CN1531426A - 有机化合物 - Google Patents

有机化合物 Download PDF

Info

Publication number
CN1531426A
CN1531426A CNA018210155A CN01821015A CN1531426A CN 1531426 A CN1531426 A CN 1531426A CN A018210155 A CNA018210155 A CN A018210155A CN 01821015 A CN01821015 A CN 01821015A CN 1531426 A CN1531426 A CN 1531426A
Authority
CN
China
Prior art keywords
halogenated
alkyl
general formula
monosubstituted
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA018210155A
Other languages
English (en)
Chinese (zh)
Inventor
P
P·迪克雷
�Ү��
J·布维耶
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1531426A publication Critical patent/CN1531426A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paper (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNA018210155A 2000-12-20 2001-12-18 有机化合物 Pending CN1531426A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH2489/2000 2000-12-20
CH24892000 2000-12-20

Publications (1)

Publication Number Publication Date
CN1531426A true CN1531426A (zh) 2004-09-22

Family

ID=4569596

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA018210155A Pending CN1531426A (zh) 2000-12-20 2001-12-18 有机化合物

Country Status (21)

Country Link
US (1) US7700656B2 (cg-RX-API-DMAC7.html)
EP (1) EP1392281B1 (cg-RX-API-DMAC7.html)
JP (1) JP2004521097A (cg-RX-API-DMAC7.html)
KR (1) KR100850252B1 (cg-RX-API-DMAC7.html)
CN (1) CN1531426A (cg-RX-API-DMAC7.html)
AR (1) AR035523A1 (cg-RX-API-DMAC7.html)
AT (1) ATE354360T1 (cg-RX-API-DMAC7.html)
AU (2) AU2002234588B2 (cg-RX-API-DMAC7.html)
BR (1) BR0116326A (cg-RX-API-DMAC7.html)
CA (1) CA2432388C (cg-RX-API-DMAC7.html)
CY (1) CY1106509T1 (cg-RX-API-DMAC7.html)
DE (1) DE60126838T2 (cg-RX-API-DMAC7.html)
DK (1) DK1392281T3 (cg-RX-API-DMAC7.html)
ES (1) ES2281453T3 (cg-RX-API-DMAC7.html)
MX (1) MXPA03005701A (cg-RX-API-DMAC7.html)
NZ (1) NZ526538A (cg-RX-API-DMAC7.html)
PT (1) PT1392281E (cg-RX-API-DMAC7.html)
RU (1) RU2286775C2 (cg-RX-API-DMAC7.html)
TW (1) TWI292712B (cg-RX-API-DMAC7.html)
WO (1) WO2002049641A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200304331B (cg-RX-API-DMAC7.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102821604A (zh) * 2010-03-25 2012-12-12 诺瓦提斯公司 杀内寄生虫的组合物
CN104105688A (zh) * 2012-02-14 2014-10-15 日本曹达株式会社 芳氧基乙酰胺化合物和有害生物防除剂
CN104203223A (zh) * 2011-11-25 2014-12-10 拜耳知识产权有限责任公司 芳基甲酰胺和杂芳基甲酰胺作为杀体内寄生虫剂的用途

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
AR036054A1 (es) 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) * 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
AR037746A1 (es) 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
TW200305556A (en) * 2002-03-21 2003-11-01 Novartis Ag Organic compounds
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
TW200409760A (en) * 2002-09-11 2004-06-16 Novartis Ag Organic compounds
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
AR049391A1 (es) * 2004-06-10 2006-07-26 Novartis Ag Derivados de aminoacetonitrilo y su uso para controlar parasitos en animales de sangre caliente
WO2006043654A1 (ja) * 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
US7485751B2 (en) * 2004-11-09 2009-02-03 Novartis Animal Health Us, Inc. Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
US20080227863A1 (en) * 2005-07-25 2008-09-18 Novartis Ag Organic Compounds
DE102006025874A1 (de) 2006-06-02 2007-12-06 Bayer Cropscience Ag Alkoxyalkyl-substituierte cyclische Ketoenole
WO2008062005A1 (en) * 2006-11-24 2008-05-29 Novartis Ag The use of aminoacetonitril compounds in the control of endoparasites in warm- blood animals.
MX2009007482A (es) 2007-02-09 2009-08-13 Pfizer Ltd Agentes antiparasitarios.
AU2008217028B2 (en) * 2007-02-21 2013-07-25 Zoetis Uk Limited Benzofuran antiparasitic agents
PT2155699E (pt) * 2007-05-15 2015-11-12 Merial Inc Compostos de ariloazol-2-il-cianoetilamino, método de fabrico e método de utilização
CA2741186C (en) 2008-10-21 2016-07-19 Merial Limited Thioamide compounds, method of making and method of using thereof
CA2945453C (en) 2008-11-14 2021-03-02 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino paraciticidal compounds
BR112013021337B1 (pt) * 2011-03-02 2019-09-03 Nihon Nohyaku Co Ltd composição compreendendo um derivado de carboxamida para uso no controle de endoparasitas
PL2880014T3 (pl) * 2012-08-06 2017-10-31 Pitney Pharmaceuticals Pty Ltd Związki do leczenia chorób związanych ze szlakiem mTOR
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
EP2821412A1 (en) * 2013-07-01 2015-01-07 Universität Zürich Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics
US9907778B2 (en) * 2013-09-13 2018-03-06 Pitney Pharmaceuticals Pty Limited Anticancer agent comprising aminoacetonitrile compound as active ingredient
EP3261636A1 (en) * 2015-02-24 2018-01-03 Pitney Pharmaceuticals Pty Limited Anti cancer agent comprising aminoacetonitrile compound as active ingredient
EP3235815A1 (de) 2016-04-19 2017-10-25 Philipps-Universität Marburg Wirkstoffe gegen parasitäre helminthen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3457294A (en) * 1966-04-22 1969-07-22 Abbott Lab N-(substituted-benzoyl) aminoaceto- and aminopropionitriles
FR1520925A (fr) * 1966-04-22 1968-04-12 Abbott Lab Nouveaux benzoylamino-nitriles
US4515731A (en) * 1975-08-25 1985-05-07 Monsanto Company Asymmetric catalysis
GB8517279D0 (en) * 1985-07-08 1985-08-14 Ici Plc Benzamide derivatives
JP2994182B2 (ja) * 1992-07-23 1999-12-27 石原産業株式会社 アミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
RU2284990C2 (ru) * 2001-05-15 2006-10-10 Новартис Аг Производные бензамидоацетонитрила, способ их получения, содержащая их композиция для борьбы с нематодами и их применение
AR036054A1 (es) * 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
AR038156A1 (es) * 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102821604A (zh) * 2010-03-25 2012-12-12 诺瓦提斯公司 杀内寄生虫的组合物
CN102821604B (zh) * 2010-03-25 2014-09-10 诺华股份有限公司 杀内寄生虫的组合物
CN104203223A (zh) * 2011-11-25 2014-12-10 拜耳知识产权有限责任公司 芳基甲酰胺和杂芳基甲酰胺作为杀体内寄生虫剂的用途
CN104105688A (zh) * 2012-02-14 2014-10-15 日本曹达株式会社 芳氧基乙酰胺化合物和有害生物防除剂

Also Published As

Publication number Publication date
DE60126838D1 (de) 2007-04-05
CA2432388C (en) 2010-06-08
ATE354360T1 (de) 2007-03-15
EP1392281B1 (en) 2007-02-21
KR20030061414A (ko) 2003-07-18
US20040082624A1 (en) 2004-04-29
AU3458802A (en) 2002-07-01
AR035523A1 (es) 2004-06-02
WO2002049641A2 (en) 2002-06-27
TWI292712B (en) 2008-01-21
DE60126838T2 (de) 2007-11-08
NZ526538A (en) 2005-12-23
AU2002234588B2 (en) 2005-03-24
WO2002049641A3 (en) 2003-12-04
RU2286775C2 (ru) 2006-11-10
PT1392281E (pt) 2007-05-31
EP1392281A2 (en) 2004-03-03
ES2281453T3 (es) 2007-10-01
MXPA03005701A (es) 2003-10-06
KR100850252B1 (ko) 2008-08-04
ZA200304331B (en) 2004-04-28
DK1392281T3 (da) 2007-06-11
BR0116326A (pt) 2004-07-06
US7700656B2 (en) 2010-04-20
CY1106509T1 (el) 2012-01-25
CA2432388A1 (en) 2002-06-27
JP2004521097A (ja) 2004-07-15
RU2003122196A (ru) 2005-03-20

Similar Documents

Publication Publication Date Title
CN1531426A (zh) 有机化合物
CN1196700C (zh) 作为杀虫剂和抗寄生物药剂的氨基杂环基酰胺
CN1177823C (zh) 杀虫剂
CN1692104A (zh) 苯并三唑－1－基－氨基乙腈化合物及其在控制寄生虫疾病中的应用
CN1487788A (zh) 含有氨基乙腈化合物的药物组合物和该化合物在制备用于治疗动物中的体内寄生虫的药物组合物中的用途
CN1304378C (zh) 用于控制寄生虫的苯并咪唑－或吲哚－氨基乙腈衍生物
CN1564809A (zh) 有机化合物
CN1902162A (zh) 酰氨基乙腈衍生物
CN1384832A (zh) 作为农药的氨基杂环基酰胺化合物
CN1293047C (zh) 适用于控制寄生虫的氨基乙腈衍生物
CN1384826A (zh) 作为农药的N－杂芳基－α－烷氧亚氨基羧酸酰胺
CN1545504A (zh) 具有特殊杀虫活性的吲唑-氨基乙腈衍生物
CN1529552A (zh) 用于防治体内寄生虫的氨基乙腈化合物
CN1309715C (zh) N－酰氨基乙腈衍生物及其用于制备控制寄生虫的药物中的用途
AU2002250841A1 (en) Pharmaceutical composition containing aminoacetonitril compounds and the use thereof for the prepartion of a pharmaceutical composition for the treatment of endoparasitic pests in animals
CN1890209A (zh) 酰氨基乙腈衍生物
CN1656061A (zh) 有机化合物
CN100347153C (zh) 酰氨基乙腈化合物及其作为杀虫剂的用途
CN1602296A (zh) 氨基乙腈衍生物
CN1930134A (zh) 嘧啶化合物在制备杀寄生物药中的用途
CN1241907C (zh) 有机化合物
CN1545500A (zh) 作为抗寄生虫剂的羰氧基-氰基甲基化合物
CN1135225C (zh) 对映异构体纯的2,4－二取代噁唑啉的制备和应用

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication