-15 | 센세오닉스, 인코포레이티드 | 산화 민감성 물질의 통합된 촉매적 보호 |
JP5862025B2 (ja) * | 2011-03-16 | 2016-02-16 | セイコーエプソン株式会社 | 光学センサー及び電子機器 |
MX346099B (es) | 2011-10-11 | 2017-03-07 | Senseonics Inc | Sistema para activar la fuerza de un campo electrodinámico. |
US9069536B2 (en) | 2011-10-31 | 2015-06-30 | Abbott Diabetes Care Inc. | Electronic devices having integrated reset systems and methods thereof |
CA2840640C (en) | 2011-11-07 | 2020-03-24 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods |
US9693714B2 (en) | 2012-02-10 | 2017-07-04 | Senseonics, Incorporated | Digital ASIC sensor platform |
WO2013147799A1 (en) | 2012-03-29 | 2013-10-03 | Advanced Bionics Ag | Implantable antenna assemblies |
WO2013163298A1 (en) * | 2012-04-24 | 2013-10-31 | Senseonics, Incorporated | Angle of incidence selective band pass filter for implantable chemical sensor |
US9968306B2 (en) | 2012-09-17 | 2018-05-15 | Abbott Diabetes Care Inc. | Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems |
CN103411634A (zh) * | 2012-11-28 | 2013-11-27 | 上海兰宝传感科技股份有限公司 | 智能型背景抑制光电传感器 |
MX2015007315A (es) | 2012-12-13 | 2016-03-31 | California Inst Of Techn | Fabricacion de electrodos tridimensionales de area superficial alta. |
KR20150100908A (ko) | 2012-12-28 | 2015-09-02 | 센세오닉스, 인코포레이티드 | 산화 및 광 안정성을 위한 분석물 투과형 멤브레인 시스템 |
US11109779B2 (en) | 2012-12-28 | 2021-09-07 | Senseonics, Incorporated | Chemical modification of analyte permeable membrane for enhanced oxidative stability |
RU2015129811A (ru) * | 2013-02-06 | 2017-03-13 | Кэлифорниа Инститьют Оф Текнолоджи | Миниатюризированные имплантируемые электрохимические сенсорные устройства |
WO2014144514A2 (en) * | 2013-03-15 | 2014-09-18 | Senseonics, Incorporated | Improved implantation and antenna orientation of an implantable sensor |
CN104055492A (zh) * | 2013-03-18 | 2014-09-24 | 精工爱普生株式会社 | 电子设备 |
WO2014179343A1 (en) | 2013-04-30 | 2014-11-06 | Abbott Diabetes Care Inc. | Systems, devices, and methods for energy efficient electrical device activation |
WO2015013552A1 (en) * | 2013-07-24 | 2015-01-29 | California Institute Of Technology | Design and fabrication of implantable fully integrated electrochemical sensors |
CA2922095C (en) | 2013-08-21 | 2021-12-28 | Senseonics, Incorporated | Drug elution for in vivo protection of bio-sensing analytes |
US9963556B2 (en) | 2013-09-18 | 2018-05-08 | Senseonics, Incorporated | Critical point drying of hydrogels in analyte sensors |
CN103479363B (zh) * | 2013-09-30 | 2015-03-18 | 深圳市倍轻松科技股份有限公司 | 血液中血氧饱和度的测量方法及系统 |
WO2015065442A1 (en) | 2013-10-31 | 2015-05-07 | Advanced Bionics Ag | Headpieces and implantable cochlear stimulation systems including the same |
WO2015073876A1 (en) * | 2013-11-15 | 2015-05-21 | Senseonics, Incorporated | Fluorescence-based sensor with multiple indicator grafts |
JP2017508630A (ja) * | 2013-12-31 | 2017-03-30 | キヤノン ユー.エス. ライフ サイエンシズ, インコーポレイテッドCanon U.S. Life Sciences, Inc. | 積層マイクロ流体デバイスのプリント回路基板設計 |
US10872048B2 (en) | 2014-01-13 | 2020-12-22 | Senseonics, Incorporated | Remotely-powered sensing system with multiple sensing devices |
CN105813565B (zh) * | 2014-04-03 | 2017-11-03 | 皇家飞利浦有限公司 | 用于补偿生命体征监测中的非线性效应的监测设备和方法 |
CN106604676A (zh) * | 2014-07-15 | 2017-04-26 | 传感技术股份有限公司 | 用于分析物传感器的对于高入射角度的光具有低敏感度的集成滤光器系统 |
US9814413B2 (en) | 2014-07-24 | 2017-11-14 | Thomas Jefferson University | Long-term implantable monitoring system and methods of use |
KR20160040746A (ko) * | 2014-09-26 | 2016-04-15 | 에브리봇 주식회사 | 먼지 센서, 먼지 측정 장치, 로봇 청소기 및 그들의 제어 방법 |
ES2923584T3 (es) | 2015-02-24 | 2022-09-28 | Hayward Ind Inc | Limpiafondos con detección óptica fuera del agua y de residuos |
CN107529989B (zh) * | 2015-04-14 | 2023-08-04 | 皇家飞利浦有限公司 | 血管内装置、系统和形成方法 |
EP3087916B1 (en) * | 2015-04-28 | 2023-09-20 | Nokia Technologies Oy | Physiological measurement sensor |
KR101686633B1 (ko) * | 2015-05-18 | 2016-12-14 | 주식회사 아이티엠반도체 | 안테나 모듈 패키지 및 그 제조방법 |
US10716500B2 (en) | 2015-06-29 | 2020-07-21 | Cardiac Pacemakers, Inc. | Systems and methods for normalization of chemical sensor data based on fluid state changes |
US10448871B2 (en) | 2015-07-02 | 2019-10-22 | Masimo Corporation | Advanced pulse oximetry sensor |
US10368788B2 (en) | 2015-07-23 | 2019-08-06 | California Institute Of Technology | System and methods for wireless drug delivery on command |
CA2992707C (en) * | 2015-07-24 | 2020-01-21 | Zevex, Inc. | Magnetic pressure sensing system for an infusion pump |
DE102015117265A1 (de) * | 2015-10-09 | 2017-04-13 | Endress+Hauser Conducta Gmbh+Co. Kg | Vorrichtung zur Überwachung einer Lichtquelle eines optischen Sensors |
US9615427B1 (en) * | 2015-11-30 | 2017-04-04 | Texas Instruments Incorporated | Exploiting constructive interference from ambient conditions |
WO2017173339A1 (en) * | 2016-04-01 | 2017-10-05 | The Board Of Trustees Of The University Of Illinois | Implantable medical devices for optogenetics |
US20170290535A1 (en) * | 2016-04-08 | 2017-10-12 | Medtronic Minimed, Inc. | Analyte sensor with indicators |
US10984519B2 (en) * | 2016-08-03 | 2021-04-20 | Panduit Corp. | Method for evaluating the optical insertion loss of a mechanical splice joint of two optical fibers |
US10367252B2 (en) * | 2016-08-11 | 2019-07-30 | Apple Inc. | Broadband antenna |
CN109561860A (zh) * | 2016-08-12 | 2019-04-02 | 皇家飞利浦有限公司 | 传感器设备和方法、用于与传感器设备通信的设备和方法 |
DE102016115607A1 (de) * | 2016-08-23 | 2018-03-01 | B. Braun Melsungen Ag | Messsystem mit verringertem Übersprechen zur Messung von Fluidparametern |
WO2018184012A1 (en) | 2017-03-31 | 2018-10-04 | Capillary Biomedical, Inc. | Helical insertion infusion device |
CN108968976B (zh) | 2017-05-31 | 2022-09-13 | 心脏起搏器股份公司 | 具有化学传感器的植入式医疗设备 |
US12064209B2 (en) | 2017-06-30 | 2024-08-20 | Integrated Medical Sensors, Inc. | Wireless sensing platform for multi-analyte sensing |
US12004853B2 (en) | 2017-07-26 | 2024-06-11 | Cardiac Pacemakers, Inc. | Systems and methods for disambiguation of posture |
CN109381195B (zh) | 2017-08-10 | 2023-01-10 | 心脏起搏器股份公司 | 包括电解质传感器融合的系统和方法 |
CN109419515B (zh) | 2017-08-23 | 2023-03-24 | 心脏起搏器股份公司 | 具有分级激活的可植入化学传感器 |
JP7026337B2 (ja) * | 2017-08-29 | 2022-02-28 | パナソニックIpマネジメント株式会社 | 光観測装置 |
CN109864746B (zh) | 2017-12-01 | 2023-09-29 | 心脏起搏器股份公司 | 用于医学装置的多模式分析物传感器 |
CN109864747B (zh) | 2017-12-05 | 2023-08-25 | 心脏起搏器股份公司 | 多模式分析物传感器光电子接口 |
CN108254158B (zh) * | 2018-01-12 | 2019-09-24 | 深圳奥比中光科技有限公司 | 一种监测光学元件完整性的装置及方法 |
JP2019136442A (ja) * | 2018-02-15 | 2019-08-22 | セイコーエプソン株式会社 | 生体情報測定装置 |
CN108469300B (zh) * | 2018-03-14 | 2021-01-29 | 业成科技(成都)有限公司 | 环境感光孔封装结构及其制造方法 |
CN108896184B (zh) * | 2018-07-10 | 2020-12-25 | 张洋 | 颜色识别方法 |
CN108844634A (zh) * | 2018-07-10 | 2018-11-20 | 张洋 | 颜色识别方法 |
CA3157995A1 (en) | 2019-10-25 | 2021-04-29 | Cercacor Laboratories, Inc. | Indicator compounds, devices comprising indicator compounds, and methods of making and using the same |
US11940331B2 (en) | 2020-02-05 | 2024-03-26 | Analog Devices, Inc. | Packages for wireless temperature sensor nodes |
CN114271783B (zh) * | 2020-09-27 | 2024-01-30 | 北京小米移动软件有限公司 | 皮肤检测装置、方法和终端 |
CN112787095B (zh) * | 2021-01-20 | 2024-03-01 | 深圳新源柔性科技有限公司 | 一种集成天线及其制造方法、一种集成电子器件 |
CA3229869A1 (en) | 2021-09-01 | 2023-03-09 | Integrated Medical Sensors, Inc. | Wired implantable monolithic integrated sensor circuit |
WO2024106370A1 (ja) * | 2022-11-14 | 2024-05-23 | 株式会社村田製作所 | Rfidモジュール |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1328638A (zh) * | 1998-08-26 | 2001-12-26 | 医药及科学传感器公司 | 基于光学的感测装置 |
US6400974B1 (en) * | 2000-06-29 | 2002-06-04 | Sensors For Medicine And Science, Inc. | Implanted sensor processing system and method for processing implanted sensor output |
US6402689B1 (en) * | 1998-09-30 | 2002-06-11 | Sicel Technologies, Inc. | Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors |
CN1375716A (zh) * | 2002-04-23 | 2002-10-23 | 上海交通大学 | 电磁型微机械阵列光开关 |
Family Cites Families (140)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1909936B1 (de) * | 1969-02-27 | 1970-06-04 | Philips Patentverwaltung | Integriertes Mikrowellensystem mit einem Substrat aus nicht-magnetischem keramischem Material und Verfahren zur Herstellung derartiger Substrate |
JPS5599843A (en) * | 1979-01-25 | 1980-07-30 | Tdk Corp | Reception unit |
JPS59189212U (ja) * | 1983-05-18 | 1984-12-15 | 株式会社村田製作所 | チツプ型インダクタ |
US4952035A (en) * | 1985-03-22 | 1990-08-28 | Canon Kabushiki Kaisha | Optical element and device using same |
US5001054A (en) * | 1986-06-26 | 1991-03-19 | Becton, Dickinson And Company | Method for monitoring glucose |
JPS6326109A (ja) * | 1986-07-18 | 1988-02-03 | Nec Corp | ラインフイルタ− |
US5003622A (en) * | 1989-09-26 | 1991-03-26 | Astec International Limited | Printed circuit transformer |
US6040194A (en) * | 1989-12-14 | 2000-03-21 | Sensor Technologies, Inc. | Methods and device for detecting and quantifying substances in body fluids |
US5244810A (en) * | 1990-01-12 | 1993-09-14 | Gottlieb Amos J | Analytical method |
JP2741090B2 (ja) * | 1990-03-23 | 1998-04-15 | キヤノン株式会社 | プリント基板 |
CN2078903U (zh) * | 1990-11-07 | 1991-06-12 | 宋松源 | 学习姿势与光照度自动监测器 |
US5117825A (en) * | 1990-11-09 | 1992-06-02 | John Grevious | Closed loop transmitter for medical implant |
US5126714A (en) * | 1990-12-20 | 1992-06-30 | The United States Of America As Represented By The Secretary Of The Navy | Integrated circuit transformer |
JPH04348258A (ja) * | 1991-05-27 | 1992-12-03 | Kowa Co | 多チャンネル光学測定装置 |
US5300911A (en) * | 1991-07-10 | 1994-04-05 | International Business Machines Corporation | Monolithic magnetic device with printed circuit interconnections |
US5302393A (en) * | 1991-07-11 | 1994-04-12 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor |
NL9200207A (nl) | 1992-02-05 | 1993-09-01 | Nedap Nv | Implanteerbare biomedische sensorinrichting, in het bijzonder voor meting van de glucoseconcentratie. |
JPH06129985A (ja) * | 1992-10-19 | 1994-05-13 | Seibutsukei Tokutei Sangyo Gijutsu Kenkyu Suishin Kiko | 青果物内部品質判定装置 |
US5368224A (en) * | 1992-10-23 | 1994-11-29 | Nellcor Incorporated | Method for reducing ambient noise effects in electronic monitoring instruments |
US5341805A (en) * | 1993-04-06 | 1994-08-30 | Cedars-Sinai Medical Center | Glucose fluorescence monitor and method |
US5672881A (en) * | 1994-09-14 | 1997-09-30 | Glyko, Inc. | Charge-coupled device imaging apparatus |
JPH08107019A (ja) * | 1994-10-03 | 1996-04-23 | Tdk Corp | コイル素子及びその製造方法 |
US5541567A (en) * | 1994-10-17 | 1996-07-30 | International Business Machines Corporation | Coaxial vias in an electronic substrate |
JP3359435B2 (ja) * | 1994-11-04 | 2002-12-24 | 株式会社山武 | タッチキー |
JPH08145889A (ja) * | 1994-11-21 | 1996-06-07 | Shimadzu Corp | 蛍光測定装置 |
JPH08166446A (ja) * | 1994-12-13 | 1996-06-25 | Kubota Corp | トランスポンダ |
US5517313A (en) | 1995-02-21 | 1996-05-14 | Colvin, Jr.; Arthur E. | Fluorescent optical sensor |
US5584870A (en) * | 1995-03-09 | 1996-12-17 | Cochlear Ltd. | Implant ESD protection network |
US5628310A (en) * | 1995-05-19 | 1997-05-13 | Joseph R. Lakowicz | Method and apparatus to perform trans-cutaneous analyte monitoring |
US5995860A (en) * | 1995-07-06 | 1999-11-30 | Thomas Jefferson University | Implantable sensor and system for measurement and control of blood constituent levels |
US5720771A (en) * | 1995-08-02 | 1998-02-24 | Pacesetter, Inc. | Method and apparatus for monitoring physiological data from an implantable medical device |
US5704352A (en) * | 1995-11-22 | 1998-01-06 | Tremblay; Gerald F. | Implantable passive bio-sensor |
US6002954A (en) * | 1995-11-22 | 1999-12-14 | The Regents Of The University Of California | Detection of biological molecules using boronate-based chemical amplification and optical sensors |
US5833496A (en) * | 1996-02-22 | 1998-11-10 | Omega Engineering, Inc. | Connector with protection from electromagnetic emissions |
US5801684A (en) * | 1996-02-29 | 1998-09-01 | Motorola, Inc. | Electronic device with display and display driver and method of operation of a display driver |
WO1997032629A1 (en) * | 1996-03-06 | 1997-09-12 | Advanced Bionics Corporation | Magnetless implantable stimulator and external transmitter and implant tools for aligning same |
US5833603A (en) * | 1996-03-13 | 1998-11-10 | Lipomatrix, Inc. | Implantable biosensing transponder |
US6143432A (en) * | 1998-01-09 | 2000-11-07 | L. Pierre deRochemont | Ceramic composites with improved interfacial properties and methods to make such composites |
SG54559A1 (en) * | 1996-09-13 | 1998-11-16 | Hitachi Ltd | Power transmission system ic card and information communication system using ic card |
JPH1090405A (ja) * | 1996-09-19 | 1998-04-10 | Toshiba Corp | 情報処理装置 |
US5963132A (en) * | 1996-10-11 | 1999-10-05 | Avid Indentification Systems, Inc. | Encapsulated implantable transponder |
JP3692666B2 (ja) * | 1996-11-22 | 2005-09-07 | 東ソー株式会社 | 蛍光検出装置 |
JPH10206331A (ja) * | 1997-01-24 | 1998-08-07 | Tosoh Corp | 螢光検出器及び液体クロマトグラフィー装置 |
JP3654325B2 (ja) * | 1997-02-13 | 2005-06-02 | 富士写真フイルム株式会社 | 蛍光検出装置 |
JPH10233469A (ja) * | 1997-02-18 | 1998-09-02 | Taiyo Yuden Co Ltd | 半導体装置 |
US6164284A (en) * | 1997-02-26 | 2000-12-26 | Schulman; Joseph H. | System of implantable devices for monitoring and/or affecting body parameters |
JP2988421B2 (ja) * | 1997-03-24 | 1999-12-13 | 日本電気株式会社 | Emi抑制多層プリント基板 |
US5894351A (en) * | 1997-05-13 | 1999-04-13 | Colvin, Jr.; Arthur E. | Fluorescence sensing device |
US6419624B1 (en) * | 1999-10-11 | 2002-07-16 | Uromedica, Inc. | Apparatus and method for inserting an adjustable implantable genitourinary device |
US5984875A (en) * | 1997-08-22 | 1999-11-16 | Innotek Pet Products, Inc. | Ingestible animal temperature sensor |
US6731976B2 (en) * | 1997-09-03 | 2004-05-04 | Medtronic, Inc. | Device and method to measure and communicate body parameters |
US6259937B1 (en) * | 1997-09-12 | 2001-07-10 | Alfred E. Mann Foundation | Implantable substrate sensor |
US6976626B2 (en) * | 1997-09-16 | 2005-12-20 | Metrologic Instruments, Inc. | Wireless bar code symbol driven portable data terminal (PDT) system adapted for single handed operation |
JPH11108841A (ja) | 1997-09-30 | 1999-04-23 | Shimadzu Corp | 蛍光測定装置 |
US6268161B1 (en) * | 1997-09-30 | 2001-07-31 | M-Biotech, Inc. | Biosensor |
US6585763B1 (en) * | 1997-10-14 | 2003-07-01 | Vascusense, Inc. | Implantable therapeutic device and method |
US6088608A (en) * | 1997-10-20 | 2000-07-11 | Alfred E. Mann Foundation | Electrochemical sensor and integrity tests therefor |
US6305602B1 (en) * | 1997-12-01 | 2001-10-23 | Diebold, Incorporated | Light monitoring system and method for automated transaction machine |
JP3716088B2 (ja) * | 1997-12-08 | 2005-11-16 | 京セラ株式会社 | 配線基板 |
JPH11176675A (ja) * | 1997-12-09 | 1999-07-02 | Tokin Corp | 小型非接触伝送装置 |
JPH11176672A (ja) * | 1997-12-10 | 1999-07-02 | Tokin Corp | 小型非接触伝送装置 |
US6289229B1 (en) * | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
US6009878A (en) * | 1998-02-02 | 2000-01-04 | Medtronic, Inc. | System for locating implantable medical device |
US6394952B1 (en) * | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
US6267722B1 (en) * | 1998-02-03 | 2001-07-31 | Adeza Biomedical Corporation | Point of care diagnostic systems |
US6058330A (en) * | 1998-03-06 | 2000-05-02 | Dew Engineering And Development Limited | Transcutaneous energy transfer device |
DE19811017A1 (de) * | 1998-03-13 | 1999-09-16 | Dade Behring Marburg Gmbh | Neues Verfahren zur Bestimmung von Plasmaproteinen und Faktoren der Hämostase sowie ein neues, implantierbares Meßgerät |
DE19861428B4 (de) * | 1998-03-17 | 2008-01-10 | Robert Bosch Gmbh | Optischer Sensor |
US6505059B1 (en) * | 1998-04-06 | 2003-01-07 | The General Hospital Corporation | Non-invasive tissue glucose level monitoring |
US6015386A (en) * | 1998-05-07 | 2000-01-18 | Bpm Devices, Inc. | System including an implantable device and methods of use for determining blood pressure and other blood parameters of a living being |
GB9816011D0 (en) * | 1998-07-22 | 1998-09-23 | Habib Nagy A | Monitoring treatment using implantable telemetric sensors |
US6084665A (en) * | 1998-09-01 | 2000-07-04 | Honeywell International Inc. | Optical sensor for detecting the dew point of an atmosphere |
US6212431B1 (en) * | 1998-09-08 | 2001-04-03 | Advanced Bionics Corporation | Power transfer circuit for implanted devices |
US6491647B1 (en) * | 1998-09-23 | 2002-12-10 | Active Signal Technologies, Inc. | Physiological sensing device |
DK1867275T3 (da) * | 1998-09-30 | 2011-04-04 | Sicel Technologies Inc | Systemer med implanterbare aooarater til dynamisk overvågning af tumorer |
US6201980B1 (en) * | 1998-10-05 | 2001-03-13 | The Regents Of The University Of California | Implantable medical sensor system |
US6687515B1 (en) * | 1998-10-07 | 2004-02-03 | Denso Corporation | Wireless video telephone with ambient light sensor |
EP2229879A1 (en) * | 1998-10-08 | 2010-09-22 | Medtronic MiniMed, Inc. | Telemetered characteristic monitor system |
US6073050A (en) * | 1998-11-10 | 2000-06-06 | Advanced Bionics Corporation | Efficient integrated RF telemetry transmitter for use with implantable device |
WO2000038570A1 (en) * | 1998-12-31 | 2000-07-06 | Ball Semiconductor, Inc. | Miniature implanted orthopedic sensors |
US6424847B1 (en) * | 1999-02-25 | 2002-07-23 | Medtronic Minimed, Inc. | Glucose monitor calibration methods |
US7577469B1 (en) * | 1999-03-11 | 2009-08-18 | Jack L. Aronowitz | Noninvasive transdermal systems for detecting an analyte in a biological fluid and methods |
US6092530A (en) * | 1999-03-24 | 2000-07-25 | The B.F. Goodrich Company | Remotely interrogated implant device with sensor for detecting accretion of biological matter |
US6475750B1 (en) * | 1999-05-11 | 2002-11-05 | M-Biotech, Inc. | Glucose biosensor |
DE19929328A1 (de) * | 1999-06-26 | 2001-01-04 | Daimlerchrysler Aerospace Ag | Vorrichtung zur medizinischen Langzeitüberwachung von Personen |
US6163377A (en) * | 1999-07-23 | 2000-12-19 | Cv Us, Inc. | Colorimeter |
US6802811B1 (en) * | 1999-09-17 | 2004-10-12 | Endoluminal Therapeutics, Inc. | Sensing, interrogating, storing, telemetering and responding medical implants |
US6368275B1 (en) * | 1999-10-07 | 2002-04-09 | Acuson Corporation | Method and apparatus for diagnostic medical information gathering, hyperthermia treatment, or directed gene therapy |
US6442434B1 (en) * | 1999-10-19 | 2002-08-27 | Abiomed, Inc. | Methods and apparatus for providing a sufficiently stable power to a load in an energy transfer system |
US6411108B1 (en) * | 1999-11-05 | 2002-06-25 | Sensor Technologies, Inc. | Noncontact signal analyzer |
EP2259569B1 (en) | 1999-11-08 | 2012-06-06 | Casio Computer Co., Ltd. | Photosensor system and drive control method thereof |
JP3455761B2 (ja) | 1999-11-10 | 2003-10-14 | カシオ計算機株式会社 | フォトセンサシステムの感度調整装置及びその感度調整方法 |
FR2802738A1 (fr) * | 1999-12-15 | 2001-06-22 | Circe | Dispositif de lecture de transpondeur |
US6400338B1 (en) | 2000-01-11 | 2002-06-04 | Destron-Fearing Corporation | Passive integrated transponder tag with unitary antenna core |
US6415186B1 (en) * | 2000-01-14 | 2002-07-02 | Advanced Bionics Corporation | Active feed forward power control loop |
US20020016535A1 (en) * | 2000-01-28 | 2002-02-07 | Martin W. Blake | Subcutaneous glucose measurement device |
US6895263B2 (en) * | 2000-02-23 | 2005-05-17 | Medtronic Minimed, Inc. | Real time self-adjusting calibration algorithm |
DE10011284B4 (de) * | 2000-03-08 | 2007-06-28 | Disetronic Licensing Ag | Vorrichtung für eine In-vivo Messung der Konzentration eines Inhaltsstoffs einer Körperflüssigkeit |
US20020043651A1 (en) * | 2000-04-04 | 2002-04-18 | Darrow Christopher B. | Fluorescent lifetime assays for non-invasive quantification of analytes such as glucose |
JP2001308227A (ja) * | 2000-04-21 | 2001-11-02 | Mitsui Chemicals Inc | 電子回路基板用複合材料 |
IL143418A (en) * | 2000-05-31 | 2004-09-27 | Given Imaging Ltd | Measurement of electrical properties of tissue |
US20020032435A1 (en) * | 2000-06-20 | 2002-03-14 | Levin Bruce H. | Tracking surgical implements with integrated circuits |
US20020019707A1 (en) * | 2000-06-26 | 2002-02-14 | Cohen Alan M. | Glucose metering system |
US20030169169A1 (en) * | 2000-08-17 | 2003-09-11 | Luc Wuidart | Antenna generating an electromagnetic field for transponder |
JP2002082048A (ja) * | 2000-09-07 | 2002-03-22 | Shimadzu Corp | 非接触式物性測定方法およびその装置 |
US6443891B1 (en) * | 2000-09-20 | 2002-09-03 | Medtronic, Inc. | Telemetry modulation protocol system for medical devices |
IL138683A0 (en) | 2000-09-25 | 2001-10-31 | Vital Medical Ltd | Apparatus and method for monitoring tissue vitality parameters |
GB0025147D0 (en) * | 2000-10-13 | 2000-11-29 | Torsana Diabetes Diagnostics A | Optical sensor for in situ measurement of analytes |
US6421015B1 (en) * | 2001-01-02 | 2002-07-16 | Auden Techno Corp | Planar helix antenna with two frequencies |
US6666821B2 (en) * | 2001-01-08 | 2003-12-23 | Medtronic, Inc. | Sensor system |
US6542777B1 (en) * | 2001-01-19 | 2003-04-01 | Advanced Bionics Corporation | Spiral shield for a flexible high-Q implantable inductively coupled device |
US20040133092A1 (en) * | 2001-03-27 | 2004-07-08 | Kain Aron Z. | Wireless system for measuring distension in flexible tubes |
US6694158B2 (en) * | 2001-04-11 | 2004-02-17 | Motorola, Inc. | System using a portable detection device for detection of an analyte through body tissue |
US6454710B1 (en) * | 2001-04-11 | 2002-09-24 | Motorola, Inc. | Devices and methods for monitoring an analyte |
US6590497B2 (en) * | 2001-06-29 | 2003-07-08 | Hewlett-Packard Development Company, L.P. | Light sensing hidden object location system |
US6456256B1 (en) * | 2001-08-03 | 2002-09-24 | Cardiac Pacemakers, Inc. | Circumferential antenna for an implantable medical device |
DE10139707A1 (de) * | 2001-08-11 | 2003-02-20 | Philips Corp Intellectual Pty | Leiterplatte |
US7323141B2 (en) * | 2001-08-13 | 2008-01-29 | Bayer Healthcare Llc | Button layout for a testing instrument |
JP2003057111A (ja) * | 2001-08-20 | 2003-02-26 | Osaka Gas Co Ltd | 火炎センサ |
US6545483B1 (en) * | 2001-08-29 | 2003-04-08 | Sensor Technologies, Inc. | Analyzer sensor |
WO2003100469A2 (en) * | 2001-10-02 | 2003-12-04 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Internal biochemical sensing device |
US6809507B2 (en) * | 2001-10-23 | 2004-10-26 | Medtronic Minimed, Inc. | Implantable sensor electrodes and electronic circuitry |
US6731961B2 (en) * | 2001-11-09 | 2004-05-04 | Optiscan Biomedical Corp. | Method for transforming phase spectra to absorption spectra |
US6682490B2 (en) * | 2001-12-03 | 2004-01-27 | The Cleveland Clinic Foundation | Apparatus and method for monitoring a condition inside a body cavity |
US20030113934A1 (en) * | 2001-12-17 | 2003-06-19 | Sung-Yun Kwon | Diagnostic sensing apparatus |
CN1156685C (zh) * | 2001-12-26 | 2004-07-07 | 中国科学院上海光学精密机械研究所 | 光纤倏逝波生物传感器 |
US7022072B2 (en) * | 2001-12-27 | 2006-04-04 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US7050855B2 (en) * | 2002-01-29 | 2006-05-23 | Medtronic, Inc. | Medical implantable system for reducing magnetic resonance effects |
EP1474038A1 (en) * | 2002-01-29 | 2004-11-10 | Sicel Technologies, Inc. | Implantable sensor housing and fabrication methods |
US6806552B2 (en) * | 2002-02-21 | 2004-10-19 | Altera, Corp. | Integrated inductive circuits |
US6957107B2 (en) * | 2002-03-13 | 2005-10-18 | Cardionet, Inc. | Method and apparatus for monitoring and communicating with an implanted medical device |
US6864795B2 (en) * | 2002-04-18 | 2005-03-08 | Bed-Check Corporation | Apparatus for lighting a patient monitor front panel |
US7485093B2 (en) * | 2002-04-25 | 2009-02-03 | Given Imaging Ltd. | Device and method for in-vivo sensing |
US7445010B2 (en) * | 2003-01-29 | 2008-11-04 | Torax Medical, Inc. | Use of magnetic implants to treat issue structures |
JP2003325439A (ja) * | 2002-05-15 | 2003-11-18 | Olympus Optical Co Ltd | カプセル型医療装置 |
DE20309539U1 (de) * | 2002-06-20 | 2003-09-04 | Schaffner Emv Ag, Luterbach | Elektronische Schaltung mit integriertem induktiven Bauelement |
US6772011B2 (en) * | 2002-08-20 | 2004-08-03 | Thoratec Corporation | Transmission of information from an implanted medical device |
US7020508B2 (en) * | 2002-08-22 | 2006-03-28 | Bodymedia, Inc. | Apparatus for detecting human physiological and contextual information |
US7134999B2 (en) * | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
BRPI0409435A (pt) * | 2003-04-15 | 2006-04-18 | Sensors For Med & Science Inc | dispositivo de circuito impresso com antena integrada e sistema de processamento de sensor implantável com antena de placa de circuito impresso integrada |
-
2004
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1328638A (zh) * | 1998-08-26 | 2001-12-26 | 医药及科学传感器公司 | 基于光学的感测装置 |
US6402689B1 (en) * | 1998-09-30 | 2002-06-11 | Sicel Technologies, Inc. | Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors |
US6400974B1 (en) * | 2000-06-29 | 2002-06-04 | Sensors For Medicine And Science, Inc. | Implanted sensor processing system and method for processing implanted sensor output |
CN1375716A (zh) * | 2002-04-23 | 2002-10-23 | 上海交通大学 | 电磁型微机械阵列光开关 |
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