ITMI20052486A1 - Procedimento di sintesi di intermedi per la preparazione di astaxantina - Google Patents

Procedimento di sintesi di intermedi per la preparazione di astaxantina

Info

Publication number
ITMI20052486A1
ITMI20052486A1 IT002486A ITMI20052486A ITMI20052486A1 IT MI20052486 A1 ITMI20052486 A1 IT MI20052486A1 IT 002486 A IT002486 A IT 002486A IT MI20052486 A ITMI20052486 A IT MI20052486A IT MI20052486 A1 ITMI20052486 A1 IT MI20052486A1
Authority
IT
Italy
Prior art keywords
astaxantin
preparation
synthesis procedure
intermediate synthesis
procedure
Prior art date
Application number
IT002486A
Other languages
English (en)
Inventor
Negra Federico Della
Marco Fachini
Gabriella Santoni
Milan Soukup
Mariano Stivanello
Original Assignee
Italiana Sint Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italiana Sint Spa filed Critical Italiana Sint Spa
Priority to IT002486A priority Critical patent/ITMI20052486A1/it
Priority to PCT/IT2006/000835 priority patent/WO2007072529A2/en
Priority to ARP060105795A priority patent/AR058750A1/es
Publication of ITMI20052486A1 publication Critical patent/ITMI20052486A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/04—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C07C403/16—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms not being part of —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5428—Acyclic unsaturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
IT002486A 2005-12-23 2005-12-23 Procedimento di sintesi di intermedi per la preparazione di astaxantina ITMI20052486A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT002486A ITMI20052486A1 (it) 2005-12-23 2005-12-23 Procedimento di sintesi di intermedi per la preparazione di astaxantina
PCT/IT2006/000835 WO2007072529A2 (en) 2005-12-23 2006-12-04 Process for the synthesis of intermediates for the preparation of astaxanthin
ARP060105795A AR058750A1 (es) 2005-12-23 2006-12-26 Procedimiento para la sintesis de productos intermedios para la preparacion de astaxantina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002486A ITMI20052486A1 (it) 2005-12-23 2005-12-23 Procedimento di sintesi di intermedi per la preparazione di astaxantina

Publications (1)

Publication Number Publication Date
ITMI20052486A1 true ITMI20052486A1 (it) 2007-06-24

Family

ID=38006882

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002486A ITMI20052486A1 (it) 2005-12-23 2005-12-23 Procedimento di sintesi di intermedi per la preparazione di astaxantina

Country Status (3)

Country Link
AR (1) AR058750A1 (it)
IT (1) ITMI20052486A1 (it)
WO (1) WO2007072529A2 (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535323A (en) 2002-02-25 2008-02-29 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
EP2540696B1 (en) 2005-02-24 2020-01-01 Diffusion Pharmaceuticals LLC Trans carotenoids, formulation and uses
JP2011502125A (ja) 2007-10-31 2011-01-20 ディフュージョン・ファーマシューティカルズ・エルエルシー 小分子拡散を促進する新しい種類の治療法
JP5597895B2 (ja) * 2008-05-30 2014-10-01 ディーエスエム アイピー アセッツ ビー．ブイ． アスタキサンチンの結晶形
RU2011101535A (ru) * 2008-06-18 2012-07-27 Лексикон Фармасьютикалз, Инк. (Us) Твердые формы (1r, 2s, 3r)-1-(2-изоксазол-3-ил)-1н-имидазол-4-ил)бутан-1, 2, 3, 4-тетраола и способы их применения
CA2765697C (en) 2009-06-22 2019-11-12 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use alone or with thrombolytics
CN101805249B (zh) * 2010-04-07 2012-12-19 湖南中烟工业有限责任公司 一种合成氧代α或β-紫罗兰酮的方法
AU2011262361A1 (en) 2010-06-02 2013-01-10 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
US9061982B2 (en) 2011-11-09 2015-06-23 Basf Se Process for the preparation of oxovinylionol and its O-protected derivatives
MY168427A (en) * 2011-11-09 2018-11-09 Basf Se Method for producing oxo-vinyl-ionol and o-protected derivatives thereof
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
CN103245658B (zh) * 2013-04-23 2015-07-29 山西省食品质量安全监督检验研究院 一种面包中溴酸盐的快速检测方法
WO2015067707A1 (en) * 2013-11-07 2015-05-14 Dsm Ip Assets B.V. Process for the purification of astaxanthin
WO2015067705A1 (en) * 2013-11-07 2015-05-14 Dsm Ip Assets B.V. Process for the purification of astaxanthin
CN109965279A (zh) * 2013-11-07 2019-07-05 帝斯曼知识产权资产管理有限公司 包含合成的食品级虾青素的粉状制剂、油质悬浮物和膳食补充剂
CN105705041B (zh) * 2013-11-07 2019-07-30 帝斯曼知识产权资产管理有限公司 纯化虾青素的方法
CN105705042B (zh) * 2013-11-07 2018-11-09 帝斯曼知识产权资产管理有限公司 纯化虾青素的方法
CN115089569A (zh) 2016-03-24 2022-09-23 扩散药品有限公司 双极性反式类胡萝卜素连同化疗和放射治疗在治疗癌症中的用途
CN107739390B (zh) * 2017-09-29 2019-08-20 上虞新和成生物化工有限公司 一种虾青素中间体的合成方法
CN109503545B (zh) * 2018-11-30 2020-10-23 彩客化学(沧州)有限公司 一种1,4-环己二酮单乙二醇缩酮的制备方法
CN111302925B (zh) * 2020-03-16 2023-05-30 万华化学集团股份有限公司 一种制备环状α,β-不饱和酮的方法
CN112409155A (zh) * 2020-10-28 2021-02-26 肇庆巨元生化有限公司 一种4-氧代-β-紫罗兰酮的制备方法
CN114940644B (zh) * 2022-06-20 2024-04-09 万华化学集团股份有限公司 一种2,7-二甲基-2,4,6-辛三烯-1,8-二醛的结晶方法

Also Published As

Publication number Publication date
WO2007072529A3 (en) 2007-11-22
AR058750A1 (es) 2008-02-20
WO2007072529A2 (en) 2007-06-28

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