CN1303155C - 具有改进稳定性的聚合物胶束组合物 - Google Patents

具有改进稳定性的聚合物胶束组合物 Download PDF

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Publication number
CN1303155C
CN1303155C CNB028205731A CN02820573A CN1303155C CN 1303155 C CN1303155 C CN 1303155C CN B028205731 A CNB028205731 A CN B028205731A CN 02820573 A CN02820573 A CN 02820573A CN 1303155 C CN1303155 C CN 1303155C
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polymer
pla
aqueous solution
polylactic acid
block
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Chinese (zh)
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CN1571816A (zh
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徐敏孝
李思元
金希祚
金廷景
玄明韩
刘正一
金峯五
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Sanyang Holding Co
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Samyang Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L53/005—Modified block copolymers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polyesters Or Polycarbonates (AREA)
CNB028205731A 2001-10-18 2002-10-17 具有改进稳定性的聚合物胶束组合物 Expired - Lifetime CN1303155C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20010064468 2001-10-18
KR2001/64468 2001-10-18
KR20010076213 2001-12-04
KR2001/76213 2001-12-04

Publications (2)

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CN1571816A CN1571816A (zh) 2005-01-26
CN1303155C true CN1303155C (zh) 2007-03-07

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US (1) US7879317B2 (enExample)
EP (1) EP1448707B1 (enExample)
JP (1) JP3955846B2 (enExample)
CN (1) CN1303155C (enExample)
AT (1) ATE370988T1 (enExample)
AU (1) AU2002348660B2 (enExample)
CA (1) CA2463172C (enExample)
DE (1) DE60222007T2 (enExample)
ES (1) ES2292827T3 (enExample)
MX (1) MXPA04003621A (enExample)
NZ (1) NZ532198A (enExample)
WO (1) WO2003033592A1 (enExample)

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JP2006199590A (ja) * 2003-09-04 2006-08-03 Nano Career Kk 水溶性の塩基性薬物内包ナノ粒子含有組成物
ITMI20031872A1 (it) * 2003-09-30 2005-04-01 Mediolanum Farmaceutici Srl Copolimeri di poliesteri e polivinilpirrolidone.
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US8853351B2 (en) 2007-12-31 2014-10-07 Samyang Biopharmaceuticals Corporation Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof
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CN103479573B (zh) * 2013-07-26 2017-04-19 中国科学院长春应用化学研究所 聚乙二醇单甲醚‑聚酯两嵌段共聚物胶束及载药胶束的制备方法
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KR101745429B1 (ko) 2015-07-28 2017-06-12 주식회사 삼양바이오팜 양친성 블록 공중합체의 정제방법, 이로부터 얻어지는 양친성 블록 공중합체, 및 이를 포함하는 약학 조성물
KR101748191B1 (ko) * 2015-07-28 2017-06-19 주식회사 삼양바이오팜 보관 안정성이 향상된 약학 조성물 및 그의 제조 방법
KR101787447B1 (ko) * 2015-07-28 2017-10-19 주식회사 삼양바이오팜 보관 안정성이 향상된 약학 조성물 및 그의 제조 방법
KR101787451B1 (ko) * 2015-07-28 2017-10-19 주식회사 삼양바이오팜 보관 안정성이 향상된 약학 조성물 및 그의 제조 방법
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Also Published As

Publication number Publication date
ES2292827T3 (es) 2008-03-16
DE60222007D1 (de) 2007-10-04
US7879317B2 (en) 2011-02-01
AU2002348660B2 (en) 2006-01-12
WO2003033592A1 (en) 2003-04-24
CA2463172C (en) 2009-08-18
EP1448707A1 (en) 2004-08-25
JP2005505674A (ja) 2005-02-24
CN1571816A (zh) 2005-01-26
MXPA04003621A (es) 2004-07-30
CA2463172A1 (en) 2003-04-24
DE60222007T2 (de) 2008-05-15
EP1448707B1 (en) 2007-08-22
JP3955846B2 (ja) 2007-08-08
NZ532198A (en) 2006-03-31
ATE370988T1 (de) 2007-09-15
US20040253195A1 (en) 2004-12-16

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