CN105287858A - Freshly-squeezed paulownia flower spray-dried granular decoction piece and preparation technology thereof - Google Patents
Freshly-squeezed paulownia flower spray-dried granular decoction piece and preparation technology thereof Download PDFInfo
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- CN105287858A CN105287858A CN201510807230.3A CN201510807230A CN105287858A CN 105287858 A CN105287858 A CN 105287858A CN 201510807230 A CN201510807230 A CN 201510807230A CN 105287858 A CN105287858 A CN 105287858A
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Abstract
The invention discloses a freshly-squeezed paulownia flower spray-dried granular decoction piece and a preparation technology thereof. The preparation technology comprises the following steps: after the paulownia flowers are harvested, picking qualified paulownia flowers, washing selected paulownia flowers, squeezing the fresh paulownia flowers, filtering the juice, adding water into the residues, filtering, squeezing; merging the juice, carrying out reduced pressured concentration, spray-drying the liquid, collecting the spray-drying product, grinding the collected solids, mixing the grinded solids with primarily-squeezed juice, carrying out granulation, finishing, and packaging the granules into vacuum bags. The provided preparation method maximally preserves the polar and non-polar effective components in paulownia flowers. The decoction piece has good fluidity, and is convenient for transportation, storage, and blending, the quality is controllable, and the curative effect is reliable. The preparation technology has an important meaning for ensuring the clinical curative effect of traditional Chinese medicine. The provided decoction piece can generate prominent social benefits and economic benefits.
Description
Technical field
The invention belongs to Chinese crude drug manufacture field, particularly relate to the processing technique of Traditional medicine bubble Flos paulowniae decoction pieces.
Background technology
Traditional medicine bubble Flos paulowniae is goatweed Paulownia
paulowniatomentosa(Thunb.) flower of Steud..This product bitter in the mouth is cold in nature, has effect of heat-clearing and toxic substances removing, is mainly used in cough due to lung-heat, bacillary dysentery, the treatment of bronchitis etc.
The processing mode of conventional Flos Paulowniae decoction pieces is: summer, the flowers are in blossom gathers when putting, dry, then accumulating of packing.This type of decoction pieces, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, and quality is difficult to ensure, is unfavorable for that formula is adjusted and guarantees its clinical efficacy, even brings recessive harm to patient.
At present, granule pieces market also having Flos Paulowniae medical material to make after extracting is sold.The preparation process of granule pieces, extracts not only time consumption and energy consumption, and does solvent because commonly using a large amount of water, and the nonpolar effective ingredient in medical material is difficult to be extracted.In addition, because the Flos Paulowniae medical material extracted also is dry also through long-time storage, therefore, the loss of effective ingredient is also very large.In order to ensure clinical effective, the steady quality of Flos Paulowniae medical material, a kind of novel Flos Paulowniae decoction pieces and preparation technology thereof urgently develop.
Summary of the invention
The present invention discloses " a kind of Flos Paulowniae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof ".This technique can retain polarity in Flos Paulowniae medical material and nonpolar effective ingredient to greatest extent, the loss of effective ingredient avoiding medical material to cause in existing decoction pieces processing and storage and transport process and the decline of medical material quanlity, reduce the pollution of medical material by mycete etc., the steady quality and clinical safety guaranteeing Flos Paulowniae decoction pieces is effectively had great importance.
To achieve these goals, technical scheme of the present invention is:
After Flos Paulowniae is gathered, clean, washing, take advantage of fresh squeezing, collect and just squeeze medicine juice, the first squeezing medicine juice of retention 0.5% ~ 5% is for subsequent use, and medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, merge remaining first squeezing medicine juice and rear twice squeezing medicine juice, 60 ~ 120 mesh screen, obtain Flos Paulowniae medicine juice.The Flos Paulowniae medicine juice obtained is evaporated to the concentrated solution that relative density is 1.02 ~ 1.15 under 40 ~ 75 DEG C of conditions, and by this concentrated solution spraying dry, intake air temperature is set as 90 ~ 140 DEG C, air outlet temperature is 80 ~ 110 DEG C, collect desciccate, after pulverizing, cross 60 ~ 100 mesh sieves.By above-mentioned Flos Paulowniae spray drying powder, mix with the first squeezing medicine juice retained, prepare soft material, granulation, 50 ~ 80 DEG C of dryings 4 ~ 8 hours, granulate, vacuum packaging.On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, decoction pieces manufacturer, date of manufacture, Contents of Main Components, meridian distribution of property and flavor, function cure mainly, the information such as usage and dosage, toxic and side effects and contraindication.TLC distinguish collection of illustrative plates and/or the high-efficient liquid phase character collection of illustrative plates of Flos Paulowniae is enclosed, as " identity card " of product in bag.In addition, in the packaging bag of product, be printed on Quick Response Code, the information such as former plant photo, medical material photo, decoction pieces photo, character and the microscopical identification feature obtaining product can be linked by scanning.
Usefulness of the present invention is:
The Flos Paulowniae medical material of fresh collection, direct squeezing, filtration, concentrating under reduced pressure, spraying dry, granulation after cleaning washing, the granule pieces obtained, can retain the effective ingredient in medical material to greatest extent.This decoction pieces volume compares to traditional decoction pieces volume and reduces widely, good fluidity, and vacuum packaging, makes prepared slice quality more stable, is beneficial to accumulating and clinical adjustment, has very significant social meaning and economic implications.
Detailed description of the invention
Embodiment 1
By the Flos Paulowniae medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice, the first squeezing medicine juice retaining 1% weight is separately used.Gained medicinal residues add the tap water of 3 times amount, stir 20min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned remaining just squeezing medicine juice and the follow-up medicine juice that squeezes for twice are merged, filters with 100 eye mesh screens.Filtrate reduced in volume, temperature is set as 65 DEG C.When concentrated gained extractum relative density is 1.05, spraying dry, intake air temperature is 140 DEG C, and air outlet temperature is 100 DEG C, collects spray dry, pulverize at low temperature, crosses 80 mesh sieves.This spray drying powder is mixed soft material processed with the first squeezing medicine juice of above-mentioned retention, granulates, 75 DEG C of dryings 6 hours, granulate, pack, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.
Embodiment 2
By the Flos Paulowniae medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice, the first squeezing medicine juice retaining 5% weight is separately used.Gained medicinal residues add the tap water of 5 times amount, stir 30min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned remaining just squeezing medicine juice and the follow-up medicine juice that squeezes for twice are merged, filters with 100 eye mesh screens.Filtrate reduced in volume, temperature is set as 70 DEG C.When concentrated gained extractum relative density is 1.10, spraying dry, intake air temperature is 120 DEG C, and air outlet temperature is 90 DEG C, collects spray dry, pulverize at low temperature, crosses 80 mesh sieves.This spray drying powder is mixed soft material processed with the first squeezing medicine juice of above-mentioned retention, granulates, 70 DEG C of dryings 8 hours, granulate, pack, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.
Above embodiment, is only the technological thought that this invention is described, can not limit the every technological thought proposed according to the present invention of protection scope of the present invention whereby, any change that technical scheme basis is done, all falls within the scope of protection of the invention.
Claims (3)
1. Flos Paulowniae fresh squeezing spray-dried granules decoction pieces and a preparation technology thereof, is characterized in that: after Flos Paulowniae is gathered, clean, washing, takes advantage of fresh squeezing, collects and just squeezes medicine juice, the first squeezing medicine juice of retention 0.5% ~ 5% is for subsequent use, medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, merge remaining first squeezing medicine juice and rear twice squeezing medicine juice, 60 ~ 120 mesh screen, obtain Flos Paulowniae medicine juice.
2. a kind of Flos Paulowniae fresh squeezing spray-dried granules decoction pieces according to claim 1 and preparation technology thereof, it is characterized in that: the Flos Paulowniae medicine juice obtained in claim 1 is evaporated to the concentrated solution that relative density is 1.02 ~ 1.15 under 40 ~ 75 DEG C of conditions, and by this concentrated solution spraying dry, intake air temperature is set as 90 ~ 140 DEG C, air outlet temperature is 80 ~ 110 DEG C, collect desciccate, after pulverizing, cross 60 ~ 100 mesh sieves.
3. a kind of Flos Paulowniae fresh squeezing spray-dried granules decoction pieces according to claim 1 and preparation technology thereof, it is characterized in that: by the Flos Paulowniae spray drying powder in claim 2, mix with the first squeezing medicine juice retained in claim 1, prepare soft material, granulate, 50 ~ 80 DEG C of dryings 4 ~ 8 hours, granulate, vacuum packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510807230.3A CN105287858A (en) | 2015-11-22 | 2015-11-22 | Freshly-squeezed paulownia flower spray-dried granular decoction piece and preparation technology thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510807230.3A CN105287858A (en) | 2015-11-22 | 2015-11-22 | Freshly-squeezed paulownia flower spray-dried granular decoction piece and preparation technology thereof |
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| CN105287858A true CN105287858A (en) | 2016-02-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510807230.3A Pending CN105287858A (en) | 2015-11-22 | 2015-11-22 | Freshly-squeezed paulownia flower spray-dried granular decoction piece and preparation technology thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998168A (en) * | 2016-07-23 | 2016-10-12 | 徐自升 | Spray-dried granular medicinal slices prepared from freshly squeezed flos sophorae and preparation process thereof |
| CN106109530A (en) * | 2016-07-23 | 2016-11-16 | 徐漫 | A kind of Folium Isatidis fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN106109575A (en) * | 2016-07-24 | 2016-11-16 | 徐漫 | A kind of Herba Scutellariae Barbatae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN106109622A (en) * | 2016-07-23 | 2016-11-16 | 徐漫 | A kind of Herba Agrimoniae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN106214723A (en) * | 2016-07-23 | 2016-12-14 | 徐漫 | A kind of Herba Lobeliae Chinensis fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN107213186A (en) * | 2017-06-20 | 2017-09-29 | 徐漫 | A kind of acalypha copperleaf is fresh to squeeze spray-dried granules medicine materical crude slice and its preparation technology |
| CN107233384A (en) * | 2017-06-22 | 2017-10-10 | 徐漫 | A kind of motherwort is fresh to squeeze spray-dried granules medicine materical crude slice and its preparation technology |
| CN107375381A (en) * | 2017-08-25 | 2017-11-24 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of tussilago |
-
2015
- 2015-11-22 CN CN201510807230.3A patent/CN105287858A/en active Pending
Non-Patent Citations (3)
| Title |
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| 南京药学院药剂学教研组: "《药剂学》", 31 May 1962, 人民卫生出版社 * |
| 周思: "《偏方秘方大全》", 31 January 2008, 中国妇女出版社 * |
| 国家食品药品监督管理局执业药师资格认证中心: "《中药学专业知识.1》", 31 January 2014, 中国医药科技出版社 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998168A (en) * | 2016-07-23 | 2016-10-12 | 徐自升 | Spray-dried granular medicinal slices prepared from freshly squeezed flos sophorae and preparation process thereof |
| CN106109530A (en) * | 2016-07-23 | 2016-11-16 | 徐漫 | A kind of Folium Isatidis fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN106109622A (en) * | 2016-07-23 | 2016-11-16 | 徐漫 | A kind of Herba Agrimoniae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN106214723A (en) * | 2016-07-23 | 2016-12-14 | 徐漫 | A kind of Herba Lobeliae Chinensis fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN106109575A (en) * | 2016-07-24 | 2016-11-16 | 徐漫 | A kind of Herba Scutellariae Barbatae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN107213186A (en) * | 2017-06-20 | 2017-09-29 | 徐漫 | A kind of acalypha copperleaf is fresh to squeeze spray-dried granules medicine materical crude slice and its preparation technology |
| CN107233384A (en) * | 2017-06-22 | 2017-10-10 | 徐漫 | A kind of motherwort is fresh to squeeze spray-dried granules medicine materical crude slice and its preparation technology |
| CN107375381A (en) * | 2017-08-25 | 2017-11-24 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of tussilago |
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