MX366900B - Métodos y materiales para diferenciación hematoendotelial de células germinales pluripotentes humanas bajo condiciones definidas. - Google Patents
Métodos y materiales para diferenciación hematoendotelial de células germinales pluripotentes humanas bajo condiciones definidas.Info
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- MX366900B MX366900B MX2015012202A MX2015012202A MX366900B MX 366900 B MX366900 B MX 366900B MX 2015012202 A MX2015012202 A MX 2015012202A MX 2015012202 A MX2015012202 A MX 2015012202A MX 366900 B MX366900 B MX 366900B
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1394—Bone marrow stromal cells; whole marrow
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Health & Medical Sciences (AREA)
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- Biochemistry (AREA)
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- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a métodos y composiciones para diferenciar células germinales pluripotentes en células de linajes endoteliales y hematopoyéticas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779564P | 2013-03-13 | 2013-03-13 | |
| PCT/US2014/024518 WO2014165131A1 (en) | 2013-03-13 | 2014-03-12 | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012202A MX2015012202A (es) | 2015-11-30 |
| MX366900B true MX366900B (es) | 2019-07-30 |
Family
ID=50678273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012202A MX366900B (es) | 2013-03-13 | 2014-03-12 | Métodos y materiales para diferenciación hematoendotelial de células germinales pluripotentes humanas bajo condiciones definidas. |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9938499B2 (es) |
| EP (1) | EP2970912B1 (es) |
| JP (1) | JP6677631B2 (es) |
| KR (1) | KR102151210B1 (es) |
| CN (1) | CN105209609B (es) |
| AU (1) | AU2014248651B2 (es) |
| BR (1) | BR112015022770B1 (es) |
| CA (2) | CA2905786C (es) |
| DK (1) | DK2970912T3 (es) |
| ES (1) | ES2720196T3 (es) |
| HU (1) | HUE043785T2 (es) |
| IL (1) | IL241286B (es) |
| MX (1) | MX366900B (es) |
| PL (1) | PL2970912T3 (es) |
| PT (1) | PT2970912T (es) |
| SG (1) | SG11201507275TA (es) |
| TR (1) | TR201904270T4 (es) |
| WO (1) | WO2014165131A1 (es) |
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| US11220672B2 (en) * | 2014-12-31 | 2022-01-11 | Wisconsin Alumni Research Foundation | Human pluripotent stem cell-based system for generating endothelial cells |
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| CN113046318B (zh) * | 2021-04-13 | 2023-04-18 | 中国科学院深圳先进技术研究院 | 一种诱导多能干细胞向造血前体细胞分化的培养基以及方法 |
| CN117836405A (zh) * | 2021-08-13 | 2024-04-05 | 先声创新公司 | 三维培养多能干细胞产生造血干细胞 |
| IL316055A (en) | 2022-04-15 | 2024-11-01 | Aspen Neuroscience Inc | Methods of classifying the differentiation state of cells and related compositions of differentiated cells |
| KR20250160941A (ko) * | 2023-02-16 | 2025-11-14 | 신택스 바이오, 인크. | 조혈 계통으로의 세포 프로그래밍을 위한 시스템 및 이의 방법 |
| WO2025184351A1 (en) * | 2024-03-01 | 2025-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | A method to generate endothelial cells |
| CN120173879A (zh) * | 2025-05-13 | 2025-06-20 | 细胞生态海河实验室 | 一种由多能干细胞向造血干祖细胞分化的培养基组合物、其使用方法和应用 |
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| US8034613B2 (en) | 2005-06-01 | 2011-10-11 | Wisconsin Alumni Research Foundation | Multipotent lymphohematopoietic progenitor cells |
| JP2008541762A (ja) | 2005-06-01 | 2008-11-27 | ウイスコンシン アラムナイ リサーチ フオンデーシヨン | 胚性幹細胞から樹状細胞を生成する方法 |
| GB2449042B (en) | 2006-02-09 | 2010-07-07 | Wisconsin Alumni Res Found | Erythroid cells producing adult-type b-hemoglobin generated from human embryonic stem cells |
| AU2008231020B2 (en) | 2007-03-23 | 2013-09-05 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
| US20110236971A2 (en) | 2007-09-25 | 2011-09-29 | Maksym Vodyanyk | Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions |
| US7615374B2 (en) | 2007-09-25 | 2009-11-10 | Wisconsin Alumni Research Foundation | Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions |
| WO2009072990A1 (en) | 2007-12-06 | 2009-06-11 | Agency For Science, Technology And Research | Method for extracellular matrix mediated differentiation and proliferation of stem cells |
| KR20210003301A (ko) * | 2008-05-06 | 2021-01-11 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 다능성 줄기세포로부터 유도된 탈핵 적혈구계 세포를 생산하는 방법 |
| US8372642B2 (en) | 2009-02-27 | 2013-02-12 | Cellular Dynamics International, Inc. | Differentiation of pluripotent cells |
| WO2010143529A1 (ja) * | 2009-06-09 | 2010-12-16 | 国立大学法人名古屋大学 | 多能性幹細胞を胸腺上皮へ分化誘導する方法 |
| EP2563908B1 (en) * | 2010-04-25 | 2019-01-09 | Icahn School of Medicine at Mount Sinai | Generation of anterior foregut endoderm from pluripotent cells |
| US9279107B2 (en) | 2010-08-05 | 2016-03-08 | Wisconsin Alumni Research Foundation | Simplified basic media for human pluripotent cell culture |
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