CA2432388C - Aminoacetonitriles to control endoparasitic pests - Google Patents

Aminoacetonitriles to control endoparasitic pests Download PDF

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Publication number
CA2432388C
CA2432388C CA2432388A CA2432388A CA2432388C CA 2432388 C CA2432388 C CA 2432388C CA 2432388 A CA2432388 A CA 2432388A CA 2432388 A CA2432388 A CA 2432388A CA 2432388 C CA2432388 C CA 2432388C
Authority
CA
Canada
Prior art keywords
halogen
alkyl
substituted
hydrogen
signifies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2432388A
Other languages
English (en)
French (fr)
Other versions
CA2432388A1 (en
Inventor
Pierre Ducray
Jacques Bouvier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elanco Tiergesundheit AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2432388A1 publication Critical patent/CA2432388A1/en
Application granted granted Critical
Publication of CA2432388C publication Critical patent/CA2432388C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paper (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA2432388A 2000-12-20 2001-12-18 Aminoacetonitriles to control endoparasitic pests Expired - Lifetime CA2432388C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH24892000 2000-12-20
CH2489/00 2000-12-20
PCT/EP2001/014926 WO2002049641A2 (en) 2000-12-20 2001-12-18 Anti-endoparasitic amidoacetonitrils

Publications (2)

Publication Number Publication Date
CA2432388A1 CA2432388A1 (en) 2002-06-27
CA2432388C true CA2432388C (en) 2010-06-08

Family

ID=4569596

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2432388A Expired - Lifetime CA2432388C (en) 2000-12-20 2001-12-18 Aminoacetonitriles to control endoparasitic pests

Country Status (21)

Country Link
US (1) US7700656B2 (cg-RX-API-DMAC7.html)
EP (1) EP1392281B1 (cg-RX-API-DMAC7.html)
JP (1) JP2004521097A (cg-RX-API-DMAC7.html)
KR (1) KR100850252B1 (cg-RX-API-DMAC7.html)
CN (1) CN1531426A (cg-RX-API-DMAC7.html)
AR (1) AR035523A1 (cg-RX-API-DMAC7.html)
AT (1) ATE354360T1 (cg-RX-API-DMAC7.html)
AU (2) AU2002234588B2 (cg-RX-API-DMAC7.html)
BR (1) BR0116326A (cg-RX-API-DMAC7.html)
CA (1) CA2432388C (cg-RX-API-DMAC7.html)
CY (1) CY1106509T1 (cg-RX-API-DMAC7.html)
DE (1) DE60126838T2 (cg-RX-API-DMAC7.html)
DK (1) DK1392281T3 (cg-RX-API-DMAC7.html)
ES (1) ES2281453T3 (cg-RX-API-DMAC7.html)
MX (1) MXPA03005701A (cg-RX-API-DMAC7.html)
NZ (1) NZ526538A (cg-RX-API-DMAC7.html)
PT (1) PT1392281E (cg-RX-API-DMAC7.html)
RU (1) RU2286775C2 (cg-RX-API-DMAC7.html)
TW (1) TWI292712B (cg-RX-API-DMAC7.html)
WO (1) WO2002049641A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200304331B (cg-RX-API-DMAC7.html)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
AR036054A1 (es) 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) * 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
AR037746A1 (es) 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
TW200305556A (en) * 2002-03-21 2003-11-01 Novartis Ag Organic compounds
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
TW200409760A (en) * 2002-09-11 2004-06-16 Novartis Ag Organic compounds
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
AR049391A1 (es) * 2004-06-10 2006-07-26 Novartis Ag Derivados de aminoacetonitrilo y su uso para controlar parasitos en animales de sangre caliente
WO2006043654A1 (ja) * 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
US7485751B2 (en) * 2004-11-09 2009-02-03 Novartis Animal Health Us, Inc. Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates
US20080227863A1 (en) * 2005-07-25 2008-09-18 Novartis Ag Organic Compounds
DE102006025874A1 (de) 2006-06-02 2007-12-06 Bayer Cropscience Ag Alkoxyalkyl-substituierte cyclische Ketoenole
WO2008062005A1 (en) * 2006-11-24 2008-05-29 Novartis Ag The use of aminoacetonitril compounds in the control of endoparasites in warm- blood animals.
MX2009007482A (es) 2007-02-09 2009-08-13 Pfizer Ltd Agentes antiparasitarios.
AU2008217028B2 (en) * 2007-02-21 2013-07-25 Zoetis Uk Limited Benzofuran antiparasitic agents
PT2155699E (pt) * 2007-05-15 2015-11-12 Merial Inc Compostos de ariloazol-2-il-cianoetilamino, método de fabrico e método de utilização
CA2741186C (en) 2008-10-21 2016-07-19 Merial Limited Thioamide compounds, method of making and method of using thereof
CA2945453C (en) 2008-11-14 2021-03-02 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino paraciticidal compounds
UY33282A (es) * 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
BR112013021337B1 (pt) * 2011-03-02 2019-09-03 Nihon Nohyaku Co Ltd composição compreendendo um derivado de carboxamida para uso no controle de endoparasitas
SI2782565T1 (sl) * 2011-11-25 2019-12-31 Bayer Intellectual Property Gmbh Uporaba aril in hetaril karboksamidov kot endoparaziticid
BR112014018875A8 (pt) * 2012-02-14 2017-07-11 Nippon Soda Co Composto de ariloxiacetamida ou sal do mesmo, pesticida, acaricida ou inseticida, e, agente de controle de ectoparasita
PL2880014T3 (pl) * 2012-08-06 2017-10-31 Pitney Pharmaceuticals Pty Ltd Związki do leczenia chorób związanych ze szlakiem mTOR
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
EP2821412A1 (en) * 2013-07-01 2015-01-07 Universität Zürich Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics
US9907778B2 (en) * 2013-09-13 2018-03-06 Pitney Pharmaceuticals Pty Limited Anticancer agent comprising aminoacetonitrile compound as active ingredient
EP3261636A1 (en) * 2015-02-24 2018-01-03 Pitney Pharmaceuticals Pty Limited Anti cancer agent comprising aminoacetonitrile compound as active ingredient
EP3235815A1 (de) 2016-04-19 2017-10-25 Philipps-Universität Marburg Wirkstoffe gegen parasitäre helminthen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3457294A (en) * 1966-04-22 1969-07-22 Abbott Lab N-(substituted-benzoyl) aminoaceto- and aminopropionitriles
FR1520925A (fr) * 1966-04-22 1968-04-12 Abbott Lab Nouveaux benzoylamino-nitriles
US4515731A (en) * 1975-08-25 1985-05-07 Monsanto Company Asymmetric catalysis
GB8517279D0 (en) * 1985-07-08 1985-08-14 Ici Plc Benzamide derivatives
JP2994182B2 (ja) * 1992-07-23 1999-12-27 石原産業株式会社 アミド系化合物又はその塩、それらの製造方法及びそれらを含有する有害動物防除剤
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
RU2284990C2 (ru) * 2001-05-15 2006-10-10 Новартис Аг Производные бензамидоацетонитрила, способ их получения, содержащая их композиция для борьбы с нематодами и их применение
AR036054A1 (es) * 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
AR038156A1 (es) * 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica

Also Published As

Publication number Publication date
DE60126838D1 (de) 2007-04-05
ATE354360T1 (de) 2007-03-15
EP1392281B1 (en) 2007-02-21
KR20030061414A (ko) 2003-07-18
US20040082624A1 (en) 2004-04-29
AU3458802A (en) 2002-07-01
AR035523A1 (es) 2004-06-02
WO2002049641A2 (en) 2002-06-27
TWI292712B (en) 2008-01-21
DE60126838T2 (de) 2007-11-08
CN1531426A (zh) 2004-09-22
NZ526538A (en) 2005-12-23
AU2002234588B2 (en) 2005-03-24
WO2002049641A3 (en) 2003-12-04
RU2286775C2 (ru) 2006-11-10
PT1392281E (pt) 2007-05-31
EP1392281A2 (en) 2004-03-03
ES2281453T3 (es) 2007-10-01
MXPA03005701A (es) 2003-10-06
KR100850252B1 (ko) 2008-08-04
ZA200304331B (en) 2004-04-28
DK1392281T3 (da) 2007-06-11
BR0116326A (pt) 2004-07-06
US7700656B2 (en) 2010-04-20
CY1106509T1 (el) 2012-01-25
CA2432388A1 (en) 2002-06-27
JP2004521097A (ja) 2004-07-15
RU2003122196A (ru) 2005-03-20

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Effective date: 20211220