CN112004923A - 细胞组合物及治疗方法 - Google Patents
细胞组合物及治疗方法 Download PDFInfo
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- CN112004923A CN112004923A CN201880083837.3A CN201880083837A CN112004923A CN 112004923 A CN112004923 A CN 112004923A CN 201880083837 A CN201880083837 A CN 201880083837A CN 112004923 A CN112004923 A CN 112004923A
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- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1352—Mesenchymal stem cells
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411189619.1A CN119033819A (zh) | 2017-11-22 | 2018-11-21 | 细胞组合物及治疗方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762589764P | 2017-11-22 | 2017-11-22 | |
| US62/589,764 | 2017-11-22 | ||
| PCT/IB2018/001439 WO2019102268A1 (en) | 2017-11-22 | 2018-11-21 | Cellular compositions and methods of treatment i |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411189619.1A Division CN119033819A (zh) | 2017-11-22 | 2018-11-21 | 细胞组合物及治疗方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112004923A true CN112004923A (zh) | 2020-11-27 |
Family
ID=65003422
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411189619.1A Pending CN119033819A (zh) | 2017-11-22 | 2018-11-21 | 细胞组合物及治疗方法 |
| CN201880083837.3A Pending CN112004923A (zh) | 2017-11-22 | 2018-11-21 | 细胞组合物及治疗方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411189619.1A Pending CN119033819A (zh) | 2017-11-22 | 2018-11-21 | 细胞组合物及治疗方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12473547B2 (enExample) |
| EP (1) | EP3714038A1 (enExample) |
| JP (2) | JP7463275B2 (enExample) |
| KR (2) | KR20200088445A (enExample) |
| CN (2) | CN119033819A (enExample) |
| AU (1) | AU2018372631B2 (enExample) |
| BR (1) | BR112020010079A2 (enExample) |
| CA (1) | CA3084575A1 (enExample) |
| SG (1) | SG11202004680UA (enExample) |
| WO (1) | WO2019102268A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112654705A (zh) * | 2018-09-11 | 2021-04-13 | 德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) | 用在治疗代谢疾病中的微小rna抑制剂 |
| CN113025714A (zh) * | 2021-03-23 | 2021-06-25 | 华中科技大学同济医学院附属同济医院 | 用于甲状腺乳头状癌颈侧方淋巴结转移诊断的miRNA生物标志物及检测试剂盒 |
| CN113621708A (zh) * | 2020-03-30 | 2021-11-09 | 中国医学科学院肿瘤医院 | 用于肺癌诊断的试剂盒、装置及方法 |
| CN118831092A (zh) * | 2024-09-19 | 2024-10-25 | 天津市第五中心医院 | miR-200b-3p在制备治疗子宫内膜癌的药物中的应用 |
| CN119144728A (zh) * | 2024-11-19 | 2024-12-17 | 四川大学华西医院 | 原发性肝癌的MicroRNA标志物的引物、试剂盒和应用 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070258963A1 (en) | 2006-01-13 | 2007-11-08 | Osiris Therapeutics, Inc. | Mesenchymal stem cells expressing TNF-alpha receptors |
| WO2012048099A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Nanoparticle-loaded cells |
| EP3714038A1 (en) | 2017-11-22 | 2020-09-30 | Mesoblast International Sàrl | Cellular compositions and methods of treatment i |
| CN112067805B (zh) * | 2020-08-25 | 2023-08-22 | 南通大学 | 一种β-1,4-半乳糖基转移酶-IsiRNA在克服肝癌化疗耐药药物中的应用 |
| WO2023019128A1 (en) * | 2021-08-09 | 2023-02-16 | The Trustees Of The University Of Pennyslvania | Optimizing t cell differentiation state with micrornas |
| CN114085817B (zh) * | 2021-11-26 | 2025-04-15 | 三代康年(上海)医疗科技有限公司 | 一种包载microRNA的外泌体的制备方法及其产品和应用 |
| US20250333758A1 (en) * | 2021-12-15 | 2025-10-30 | Genans Biotechnology Co., Ltd | Microglia having car and use thereof |
| US20240318185A1 (en) * | 2023-03-20 | 2024-09-26 | MAM Holdings of West Florida, L.L.C. | Mesenchymal stem cell-derived microribonucleic acid-mediated treatments for the prevention and targeted treatment of cancer and other disorders |
Citations (6)
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| WO2008141177A1 (en) * | 2007-05-11 | 2008-11-20 | The Trustees Of Columbia University In The City Ofnew York | Methods and compositions for the treatment of sarcoma |
| US20090163434A1 (en) * | 2006-12-08 | 2009-06-25 | Bader Andreas G | miR-20 Regulated Genes and Pathways as Targets for Therapeutic Intervention |
| US20120114618A1 (en) * | 2009-03-26 | 2012-05-10 | The Regents Of The University Of California | Mesenchymal Stem Cells Producing Inhibitory RNA for Disease Modification |
| US20150024966A1 (en) * | 2012-02-22 | 2015-01-22 | Brainstem Biotec Ltd. | Mesenchymal stem cells for in vitro modeling and cell-based therapy of human diseases and banks thereof |
| US20150329875A1 (en) * | 2014-05-13 | 2015-11-19 | Sangamo Biosciences, Inc. | Methods and compositions for prevention or treatment of a disease |
| WO2017165641A1 (en) * | 2016-03-23 | 2017-09-28 | The Trustees Of Columbia University In The City Of New York | CANCER TREATMENT BASED ON DELIVERY OF OLIGOES VIA GAP JUNCTIONS FROM HUMAN MESENCHYMAL STEM CELLS (hMSC) |
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| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5226914A (en) | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
| US5197985A (en) | 1990-11-16 | 1993-03-30 | Caplan Arnold I | Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells |
| WO1995002698A1 (en) | 1993-07-12 | 1995-01-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
| US5591625A (en) | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
| ATE247933T1 (de) | 1994-06-06 | 2003-09-15 | Univ Case Western Reserve | Biomatrix für geweberegenaration |
| US5736396A (en) | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
| US5643736A (en) | 1995-02-06 | 1997-07-01 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human osteogenic cell surface antigens |
| EP0871457B1 (en) | 1995-03-28 | 2003-05-28 | Thomas Jefferson University | Isolated stromal cells and methods of using the same |
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| CN112654705A (zh) * | 2018-09-11 | 2021-04-13 | 德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) | 用在治疗代谢疾病中的微小rna抑制剂 |
| CN112654705B (zh) * | 2018-09-11 | 2024-07-02 | 德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) | 用在治疗代谢疾病中的微小rna抑制剂 |
| CN113621708A (zh) * | 2020-03-30 | 2021-11-09 | 中国医学科学院肿瘤医院 | 用于肺癌诊断的试剂盒、装置及方法 |
| CN113621708B (zh) * | 2020-03-30 | 2022-02-15 | 中国医学科学院肿瘤医院 | 用于肺癌诊断的试剂盒、装置及方法 |
| CN113025714A (zh) * | 2021-03-23 | 2021-06-25 | 华中科技大学同济医学院附属同济医院 | 用于甲状腺乳头状癌颈侧方淋巴结转移诊断的miRNA生物标志物及检测试剂盒 |
| CN113025714B (zh) * | 2021-03-23 | 2022-05-24 | 华中科技大学同济医学院附属同济医院 | 用于甲状腺乳头状癌颈侧方淋巴结转移诊断的miRNA生物标志物及检测试剂盒 |
| CN118831092A (zh) * | 2024-09-19 | 2024-10-25 | 天津市第五中心医院 | miR-200b-3p在制备治疗子宫内膜癌的药物中的应用 |
| CN119144728A (zh) * | 2024-11-19 | 2024-12-17 | 四川大学华西医院 | 原发性肝癌的MicroRNA标志物的引物、试剂盒和应用 |
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| US12473547B2 (en) | 2025-11-18 |
| BR112020010079A2 (pt) | 2020-11-03 |
| JP7463275B2 (ja) | 2024-04-08 |
| AU2018372631A1 (en) | 2020-05-21 |
| SG11202004680UA (en) | 2020-06-29 |
| CN119033819A (zh) | 2024-11-29 |
| JP2021507683A (ja) | 2021-02-25 |
| WO2019102268A1 (en) | 2019-05-31 |
| KR20250051794A (ko) | 2025-04-17 |
| AU2018372631B2 (en) | 2025-06-05 |
| CA3084575A1 (en) | 2019-05-31 |
| EP3714038A1 (en) | 2020-09-30 |
| US20210163932A1 (en) | 2021-06-03 |
| KR20200088445A (ko) | 2020-07-22 |
| JP2024091644A (ja) | 2024-07-05 |
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