JP5415364B2 - センサーに対する周辺光の影響を減じるようになされたセンサー - Google Patents
センサーに対する周辺光の影響を減じるようになされたセンサー Download PDFInfo
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- JP5415364B2 JP5415364B2 JP2010140820A JP2010140820A JP5415364B2 JP 5415364 B2 JP5415364 B2 JP 5415364B2 JP 2010140820 A JP2010140820 A JP 2010140820A JP 2010140820 A JP2010140820 A JP 2010140820A JP 5415364 B2 JP5415364 B2 JP 5415364B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K1/00—Printed circuits
- H05K1/16—Printed circuits incorporating printed electric components, e.g. printed resistor, capacitor, inductor
- H05K1/165—Printed circuits incorporating printed electric components, e.g. printed resistor, capacitor, inductor incorporating printed inductors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/124—Sensitivity
- G01N2201/1244—Ambient light detector, e.g. for invalidating
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K1/00—Printed circuits
- H05K1/02—Details
- H05K1/03—Use of materials for the substrate
- H05K1/0306—Inorganic insulating substrates, e.g. ceramic, glass
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K2201/00—Indexing scheme relating to printed circuits covered by H05K1/00
- H05K2201/08—Magnetic details
- H05K2201/083—Magnetic materials
- H05K2201/086—Magnetic materials for inductive purposes, e.g. printed inductor with ferrite core
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K2201/00—Indexing scheme relating to printed circuits covered by H05K1/00
- H05K2201/09—Shape and layout
- H05K2201/09818—Shape or layout details not covered by a single group of H05K2201/09009 - H05K2201/09809
- H05K2201/09972—Partitioned, e.g. portions of a PCB dedicated to different functions; Boundary lines therefore; Portions of a PCB being processed separately or differently
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K2201/00—Indexing scheme relating to printed circuits covered by H05K1/00
- H05K2201/10—Details of components or other objects attached to or integrated in a printed circuit board
- H05K2201/10007—Types of components
- H05K2201/10106—Light emitting diode [LED]
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K3/00—Apparatus or processes for manufacturing printed circuits
- H05K3/40—Forming printed elements for providing electric connections to or between printed circuits
- H05K3/403—Edge contacts; Windows or holes in the substrate having plural connections on the walls thereof
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Emergency Medicine (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Details Of Aerials (AREA)
- Photometry And Measurement Of Optical Pulse Characteristics (AREA)
- Near-Field Transmission Systems (AREA)
- Optical Communication System (AREA)
Description
Claims (36)
- センサーであって、
ハウジングと、
前記ハウジング内に収容されている回路基板であって、該回路基板を貫通して形成されている第1及び第2の穴を備えており、該第1の穴は前記回路基板の頂面から前記回路基板の底面への第1の通路を形成しており、前記第2の穴は前記回路基板の頂面から前記回路基板の底面への第2の通路を形成しており、迷光が進入しない材料によって作られている前記回路基板と、
前記回路基板の底面に取り付けられた第1及び第2の光検知器であって、各々、光感知面を有しており、前記第1の光検知器の前記光感知面は、前記第1の通路内を進む光が前記第1の光検知器の光感知面に当たることができるように配置されており、前記第2の光検知器の前記光感知面は、前記第2の通路内を進む光が前記第2の光検知器の光感知面に当たることができるように配置されている、前記第1及び第2の光検知器と、
少なくともその一部分が前記第1の穴内に配置されている第1の光学フィルタと、
少なくともその一部分が前記第2の穴内に配置されている第2の光学フィルタと、
前記第1の光学フィルタに対して直列に配置されている第3の光学フィルタと、
前記第2の光学フィルタに対して直列に配置されている第4の光学フィルタと、
前記第1の光検知器の光感知面に到達した光が前記第1及び第3の光学フィルタを通過し且つ前記第2の光検知器の光感知面に到達した光が前記第2及び第4の光学フィルタを通過するように、少なくとも前記第1及び第2の光学フィルタを覆っている黒色のエポキシ樹脂と、を含むセンサー。 - 請求項1に記載のセンサーであって、
前記回路基板がフェライトを含んでいるセンサー。 - 請求項1に記載のセンサーであって、
前記第1及び第2の光学フィルタがハイパスフィルタであるセンサー。 - 請求項1に記載のセンサーであって、
前記第3及び第4の光学フィルタが近赤外(NIR)フィルタであるセンサー。 - 請求項1に記載のセンサーであって、
前記回路基板の頂面に取り付けられた光源を更に含んでいるセンサー。 - 請求項1に記載のセンサーであって、
前記第1及び第2の光検知器の少なくとも1つの1以上の側面に光が当たるのを阻止するように配置された光遮断部材を更に含んでいるセンサー。 - 請求項6に記載のセンサーであって、
前記光遮断部材が黒色のエポキシ樹脂を含んでいるセンサー。 - 請求項1に記載のセンサーであって、
前記ハウジングの外面上に取り付けられた複数の指示分子を更に含んでいるセンサー。 - 請求項8に記載のセンサーであって、
前記指示分子が、前記ハウジングの外面上に配置されているポリマー基質層内に含まれているセンサー。 - 請求項9に記載のセンサーであって、
前記ポリマー基質層が高い多孔度を有しているセンサー。 - 請求項8に記載のセンサーであって、
前記指示分子を照射するために前記ハウジング内に収容されている光源を更に含んでいるセンサー。 - 請求項11に記載のセンサーであって、
前記光源が前記回路基板の頂面上に取り付けられているセンサー。 - 請求項11に記載のセンサーであって、
前記指示分子が蛍光状態にある間に、前記第1及び第2の光検知器のうちの一方の光感知面に当たる光の強度の関数である第1の信号出力を、前記第1及び第2の光検知器のうちの一方から取り込む手段と、
前記指示分子が照射されていない間に、前記第1及び第2の光検知器のうちの一方の光感知面に当たる光の強度の関数である第2の信号出力を、前記第1及び第2の光検知器のうちの一方から取り込む手段とを更に含んでいるセンサー。 - 請求項13に記載のセンサーであって、
前記第1及び第2の信号の関数である第3の信号を発生するための手段を更に含んでいるセンサー。 - 請求項14に記載のセンサーであって、
前記第3の信号を発生するための手段が前記第1の信号から前記第2の信号を差し引く手段を含んでいるセンサー。 - 請求項13に記載のセンサーであって、
前記第1の信号及び第2の信号をセンサー読み取り装置に送るためのトランスミッタを更に含んでいるセンサー。 - 請求項13に記載のセンサーであって、
約2ミリアンペアの電流によって光源を駆動することによって光源を作動させる手段を更に含んでいるセンサー。 - センサーであって、
ハウジングと、
前記ハウジング内に収容されたフェライト回路基板であって、該フェライト回路基板を貫通して形成されている第1及び第2の穴を備えており、該第1の穴は前記フェライト回路基板の頂面から前記フェライト回路基板の底面への第1の通路を形成しており、前記第2の穴は前記フェライト回路基板の頂面から該フェライト回路基板の底面への第2の通路を形成している前記フェライト回路基板と、
前記回路基板に取り付けられた第1及び第2の光検知器であって、各々、光感知面を有しており、前記第1の光検知器の前記光感知面は、前記第1の通路内を進む光が前記第1の光検知器の光感知面に当たることができるように配置されており、前記第2の光検知器の前記光感知面は、前記第2の通路内を進む光が前記第2の光検知器の光感知面に当たることができるように配置されている、前記第1及び第2の光検知器と、
少なくともその一部分が前記第1の穴内に配置されている第1の光学フィルタと、
少なくともその一部分が前記第2の穴内に配置されている第2の光学フィルタと、
前記第1の光学フィルタに対して直列に配置されている第1の近赤外(NIR)フィルタであって、前記第1の光検知器の光感知面に到達した光が前記第1のNIRフィルタ及び前記第1の光学フィルタを通過するようになされた前記第1の近赤外(NIR)フィルタと、
前記第2の光学フィルタに対して直列に配置されている第2の近赤外(NIR)フィルタであって、前記第2の光検知器の光感知面に到達した光が前記第2のNIRフィルタ及び前記第2の光学フィルタを通過するようになされた前記第2の近赤外(NIR)フィルタと、
前記ハウジング内に収容されている光源と、
前記ハウジング内に収容されているトランスミッタと、
前記ハウジングの外面上に配置されている複数の指示分子と、
前記第1及び第2の光検知器のうちの少なくとも1つの1以上の側面に光が当たるのを阻止するように配置されている光遮断材料と、を含んでおり、
前記光遮断材料が黒色のエポキシ樹脂を含んでいる、センサー。 - 請求項18に記載のセンサーであって、
前記第1及び第2の光学フィルタがハイパスフィルタであるセンサー。 - 請求項18に記載のセンサーであって、
前記光源が前記回路基板の頂面上に取り付けられているセンサー。 - 請求項18に記載のセンサーであって、
前記指示分子が、前記ハウジングの外面上に配置されているポリマー基質層内に含まれているセンサー。 - 請求項21に記載のセンサーであって、
前記ポリマー基質層が高い多孔度を有しているセンサー。 - 請求項18に記載のセンサーであって、
前記指示分子が蛍光状態にある間に、前記第1及び第2の光検知器のうちの一方の光感知面に当たる光の強度の関数である第1の信号出力を、前記第1及び第2の光検知器のうちの一方から取り込む手段と、
前記指示分子が照射されていない間に、前記第1及び第2の光検知器のうちの一方の光感知面に当たる光の強度の関数である第2の信号出力を、前記第1及び第2の光検知器のうちの一方から取り込む手段とを更に含んでいるセンサー。 - 請求項23に記載のセンサーであって、
前記第1及び第2の信号の関数である第3の信号を発生する手段を更に含んでいるセンサー。 - 請求項24に記載のセンサーであって、
前記第3の信号を発生する手段が、前記第1の信号から前記第2の信号を差し引く手段を含んでいるセンサー。 - 請求項23に記載のセンサーであって、
前記第1及び第2の信号をセンサー読み取り装置に送るためのトランスミッタを更に含んでいるセンサー。 - 請求項23に記載のセンサーであって、
約2ミリアンペアの電流によって光源を駆動することによって光源を作動させる手段を更に含んでいるセンサー。 - センサーであって、
ハウジングと、
前記ハウジング内に収容されている回路基板であって、該回路基板を貫通して形成されている第1及び第2の穴を備えており、該第1の穴は前記回路基板の頂面から前記回路基板の底面への第1の通路を形成しており、前記第2の穴は前記回路基板の頂面から前記回路基板の底面への第2の通路を形成しており、迷光が進入しない材料によって作られている前記回路基板と、
前記ハウジング内に収容され且つ前記回路基板の底面に取り付けられた第1及び第2の光検知器であって、各々、光感知面を有しており、前記第1の光検知器の前記光感知面は、前記第1の通路内を進む光が前記第1の光検知器の光感知面に当たることができるように配置されており、前記第2の光検知器の前記光感知面は、前記第2の通路内を進む光が前記第2の光検知器の光感知面に当たることができるように配置されている、前記第1及び第2の光検知器と、
少なくともその一部分が前記第1の穴内に配置されている第1の光学フィルタと、
少なくともその一部分が前記第2の穴内に配置されている第2の光学フィルタと、
前記第1の光学フィルタに対して直列に配置されている第3の光学フィルタと、
前記第2の光学フィルタに対して直列に配置されている第4の光学フィルタと、
前記ハウジング内に収容され且つ前記回路基板の頂面に取り付けられている少なくとも1つの光源と、
前記ハウジング内に収容されているトランスミッタと、
前記ハウジングの外面上に配置されている高い多孔度を有するポリマー基質層内に含まれている複数の指示分子であって、該ポリマー基質層内の指示分子は、前記光源から射出された光を受け取って蛍光を発し、前記第1の光検知器の光感知面が、前記第3の光学フィルタ及び前記第1の光学フィルタを通過した後に前記指示分子によって発せられる蛍光を受け取るようになされている、前記複数の指示分子と、
光が前記第1及び第2の光検知器のうちの少なくとも1つにおける1以上の側面に当たるのを阻止するように配置された光遮断材料と、を含んでおり、
前記光遮断材料が黒色のエポキシ樹脂を含んでいる、センサー。 - 請求項28に記載のセンサーであって、
前記回路基板がフェライト回路基板であるセンサー。 - 請求項28に記載のセンサーであって、
前記第1及び第2の光学フィルタがハイパスフィルタであるセンサー。 - 請求項28に記載のセンサーであって、
前記第3及び第4の光学フィルタが近赤外(NIR)フィルタであるセンサー。 - 請求項28に記載のセンサーであって、
前記指示分子が蛍光状態にある間に、前記第1及び第2の光検知器のうちの一方の光感知面に当たる光の強度の関数である第1の信号出力を、前記第1及び第2の光検知器のうちの一方から取り込む手段と、
前記指示分子が照射されていない間に、前記第1及び第2の光検知器のうちの一方の光感知面に当たる光の強度の関数である第2の信号出力を、前記第1及び第2の光検知器のうちの一方から取り込む手段とを更に含んでいるセンサー。 - 請求項32に記載のセンサーであって、
前記第1及び第2の信号の関数である第3の信号を発生するための手段を更に含んでいるセンサー。 - 請求項32に記載のセンサーであって、
前記第3の信号を発生するための手段が、前記第1の信号から前記第2の信号を差し引く手段を含んでいるセンサー。 - 請求項32に記載のセンサーであって、
前記第1及び第2の信号をセンサー読み取り装置に送るためのトランスミッタを更に含んでいるセンサー。 - 請求項32に記載のセンサーであって、
約2ミリアンペアの電流によって光源を駆動することによって光源を作動させるための手段を更に含んでいるセンサー。
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