CN106987532B - 提高脂肪酸衍生物的产量 - Google Patents

提高脂肪酸衍生物的产量 Download PDF

Info

Publication number
CN106987532B
CN106987532B CN201710052351.0A CN201710052351A CN106987532B CN 106987532 B CN106987532 B CN 106987532B CN 201710052351 A CN201710052351 A CN 201710052351A CN 106987532 B CN106987532 B CN 106987532B
Authority
CN
China
Prior art keywords
gene
acyl
fatty
fatty acid
bacterial cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201710052351.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN106987532A (zh
Inventor
胡志浩
费尔南多·瓦勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genomatica Inc
Original Assignee
Genomatica Inc
REG Life Sciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39712152&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106987532(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2007/011923 external-priority patent/WO2007136762A2/en
Application filed by Genomatica Inc, REG Life Sciences LLC filed Critical Genomatica Inc
Publication of CN106987532A publication Critical patent/CN106987532A/zh
Application granted granted Critical
Publication of CN106987532B publication Critical patent/CN106987532B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/649—Biodiesel, i.e. fatty acid alkyl esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0105—Long-chain-fatty-acyl-CoA reductase (1.2.1.50)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/99—Oxidoreductases acting on the CH-CH group of donors (1.3) with other acceptors (1.3.99)
    • C12Y103/99003—Acyl-CoA dehydrogenase (1.3.99.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01075—Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/02—Thioester hydrolases (3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y602/00—Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
    • C10G2300/00—Aspects relating to hydrocarbon processing covered by groups C10G1/00 - C10G99/00
    • C10G2300/10—Feedstock materials
    • C10G2300/1011—Biomass
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/59—Biological synthesis; Biological purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P30/00—Technologies relating to oil refining and petrochemical industry
    • Y02P30/20—Technologies relating to oil refining and petrochemical industry using bio-feedstock

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Liquid Carbonaceous Fuels (AREA)
CN201710052351.0A 2007-03-28 2008-03-28 提高脂肪酸衍生物的产量 Expired - Fee Related CN106987532B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US90854707P 2007-03-28 2007-03-28
US60/908,547 2007-03-28
USPCT/US2007/011923 2007-05-18
PCT/US2007/011923 WO2007136762A2 (en) 2006-05-19 2007-05-18 Production of fatty acids and derivatives thereof
US98979807P 2007-11-21 2007-11-21
US60/989,798 2007-11-21
CN200880009283.9A CN101680009B (zh) 2007-03-28 2008-03-28 提高脂肪酸衍生物的产量

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880009283.9A Division CN101680009B (zh) 2007-03-28 2008-03-28 提高脂肪酸衍生物的产量

Publications (2)

Publication Number Publication Date
CN106987532A CN106987532A (zh) 2017-07-28
CN106987532B true CN106987532B (zh) 2021-06-08

Family

ID=39712152

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201710052351.0A Expired - Fee Related CN106987532B (zh) 2007-03-28 2008-03-28 提高脂肪酸衍生物的产量
CN200880009283.9A Expired - Fee Related CN101680009B (zh) 2007-03-28 2008-03-28 提高脂肪酸衍生物的产量

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200880009283.9A Expired - Fee Related CN101680009B (zh) 2007-03-28 2008-03-28 提高脂肪酸衍生物的产量

Country Status (10)

Country Link
EP (3) EP2594633A1 (de)
JP (4) JP5863088B2 (de)
KR (1) KR20100015763A (de)
CN (2) CN106987532B (de)
AU (1) AU2008230735A1 (de)
BR (1) BRPI0809345A2 (de)
CA (3) CA3035878C (de)
ES (1) ES2536405T5 (de)
MX (1) MX2009009371A (de)
WO (1) WO2008119082A2 (de)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
KR101862691B1 (ko) 2007-05-22 2018-05-31 알이지 라이프 사이언시스, 엘엘씨 탄화수소-생산 유전자와 이들의 이용 방법
WO2009009391A2 (en) * 2007-07-06 2009-01-15 Ls9, Inc. Systems and methods for the production of fatty esters
US8313934B2 (en) 2007-09-27 2012-11-20 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
MX2010006539A (es) 2007-12-11 2011-02-23 Synthetic Genomics Inc Secrecion de acidos grasos por parte de microorganismos fotosinteticos.
US8183028B2 (en) 2007-12-21 2012-05-22 Ls9, Inc. Methods and compositions for producing olefins
US8048654B2 (en) 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
EP3450550A1 (de) 2008-03-05 2019-03-06 Genomatica, Inc. Primäre, alkohole produzierende organismen
GB0807619D0 (en) 2008-04-28 2008-06-04 Whitton Peter A Production of bio fuels from plant tissue culture sources
CA3101888A1 (en) * 2008-05-16 2009-11-19 REG Life Sciences, LLC Methods and compositions for producing hydrocarbons
WO2010022090A1 (en) * 2008-08-18 2010-02-25 Ls9, Inc. Systems and methods for the production of mixed fatty esters
US8097439B2 (en) 2008-10-07 2012-01-17 Ls9, Inc. Methods and compositions for producing fatty aldehydes
US9896642B2 (en) 2008-10-14 2018-02-20 Corbion Biotech, Inc. Methods of microbial oil extraction and separation
WO2010048568A1 (en) 2008-10-23 2010-04-29 Targeted Growth, Inc. Modified photosynthetic microorganisms for producing triglycerides
CN105154380B (zh) 2008-10-28 2018-11-09 Reg生命科学有限责任公司 用于产生脂肪醇的方法和组合物
CA2747516C (en) 2008-12-23 2019-11-05 Ls9, Inc. Methods and compositions related to thioesterase enzymes
US8835137B2 (en) 2008-12-23 2014-09-16 Matrix Genetics, Llc Modified photosynthetic microorganisms with reduced glycogen and their use in producing carbon-based products
CA2758301A1 (en) * 2009-04-10 2010-10-14 Ls9, Inc. Production of fatty acid derivatives
EP2425007A4 (de) * 2009-04-27 2013-01-02 Ls9 Inc Herstellung von fettsäureestern
AU2010254104A1 (en) * 2009-05-26 2011-12-15 Solazyme, Inc. Fractionation of oil-bearing microbial biomass
BRPI1014338B1 (pt) 2009-06-25 2019-12-24 Shell Int Research método para injetar água em uma formação contendo hidrocarbonetos, e, método para preparar uma água com salinidade elevada
US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
US7955820B1 (en) 2009-07-09 2011-06-07 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
WO2011011568A2 (en) * 2009-07-24 2011-01-27 The Regenst Of The University Of California Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms
WO2011019858A1 (en) * 2009-08-11 2011-02-17 Synthetic Genomics, Inc. Microbial production of fatty alcohols
MX2012003472A (es) 2009-09-25 2012-05-22 Ls9 Inc Produccion de derivados de acido graso.
US8450090B2 (en) * 2009-10-06 2013-05-28 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for promoting fatty acid production in plants
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
EP2524035A2 (de) * 2010-01-15 2012-11-21 Shell Internationale Research Maatschappij B.V. Konstrukte, vektoren und cyanobakterien für die synthese von fettalkoholen und verfahren zur herstellung von fettalkoholen bei cyanobakterien
CN102311966B (zh) * 2010-06-30 2016-04-13 中国科学院青岛生物能源与过程研究所 用于合成脂肪醇的构建体，载体，蓝细菌，以及在蓝细菌中生产脂肪醇的方法
WO2011100667A1 (en) 2010-02-14 2011-08-18 Ls9, Inc. Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols
WO2011127069A1 (en) * 2010-04-06 2011-10-13 Targeted Growth, Inc. Modified photosynthetic microorganisms for producing lipids
AR084377A1 (es) * 2010-04-08 2013-05-15 Ls9 Inc Metodos y composiciones relacionados con enzimas de alcohol graso biosintetico
WO2011155799A2 (ko) * 2010-06-10 2011-12-15 한국과학기술원 탄화수소 생성능을 가지는 변이 미생물 및 이를 이용한 탄화수소의 제조방법
PT3401410T (pt) 2010-06-26 2021-04-05 Virdia Llc Métodos para produção de misturas de açúcar
CN103687583B (zh) 2010-07-15 2016-08-17 宝洁公司 清洁毛发的方法
US20120172281A1 (en) 2010-07-15 2012-07-05 Jeffrey John Scheibel Detergent compositions comprising microbially produced fatty alcohols and derivatives thereof
WO2012017083A1 (en) 2010-08-06 2012-02-09 Jens Nielsen Methods and products for production of wax esters
US8372610B2 (en) 2010-09-15 2013-02-12 Ls9, Inc. Production of odd chain fatty acid derivatives in recombinant microbial cells
WO2012047832A2 (en) 2010-10-07 2012-04-12 Shell Oil Company Process for the production of alcohols from biomass
US20120108692A1 (en) 2010-10-27 2012-05-03 John Collins Dyer Preparation of foam materials derived from renewable resources
WO2012061596A1 (en) 2010-11-05 2012-05-10 Shell Oil Company Treating biomass to produce materials useful for biofuels
PL2465868T3 (pl) 2010-12-17 2016-08-31 Neste Oyj Ulepszenie produkcji lipidów
US8609379B2 (en) 2010-12-20 2013-12-17 Shell Oil Company Process for the production of alcohols from biomass
US9187726B2 (en) 2010-12-23 2015-11-17 Exxonmobil Research And Engineering Company Culturing a microorganism in a medium with an elevated level of a carboxylate counterion source
EP2655615A4 (de) * 2010-12-23 2014-04-23 Exxonmobil Res & Eng Co Prokaryotische acyl-acp-thioesterasen zur herstellung von fettsäuren in genetisch modifizierten mikroorganismen
PL2655612T3 (pl) 2010-12-23 2017-12-29 Shell Internationale Research Maatschappij B.V. Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa
EP2658963A4 (de) * 2010-12-31 2014-05-14 Exxonmobil Res & Eng Co Verbesserung der biomasseproduktion durch disruption von lichtenergiedissipationswegen
CA2823928C (en) 2011-01-14 2020-09-22 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
WO2012138423A1 (en) 2011-02-17 2012-10-11 The Procter & Gamble Company Compositions comprising mixtures of c10-c13 alkylphenyl sulfonates
MX2013009546A (es) 2011-02-17 2013-11-22 Procter & Gamble Alquilfenil sulfonatos lineales de base biologica.
US9029124B2 (en) 2011-03-23 2015-05-12 Joule Unlimited Technologies, Inc. Photoalkanogens with increased productivity
US20140215904A1 (en) 2011-03-30 2014-08-07 Ls9, Inc. Compositions comprising and methods for producing beta-hydroxy fatty acid esters
SI2906587T1 (sl) 2011-04-01 2020-12-31 Genomatica, Inc. Metode in sestave za izboljšano proizvodnjo maščobnih kislin in njihovih derivatov
MX2013015327A (es) 2011-06-30 2014-01-31 Exxonmobil Res & Eng Co Regulacion de genes toxina y antitoxina para contencion biologica.
BR112014002624A8 (pt) * 2011-08-03 2017-07-04 Ls9 Inc Microorganismo recombinante e cultura de microorganismo recombinante
DE102011110945A1 (de) 2011-08-15 2013-02-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt
DE102011110946A1 (de) 2011-08-15 2016-01-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen
ES2396823B1 (es) * 2011-08-18 2014-01-28 Iden Biotechnology S.L. Producción de biodiesel a partir de glicerina.
CN102952818B (zh) * 2011-08-26 2016-03-02 中国科学院青岛生物能源与过程研究所 用于在蓝细菌中提高脂肪醇产量的构建体和方法
CN103975070A (zh) 2011-09-27 2014-08-06 艾克森美孚研究与工程公司 酰基-酰基载体蛋白(acyl-acp)蜡酯合酶
PL2791344T3 (pl) 2011-12-15 2016-08-31 Shell Int Research Sposób obróbki produktów ubocznych z wytwarzania etanolu
US20140357727A1 (en) 2011-12-20 2014-12-04 Codexis, Inc. Fatty alcohol forming acyl reductase (far) variants and methods of use
EP2820029A4 (de) * 2012-02-29 2015-12-23 Exxonmobil Res & Eng Co Vier-gene-signalweg für wachsestersynthese
US8962299B2 (en) 2012-02-29 2015-02-24 Exxonmobil Research And Engineering Company Four-gene pathway for wax ester synthesis
KR101407233B1 (ko) * 2012-03-05 2014-06-16 한국생명공학연구원 보트리오코커스 브라우니의 생장 촉진 및 지방산 함량 증가 특성을 가진 신규 미생물 리조비움 속 ｋｂ１０
WO2013152052A2 (en) 2012-04-02 2013-10-10 Ls9, Inc. Novel car enzymes and improved production of fatty alcohols
CA2883968C (en) 2012-04-02 2022-08-23 REG Life Sciences, LLC Improved production of fatty acid derivatives
US9163267B2 (en) 2012-04-11 2015-10-20 REG Life Sciences, LLC Metathesis transformations of microbially-produced fatty acids and fatty acid derivatives
KR102278343B1 (ko) * 2012-04-13 2021-07-16 게노마티카 인코포레이티드 알카놀아미드들 및 아미도아민들의 미생물에 의한 생산 및 이의 용도
US20150133698A1 (en) 2012-04-20 2015-05-14 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
BR112014027355B1 (pt) 2012-05-07 2020-12-29 Shell Internationale Research Maatschappij B.V. processo contínuo ou semicontínuo para tratar biomassa
DE102012207921A1 (de) 2012-05-11 2013-11-14 Evonik Industries Ag Mehrstufiges Syntheseverfahren mit Synthesegas
AU2013262757B2 (en) 2012-05-17 2015-06-25 Shell Internationale Research Maatschappij B.V. Process for producing volatile organic compounds from biomass material
AU2013262758B9 (en) 2012-05-17 2015-11-12 Shell Internationale Research Maatschappij B.V. Process for producing volatile organic compounds from biomass material
JP2015517824A (ja) * 2012-05-29 2015-06-25 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 生合成経路、組み換え細胞、及び方法
US9347076B2 (en) * 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
MY172692A (en) 2012-07-13 2019-12-10 Calysta Inc Biorefinery system, methods and compositions thereof
WO2014015278A1 (en) 2012-07-20 2014-01-23 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
US9909153B2 (en) 2012-11-09 2018-03-06 Calysta, Inc. Compositions and methods for biological production of fatty acid derivatives
WO2014093505A2 (en) 2012-12-12 2014-06-19 Ls9, Inc. Acp-mediated production of fatty acid derivatives
US9512447B2 (en) 2012-12-14 2016-12-06 Codexis, Inc. Modified native beta-ketoacyl-ACP synthases and engineered microorganisms
WO2014113571A2 (en) 2013-01-16 2014-07-24 Ls9, Inc. Acyl-acp reductase with improved properties
KR102363796B1 (ko) * 2013-03-07 2022-02-16 게노마티카 인코포레이티드 재조합 숙주 세포에 의해 생성된 지방알코올 조성물들의 하류 공정
MY203897A (en) 2013-06-14 2024-07-23 Genomatica Inc Methods of producing omega-hydroxylated fatty acid derivatives
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
JP6603658B2 (ja) * 2013-07-19 2019-11-06 カーギル インコーポレイテッド 脂肪酸及び脂肪酸誘導体の製造のための微生物及び方法
BR112016012371B1 (pt) * 2013-12-05 2023-03-28 Genomatica, Inc Célula bacteriana recombinante para a produção de uma amina graxa, cultura de células e método de produção de uma amina graxa
JP6379537B2 (ja) * 2014-03-12 2018-08-29 東ソー株式会社 組換え水素酸化細菌およびそれを用いたタンパク質製造方法
US20150299739A1 (en) 2014-04-17 2015-10-22 Shell Oil Company Processes for producing fermentation products
KR101879904B1 (ko) * 2014-04-17 2018-07-19 서강대학교산학협력단 지방산 함량 개선을 위한 형질전환 효모 및 그의 제조방법
EP2944697A1 (de) 2014-05-13 2015-11-18 Evonik Degussa GmbH Verfahren zur Herstellung von Nylon
EP2944696A1 (de) 2014-05-13 2015-11-18 Evonik Degussa GmbH Verfahren zur Herstellung von organischen Verbindungen
US11441130B2 (en) 2014-06-16 2022-09-13 Genomatica, Inc. Omega-hydroxylase-related fusion polypeptides with improved properties
WO2016004473A1 (en) 2014-07-07 2016-01-14 Commonwealth Scientific And Industrial Research Organisation Processes for producing industrial products from plant lipids
CN106573884B (zh) 2014-08-14 2018-09-28 国际壳牌研究有限公司 处理生物质以生产用于生物燃料的物质的改进方法
WO2016025678A1 (en) 2014-08-14 2016-02-18 Shell Oil Company Process for preparing furfural from biomass
WO2016025673A1 (en) 2014-08-14 2016-02-18 Shell Oil Company Process for preparing furfural from biomass
JP2016054703A (ja) * 2014-09-11 2016-04-21 花王株式会社 ラウリン酸の製造方法
WO2016137897A1 (en) * 2015-02-24 2016-09-01 William Marsh Rice University Kasiii-free fa synthesis
JP2016158523A (ja) * 2015-02-27 2016-09-05 学校法人中部大学 ラン藻の脂肪酸放出株及び脂肪酸耐性株の作出法
CN105985987B (zh) * 2015-03-02 2020-01-31 苏州安捷生物科技有限公司 一种生物法制备脂肪醇的方法
EP3277827B1 (de) * 2015-04-02 2021-03-24 Biopetrolia AB Pilzzellen und verfahren zur herstellung von produkten aus sehr langkettigen fettsäuren
US11291693B2 (en) 2015-06-25 2022-04-05 Synlogic Operating Company, Inc. Bacteria engineered to treat metabolic diseases
CN106318944B (zh) * 2015-06-29 2019-01-22 中国科学院大连化学物理研究所 葡萄糖去阻遏诱导启动子和终止子及其应用
CN106318941B (zh) * 2015-06-29 2019-01-22 中国科学院大连化学物理研究所 一种葡萄糖去阻遏诱导启动子和终止子及其应用
JP6688497B2 (ja) * 2015-10-08 2020-04-28 学校法人明治大学 有機酸の製造方法
KR101743018B1 (ko) 2015-10-22 2017-06-05 한국과학기술연구원 이산화탄소로부터의 바이오디젤 생산능을 갖는 형질전환된 시네코코커스 일롱게투스 균주 및 이를 이용한 바이오디젤 생산방법
EP3376859B1 (de) 2015-11-18 2021-01-06 Provivi, Inc. Mikroorganismen zur herstellung von insektenpheromonen und verwandten verbindungen
EP3173478A1 (de) * 2015-11-25 2017-05-31 Evonik Degussa GmbH Biotechnologische herstellung von omega-funktionalisierten carbonsäuren und ester davon
WO2017101987A1 (en) 2015-12-15 2017-06-22 REG Life Sciences, LLC Omega-hydroxylase-related fusion polypeptide variants with improved properties
ES2803208T3 (es) 2015-12-17 2021-01-25 Evonik Operations Gmbh Una célula acetogénica genéticamente modificada
RU2740758C2 (ru) 2016-05-03 2021-01-20 Шелл Интернэшнл Рисерч Маатсхаппий Б.В. Растворители на основе лигнина и способы их получения
EP3246401A1 (de) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives Neue fettsäuredecarboxylase und deren verwendungen
JP2019517797A (ja) 2016-06-06 2019-06-27 プロヴィヴィ インコーポレイテッド 脂肪アルコールおよび脂肪アルデヒドの半生合成的生産
US10421951B2 (en) 2016-06-22 2019-09-24 Wisconsin Alumni Research Foundation Gene construct encoding mutant thioesterase, mutant thioesterase encoded thereby, transformed host cell containing the gene construct, and method of using them to produce medium-chain fatty acids
WO2018019867A1 (en) 2016-07-27 2018-02-01 Evonik Degussa Gmbh N-acetyl homoserine
US11859193B2 (en) 2016-09-02 2024-01-02 Nuseed Global Innovation Ltd. Plants with modified traits
CN109890800B (zh) 2016-11-01 2023-05-23 国际壳牌研究有限公司 用于回收糠醛的工艺
US10899725B2 (en) 2016-11-01 2021-01-26 Shell Oil Company Process for the recovery of furfural
EP3535248A1 (de) 2016-11-01 2019-09-11 Shell Internationale Research Maatschappij B.V. Verfahren zur rückgewinnung von furfural
EP3535246A1 (de) 2016-11-01 2019-09-11 Shell Internationale Research Maatschappij B.V. Verfahren zur rückgewinnung von furfural
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
CN111094558A (zh) 2017-04-03 2020-05-01 基因组股份公司 对产生中链脂肪酸衍生物具有改善的活性的硫酯酶变体
WO2018213554A1 (en) 2017-05-17 2018-11-22 Provivi, Inc. Microorganisms for the production of insect pheromones and related compounds
US10844410B2 (en) 2018-03-19 2020-11-24 Wisconsin Alumni Research Foundation Mutant thioesterases
EP3794017A4 (de) 2018-05-17 2022-03-09 Lumen Bioscience, Inc. Orale arthrospira-platensis-impfstoffabgabeplattform
CN108753809B (zh) * 2018-06-06 2021-08-17 上海交通大学 一种高效表达脂肪酸的重组蓝藻及其制备方法
WO2019236819A1 (en) * 2018-06-07 2019-12-12 Cargill, Incorporated Methods and genetically modified cells for producing c8 fatty acids and fatty acid chain products
US12252513B2 (en) 2018-07-16 2025-03-18 Lumen Bioscience, Inc. Thermostable phycobiliproteins produced from recombinant arthrospira
KR102117828B1 (ko) 2018-07-19 2020-06-02 서울대학교산학협력단 레귤론 변이를 통한 지방산 및 지방산 유도체 생산에서 불포화도 감소
CN110272839B (zh) * 2019-05-08 2020-10-30 江南大学 一株不动杆菌及其在生产手性3-环己烯-1-甲酸中的应用
EP3972962A1 (de) 2019-05-22 2022-03-30 Shell Internationale Research Maatschappij B.V. Verfahren zur herstellung von furfural
AU2020298626A1 (en) 2019-07-03 2022-02-24 Lumen Bioscience, Inc. Arthrospira platensis non-parenteral therapeutic delivery platform
CN111235170A (zh) * 2020-01-17 2020-06-05 华中农业大学 qMYR2基因在调节或筛选稻米中油脂组分含量的应用
CN112143747B (zh) * 2020-09-09 2022-09-13 昆明理工大学 一种噬菌体裂解酶及其基因、基因重组表达载体与应用
EP4630526A1 (de) 2022-12-05 2025-10-15 The Procter & Gamble Company Stoff- und haushaltspflegezusammensetzung mit einer polyalkylencarbonatverbindung
AU2024212235A1 (en) 2023-01-23 2025-07-03 Shell Internationale Research Maatschappij B.V. Method for treating grains to produce material useful for chemicals and biofuels
CN118726502B (zh) * 2024-07-12 2025-09-12 妆莱控股(苏州)股份有限公司 一种抗坏血酸四异棕榈酸酯的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1064312A (zh) * 1991-02-22 1992-09-09 加利福尼亚基因公司 酯酰还原酶
CN1491282A (zh) * 2000-12-28 2004-04-21 丰田自动车株式会社 异戊二烯醇的制备方法
CN1548527A (zh) * 2003-05-08 2004-11-24 清华大学 产共聚物PHBHHx的重组嗜水气单胞菌及其构建方法与应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3149170A1 (de) * 1980-12-15 1982-07-29 Institut Français du Pétrole, 92502 Rueil-Malmaison, Hauts-de-Seine Brennbare komposition, welche gasoel, methanol und einen fettsaeureester enthalten und als dieseltreibstoff brauchbar sind
US5424202A (en) 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5482846A (en) 1988-08-31 1996-01-09 University Of Florida Ethanol production in Gram-positive microbes
US5028539A (en) 1988-08-31 1991-07-02 The University Of Florida Ethanol production using engineered mutant E. coli
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
JPH02247111A (ja) * 1989-03-18 1990-10-02 Nippon Oil & Fats Co Ltd 養毛・育毛料
US5602030A (en) 1994-03-28 1997-02-11 University Of Florida Research Foundation Recombinant glucose uptake system
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
US6143538A (en) * 1997-02-20 2000-11-07 The United States Of America As Represented By The United States Department Of Energy Fatty acyl-CoA reductase
ES2340915T3 (es) * 2000-11-17 2010-06-11 Metabolix, Inc. Produccion de polihidroxialcanoatos de longitud media de cadena por caminos de biosintesis de acidos grasos.
JP2002223788A (ja) * 2001-01-31 2002-08-13 Kao Corp アルコールの製造方法
US7314974B2 (en) * 2002-02-21 2008-01-01 Monsanto Technology, Llc Expression of microbial proteins in plants for production of plants with improved properties
DE60329983D1 (de) 2002-03-01 2009-12-24 Monsanto Technology Llc Wachsestersynthase-dna-sequenz, protein und verwendungen davon
JP2007502124A (ja) 2003-08-11 2007-02-08 コデクシス， インコーポレイテッド 改良ケトレダクターゼポリペプチドおよび関連ポリヌクレオチド
AU2005212304A1 (en) * 2004-02-09 2005-08-25 O2Diesel Corporation Methods for reducing particulate matter emissions from diesel engine exhaust using ethanol/diesel fuel blends in combination with diesel oxidation catalysts
GB0421937D0 (en) * 2004-10-02 2004-11-03 Univ York Acyl CoA synthetases
DE102004052115A1 (de) * 2004-10-26 2006-04-27 Westfälische Wilhelms-Universität Münster Mikroorganismen zur Herstellung von Fettsäureestern, Verfahren zu deren Herstellung und deren Verwendung
WO2007022169A1 (en) * 2005-08-15 2007-02-22 Arizona Chemical Company Low sulfur tall oil fatty acid
JP4219349B2 (ja) * 2005-09-16 2009-02-04 富士フイルム株式会社 脂肪酸アルキルエステルの製造方法及び燃料

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1064312A (zh) * 1991-02-22 1992-09-09 加利福尼亚基因公司 酯酰还原酶
CN1491282A (zh) * 2000-12-28 2004-04-21 丰田自动车株式会社 异戊二烯醇的制备方法
CN1548527A (zh) * 2003-05-08 2004-11-24 清华大学 产共聚物PHBHHx的重组嗜水气单胞菌及其构建方法与应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Metabolic engineering of Aeromonas hydrophila for the enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate);Qiu et al;《Appl Microbiol Biotechnol》;20061231(第69期);537–542 *

Also Published As

Publication number Publication date
EP3369807A3 (de) 2018-11-21
CN101680009A (zh) 2010-03-24
ES2536405T5 (es) 2022-04-06
CA2678915C (en) 2019-04-09
JP6744705B2 (ja) 2020-08-19
WO2008119082A2 (en) 2008-10-02
JP6925311B2 (ja) 2021-08-25
CA3178593A1 (en) 2008-10-02
MX2009009371A (es) 2009-09-21
EP2129785A2 (de) 2009-12-09
CA3035878C (en) 2023-01-03
CA3035878A1 (en) 2008-10-02
EP2594633A1 (de) 2013-05-22
CN106987532A (zh) 2017-07-28
WO2008119082A3 (en) 2009-03-12
EP3369807A2 (de) 2018-09-05
KR20100015763A (ko) 2010-02-12
BRPI0809345A2 (pt) 2014-10-07
JP2016093174A (ja) 2016-05-26
CN101680009B (zh) 2017-02-22
EP2129785B1 (de) 2015-02-18
JP2019022523A (ja) 2019-02-14
ES2536405T3 (es) 2015-05-25
JP5863088B2 (ja) 2016-02-16
AU2008230735A1 (en) 2008-10-02
JP2021182928A (ja) 2021-12-02
JP2010538602A (ja) 2010-12-16
CA2678915A1 (en) 2008-10-02
EP2129785B2 (de) 2021-11-17

Similar Documents

Publication Publication Date Title
US11046635B2 (en) Recombinant E. coli for enhanced production of fatty acid derivatives
JP6925311B2 (ja) 脂肪酸誘導体の増強された生産
JP6275203B2 (ja) 脂肪酸およびその誘導体の生産
US20170275651A1 (en) Production of fatty acids and derivatives thereof
CN104894044A (zh) 脂肪酸及其衍生物的制备
CN101490241A (zh) 脂肪酸及其衍生物的制备
AU2015238773B2 (en) Production of fatty acids and derivatives thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20191211

Address after: California, USA

Applicant after: GENOMATICA, Inc.

Address before: California, USA

Applicant before: REG Life Sciences, LLC

TA01 Transfer of patent application right
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20210608

CF01 Termination of patent right due to non-payment of annual fee