CN105287859A

CN105287859A - Freshly-squeezed paulownia flower freeze-dried powdery decoction piece and preparation technology thereof

Info

Publication number: CN105287859A
Application number: CN201510807231.8A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-22
Filing date: 2015-11-22
Publication date: 2016-02-03

Abstract

The invention discloses a freshly-squeezed paulownia flower freeze-dried powdery decoction piece and a preparation technology thereof. The preparation technology comprises the following steps: after the paulownia flowers are harvested, picking qualified paulownia flowers, washing selected paulownia flowers, squeezing the fresh paulownia flowers, filtering the juice, adding water into the residues, filtering, squeezing; merging the juice, carrying out reduced pressured concentration, freeze-drying the liquid, collecting the freeze-drying products, grinding the obtained solids, and packaging the powder into vacuum bags. The provided preparation method maximally preserves the polar and non-polar effective components in paulownia flowers. The decoction piece is convenient for transportation, storage, and blending, the quality is controllable, and the curative effect is reliable. The preparation technology has an important meaning for ensuring the clinical curative effect of traditional Chinese medicine. The provided decoction piece can generate prominent social benefits and economic benefits.

Description

A kind of Flos Paulowniae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof

Technical field

The invention belongs to Chinese crude drug manufacture field, particularly relate to the processing technique of Traditional medicine bubble Flos paulowniae decoction pieces.

Background technology

Traditional medicine bubble Flos paulowniae is goatweed Paulownia paulowniatomentosa(Thunb.) flower of Steud..This product bitter in the mouth is cold in nature, has effect of heat-clearing and toxic substances removing, is mainly used in cough due to lung-heat, bacillary dysentery, the treatment of bronchitis etc.

The processing mode of conventional Flos Paulowniae decoction pieces is: summer, the flowers are in blossom gathers when putting, dry, then accumulating of packing.This type of decoction pieces, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, and quality is difficult to ensure, is unfavorable for that formula is adjusted and guarantees its clinical efficacy, even brings recessive harm to patient.

At present, granule pieces market also having Flos Paulowniae medical material to make after extracting is sold.The preparation process of granule pieces, extracts not only time consumption and energy consumption, and does solvent because commonly using a large amount of water, and the nonpolar effective ingredient in medical material is difficult to be extracted.In addition, because the Flos Paulowniae medical material extracted also is dry also through long-time storage, therefore, the loss of effective ingredient is also very large.In order to ensure clinical effective, the steady quality of Flos Paulowniae medical material, a kind of novel Flos Paulowniae decoction pieces and preparation technology thereof urgently develop.

Summary of the invention

The present invention discloses " a kind of Flos Paulowniae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof ".This technique can retain polarity in Flos Paulowniae medical material and nonpolar effective ingredient to greatest extent, the loss of effective ingredient avoiding medical material to cause in existing decoction pieces processing and storage and transport process and the decline of medical material quanlity, reduce the pollution of medical material by mycete etc., the steady quality and clinical safety guaranteeing Flos Paulowniae decoction pieces is effectively had great importance.

To achieve these goals, technical scheme of the present invention is:

After Flos Paulowniae is gathered, clean, washing, take advantage of fresh squeezing, medicinal residues add the water of 1 ~ 5 times amount, and stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, and merge three medicine juice, 40 ~ 120 mesh screen, obtain Flos Paulowniae medicine juice.The Flos Paulowniae medicine juice obtained is evaporated to the extractum that relative density is 1.05 ~ 1.25 under 40 ~ 75 DEG C of conditions, and this extractum is freezed 6 ~ 24 hours in-20 ~-80 DEG C of refrigerators, lyophilization again, pressure is 0.06 ~ 0.09MPa, and temperature is-15 ~-40 DEG C, and cooling time is 12 ~ 48 hours, after collecting lyophilized products, through pulverizing, sieving, packing.

On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, decoction pieces manufacturer, date of manufacture, Contents of Main Components, meridian distribution of property and flavor, function cure mainly, the information such as usage and dosage, toxic and side effects and contraindication.TLC distinguish collection of illustrative plates and/or the high-efficient liquid phase character collection of illustrative plates of Flos Paulowniae is enclosed, as " identity card " of product in bag.In addition, in the packaging bag of product, be printed on Quick Response Code, the information such as former plant photo, medical material photo, decoction pieces photo, character and the microscopical identification feature obtaining product can be linked by scanning.

Usefulness of the present invention is:

The Flos Paulowniae medical material of fresh collection, direct squeezing, filtration, concentrating under reduced pressure, lyophilization after cleaning washing, the powder decoction pieces obtained, can retain the effective ingredient in medical material to greatest extent.This decoction pieces volume compares to traditional decoction pieces volume and reduces widely, and vacuum packaging, makes prepared slice quality more stable, is beneficial to accumulating and clinical adjustment, has very significant social meaning and economic implications.

Detailed description of the invention

Embodiment 1

By the Flos Paulowniae medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice.Gained medicinal residues add the tap water of 3 times amount, stir 20min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned 3 medicine juice are merged, filters with 100 eye mesh screens.Filtrate reduced in volume, temperature is set as 65 DEG C.When concentrated gained extractum relative density is 1.15, extractum is freezed 6 hours in-80 DEG C of refrigerators.Take out east knot thing, lyophilization, pressure is 0.09Mpa, and temperature is-20 DEG C, dry 24 hours.Take out lyophilized products, pulverize at low temperature, cross 80 mesh sieves, moisture is not higher than 12%, and pack, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.

Embodiment 2

By the Flos Paulowniae medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice.Gained medicinal residues add the tap water of 5 times amount, stir 30min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned 3 medicine juice are merged, filters with 80 eye mesh screens.Filtrate reduced in volume, temperature is set as 70 DEG C.When concentrated gained extractum relative density is 1.10, extractum is freezed 8 hours in-80 DEG C of refrigerators.Take out east knot thing, lyophilization, pressure is 0.08Mpa, and temperature is-40 DEG C, dry 48 hours.Take out lyophilized products, pulverize at low temperature, cross 60 mesh sieves, moisture is not higher than 12%, and pack, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.

Above embodiment, is only the technological thought that this invention is described, can not limit the every technological thought proposed according to the present invention of protection scope of the present invention whereby, any change that technical scheme basis is done, all falls within the scope of protection of the invention.

Claims

1. a Flos Paulowniae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof, it is characterized in that: after Flos Paulowniae is gathered, clean, washing, take advantage of fresh squeezing, medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, merge three medicine juice, 40 ~ 120 mesh screen, obtain Flos Paulowniae medicine juice.

2. a kind of Flos Paulowniae according to claim 1 fresh squeezing lyophilization powder decoction pieces and preparation technology thereof, it is characterized in that: the Flos Paulowniae medicine juice obtained in claim 1 is evaporated to the extractum that relative density is 1.05 ~ 1.25 under 40 ~ 75 DEG C of conditions, and this extractum is freezed 6 ~ 24 hours in-20 ~-80 DEG C of refrigerators, then lyophilization, pressure is 0.06 ~ 0.09MPa, temperature is-15 ~-40 DEG C, cooling time is 12 ~ 48 hours, after collecting lyophilized products, through pulverizing, sieve, pack.