CN107019804A - 靶向吡咯并苯并二氮杂卓结合物 - Google Patents

靶向吡咯并苯并二氮杂卓结合物 Download PDF

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Publication number
CN107019804A
CN107019804A CN201611198713.9A CN201611198713A CN107019804A CN 107019804 A CN107019804 A CN 107019804A CN 201611198713 A CN201611198713 A CN 201611198713A CN 107019804 A CN107019804 A CN 107019804A
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China
Prior art keywords
group
acid
conjugate according
attachment point
bases
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CN201611198713.9A
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Chinese (zh)
Inventor
菲利普·威尔逊·霍华德
斯科特·杰弗里
帕特里克·伯克
彼得·森特
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ADC Therapeutics SA
Seagen Inc
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ADC Therapeutics SA
Seattle Genetics Inc
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Publication of CN107019804A publication Critical patent/CN107019804A/zh
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    • C07D519/06—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 containing at least one condensed beta-lactam ring system, provided for by groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00, e.g. a penem or a cepham system
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