CN109689686B - 使用融合蛋白进行t细胞受体重编程的组合物和方法 - Google Patents

使用融合蛋白进行t细胞受体重编程的组合物和方法 Download PDF

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CN109689686B
CN109689686B CN201780039623.1A CN201780039623A CN109689686B CN 109689686 B CN109689686 B CN 109689686B CN 201780039623 A CN201780039623 A CN 201780039623A CN 109689686 B CN109689686 B CN 109689686B
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cells
tfp
cell
mesothelin
tcr
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CN109689686A (zh
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帕特里克·博伊尔勒
格雷戈里·西兹克维克兹
罗伯特·霍夫梅斯特
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TCR2 Therapeutics Inc
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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CN201780039623.1A 2016-10-07 2017-10-06 使用融合蛋白进行t细胞受体重编程的组合物和方法 Expired - Fee Related CN109689686B (zh)

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PCT/US2017/055628 WO2018067993A1 (en) 2016-10-07 2017-10-06 Compositions and methods for t-cell receptors reprogramming using fusion proteins

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