CN1252065A - 取代的噻唑烷二酮的制备方法 - Google Patents
取代的噻唑烷二酮的制备方法 Download PDFInfo
- Publication number
- CN1252065A CN1252065A CN98804121A CN98804121A CN1252065A CN 1252065 A CN1252065 A CN 1252065A CN 98804121 A CN98804121 A CN 98804121A CN 98804121 A CN98804121 A CN 98804121A CN 1252065 A CN1252065 A CN 1252065A
- Authority
- CN
- China
- Prior art keywords
- compound
- formula
- borohydride
- solvate
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9703310.4A GB9703310D0 (en) | 1997-02-18 | 1997-02-18 | Novel process |
| GBGB9703334.4A GB9703334D0 (en) | 1997-02-18 | 1997-02-18 | Novel compounds |
| GB9703338.5 | 1997-02-18 | ||
| GBGB9703338.5A GB9703338D0 (en) | 1997-02-18 | 1997-02-18 | Novel process |
| GB9703310.4 | 1997-02-18 | ||
| GB9703334.4 | 1997-02-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1252065A true CN1252065A (zh) | 2000-05-03 |
Family
ID=27268725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98804121A Pending CN1252065A (zh) | 1997-02-18 | 1998-02-13 | 取代的噻唑烷二酮的制备方法 |
Country Status (29)
| Country | Link |
|---|---|
| EP (2) | EP0970063A1 (enExample) |
| JP (2) | JP2001514619A (enExample) |
| KR (1) | KR20000071138A (enExample) |
| CN (1) | CN1252065A (enExample) |
| AP (1) | AP1359A (enExample) |
| AR (1) | AR011447A1 (enExample) |
| AU (1) | AU6622398A (enExample) |
| BG (1) | BG64311B1 (enExample) |
| BR (1) | BR9807395A (enExample) |
| CA (1) | CA2281695C (enExample) |
| CZ (1) | CZ296272B6 (enExample) |
| DZ (1) | DZ2430A1 (enExample) |
| EA (1) | EA199900754A1 (enExample) |
| HU (1) | HUP0001459A3 (enExample) |
| ID (1) | ID22222A (enExample) |
| IL (1) | IL131392A (enExample) |
| IN (1) | IN188379B (enExample) |
| MA (1) | MA24475A1 (enExample) |
| MY (1) | MY129475A (enExample) |
| NO (2) | NO313290B1 (enExample) |
| NZ (1) | NZ337179A (enExample) |
| OA (1) | OA11148A (enExample) |
| PE (1) | PE71899A1 (enExample) |
| PL (1) | PL195482B1 (enExample) |
| SK (2) | SK285979B6 (enExample) |
| TR (1) | TR199902019T2 (enExample) |
| TW (1) | TWI222446B (enExample) |
| UY (1) | UY24886A1 (enExample) |
| WO (1) | WO1998037073A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9723295D0 (en) | 1997-11-04 | 1998-01-07 | Smithkline Beecham Plc | Novel process |
| US7091359B2 (en) | 1997-11-04 | 2006-08-15 | Smithkline Beecham Plc | Process for the preparation of thiazolidinedione derivatives |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| DK1173435T3 (da) * | 1999-04-23 | 2003-11-24 | Smithkline Beecham Cork Ltd | Polymorf af 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxyl]benzyl]thiazolidin-2,4-dion, maleinsyresalt |
| FR2820742B1 (fr) * | 2001-02-14 | 2005-03-11 | Ppg Sipsy | Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine |
| FR2820741A1 (fr) * | 2001-02-14 | 2002-08-16 | Ppg Sipsy | Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine |
| SI1567112T1 (sl) | 2002-11-22 | 2009-02-28 | Smithkline Beecham Corp | Thiazolidin-4-oni za inhibiranje proteinov hyak3 |
| AR047541A1 (es) * | 2004-02-13 | 2006-01-25 | Sandoz Ag | Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas |
| CA2566352A1 (en) * | 2004-05-12 | 2005-11-17 | Medichem S.A. | Process for the preparation of rosiglitazone |
| CZ297266B6 (cs) * | 2004-09-10 | 2006-10-11 | Zentiva, A. S. | Zpusob prípravy rosiglitazonu |
| CZ297347B6 (cs) * | 2004-09-21 | 2006-11-15 | Zentiva, A. S. | Zpusob prípravy rosiglitazonu |
| CZ298424B6 (cs) * | 2005-05-24 | 2007-09-26 | Zentiva, A. S. | Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| SG59988A1 (en) * | 1987-09-04 | 1999-02-22 | Beecham Group Plc | Substituted thiazolidinedione derivatives |
| JPH0377875A (ja) * | 1989-08-18 | 1991-04-03 | Kaken Pharmaceut Co Ltd | チアゾリジン‐２，４‐ジオン誘導体およびその製造法 |
| DE69132713D1 (de) * | 1990-04-27 | 2001-10-11 | Sankyo Co | Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren |
| AU3231093A (en) * | 1991-12-20 | 1993-07-28 | Upjohn Company, The | A reduction method for substituted 5-methylene-thiazolidinediones |
| JPH08157473A (ja) * | 1994-10-06 | 1996-06-18 | Nissan Chem Ind Ltd | ピラゾール系チアゾリジン類 |
| JPH08217717A (ja) * | 1995-02-10 | 1996-08-27 | Sumitomo Chem Co Ltd | 環状ケトン系化合物、その製造法およびそれを有効成分とするゴキブリ誘引剤 |
| ATE272635T1 (de) * | 1995-05-31 | 2004-08-15 | Sumitomo Pharma | Neue naphthyridinderivate. |
-
1998
- 1998-02-11 UY UY24886A patent/UY24886A1/es not_active Application Discontinuation
- 1998-02-13 WO PCT/EP1998/000818 patent/WO1998037073A1/en not_active Ceased
- 1998-02-13 CA CA002281695A patent/CA2281695C/en not_active Expired - Fee Related
- 1998-02-13 ID IDW990876A patent/ID22222A/id unknown
- 1998-02-13 CN CN98804121A patent/CN1252065A/zh active Pending
- 1998-02-13 IL IL13139298A patent/IL131392A/xx unknown
- 1998-02-13 BR BR9807395-8A patent/BR9807395A/pt not_active Application Discontinuation
- 1998-02-13 EP EP98908093A patent/EP0970063A1/en not_active Withdrawn
- 1998-02-13 PL PL98335163A patent/PL195482B1/pl not_active IP Right Cessation
- 1998-02-13 JP JP53622998A patent/JP2001514619A/ja not_active Withdrawn
- 1998-02-13 AP APAP/P/1999/001626A patent/AP1359A/en active
- 1998-02-13 TR TR1999/02019T patent/TR199902019T2/xx unknown
- 1998-02-13 NZ NZ337179A patent/NZ337179A/en not_active IP Right Cessation
- 1998-02-13 AU AU66223/98A patent/AU6622398A/en not_active Abandoned
- 1998-02-13 EA EA199900754A patent/EA199900754A1/ru unknown
- 1998-02-13 SK SK1120-99A patent/SK285979B6/sk not_active IP Right Cessation
- 1998-02-13 SK SK63-2007A patent/SK287512B6/sk not_active IP Right Cessation
- 1998-02-13 KR KR1019997007427A patent/KR20000071138A/ko not_active Withdrawn
- 1998-02-13 HU HU0001459A patent/HUP0001459A3/hu unknown
- 1998-02-13 CZ CZ0292499A patent/CZ296272B6/cs not_active IP Right Cessation
- 1998-02-13 EP EP06002536A patent/EP1770092A1/en not_active Withdrawn
- 1998-02-14 MY MYPI98000629A patent/MY129475A/en unknown
- 1998-02-16 PE PE1998000107A patent/PE71899A1/es not_active Application Discontinuation
- 1998-02-16 MA MA24966A patent/MA24475A1/fr unknown
- 1998-02-16 AR ARP980100684A patent/AR011447A1/es active IP Right Grant
- 1998-02-17 DZ DZ980040A patent/DZ2430A1/xx active
- 1998-02-18 IN IN417DE1998 patent/IN188379B/en unknown
- 1998-03-11 TW TW087103522A patent/TWI222446B/zh active
-
1999
- 1999-08-17 NO NO19993949A patent/NO313290B1/no not_active IP Right Cessation
- 1999-08-18 OA OA9900183A patent/OA11148A/en unknown
- 1999-09-15 BG BG103735A patent/BG64311B1/bg unknown
-
2002
- 2002-08-19 NO NO20023937A patent/NO20023937D0/no not_active Application Discontinuation
-
2008
- 2008-11-20 JP JP2008296785A patent/JP2009149616A/ja active Pending
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |