CN115089569A - 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途 - Google Patents

双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途 Download PDF

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CN115089569A
CN115089569A CN202210355615.0A CN202210355615A CN115089569A CN 115089569 A CN115089569 A CN 115089569A CN 202210355615 A CN202210355615 A CN 202210355615A CN 115089569 A CN115089569 A CN 115089569A
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cancer
chemotherapy
tsc
administering
bipolar trans
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约翰·L·盖纳
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Diffusion Pharmaceuticals LLC
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Diffusion Pharmaceuticals LLC
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4164—1,3-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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  • Radiology & Medical Imaging (AREA)
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202210355615.0A 2016-03-24 2017-03-23 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途 Pending CN115089569A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662312988P 2016-03-24 2016-03-24
US62/312,988 2016-03-24
CN201780010816.4A CN109152839A (zh) 2016-03-24 2017-03-23 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途
PCT/US2017/023844 WO2017165667A1 (en) 2016-03-24 2017-03-23 Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer

Related Parent Applications (1)

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CN201780010816.4A Division CN109152839A (zh) 2016-03-24 2017-03-23 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途

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CN115089569A true CN115089569A (zh) 2022-09-23

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CN201780010816.4A Pending CN109152839A (zh) 2016-03-24 2017-03-23 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途
CN202210355615.0A Pending CN115089569A (zh) 2016-03-24 2017-03-23 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途

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US (2) US11185523B2 (enExample)
EP (1) EP3432929A4 (enExample)
JP (2) JP7032320B2 (enExample)
KR (2) KR102489034B1 (enExample)
CN (2) CN109152839A (enExample)
CA (1) CA3018550A1 (enExample)
IL (1) IL261922A (enExample)
WO (1) WO2017165667A1 (enExample)

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EA017982B1 (ru) 2005-02-24 2013-04-30 ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли
EP3539542B1 (en) 2009-06-22 2023-04-19 Diffusion Pharmaceuticals LLC Diffusion enhancing compounds and their use with a thrombolytic
ES2654945T3 (es) 2010-06-02 2018-02-15 Diffusion Pharmaceuticals Llc Formulaciones orales de carotenoides trans bipolares
EP3432929A4 (en) 2016-03-24 2019-11-27 Diffusion Pharmaceuticals LLC USE OF BIPOLAR TRANSCAROTINOIDS WITH CHEMOTHERAPY AND RADIOTHERAPY FOR THE TREATMENT OF CANCER
CA3098868A1 (en) * 2018-05-03 2019-11-07 L.E.A.F. Holdings Group Llc Carotenoid compositions and uses thereof
WO2022025998A1 (en) * 2020-07-27 2022-02-03 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
WO2022150716A1 (en) * 2021-01-10 2022-07-14 Diffusion Pharmaceuticals Llc Methods of treating wounds and burns
US20250064768A1 (en) * 2021-05-10 2025-02-27 L.E.A.F. Holdings Group Llc Methods and compositions for treating aging and chronic disease
WO2023279033A1 (en) * 2021-06-29 2023-01-05 Diffusion Pharmaceuticals Llc Methods of treatment

Citations (3)

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US20080255246A1 (en) * 2007-04-13 2008-10-16 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
CN104840455A (zh) * 2005-02-24 2015-08-19 扩散药品有限公司 反式类胡萝卜素、其合成、制剂和用途
CN105287473A (zh) * 2010-06-02 2016-02-03 扩散药品有限公司 包含双极性反式类胡萝卜素的组合物及其应用

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