CN105213453A

CN105213453A - A kind of Herba Taraxaci fresh squeezing lyophilization powder decoction pieces and preparation technology thereof

Info

Publication number: CN105213453A
Application number: CN201510774368.8A
Authority: CN
Inventors: 黄竹青
Original assignee: Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Current assignee: Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Priority date: 2015-11-14
Filing date: 2015-11-14
Publication date: 2016-01-06

Abstract

The present invention discloses a kind of Herba Taraxaci fresh squeezing lyophilization powder decoction pieces and preparation technology thereof.This technique, after Herba Taraxaci medical material is gathered, to clean, drip washing, and takes advantage of fresh squeezing, leaching medicine juice.Medicinal residues add water stirring again, filter squeezing.Concentrating under reduced pressure after gained medicine juice merges, lyophilization, collects lyophilized products, after crushed vacuum packaging.The Herba Taraxaci powder decoction pieces that this legal system is standby, remains the polarity in medical material and nonpolar effective ingredient to greatest extent.Decoction pieces is beneficial to accumulating, convenient adjustment, and quality controllable, curative effect is reliable, has great importance to guarantee tcm clinical curative effect.The promotion and implementation of this law, will have significant social meaning and economic benefit.

Description

A kind of Herba Taraxaci fresh squeezing lyophilization powder decoction pieces and preparation technology thereof

Technical field

The invention belongs to Chinese crude drug manufacture field, particularly relate to the processing technique of Chinese traditional drug taraxacum herb decoction pieces.

Background technology

Chinese traditional drug taraxacum herb is feverfew Herba Taraxaci taraxacummongolicumhand.-Mazz., alkali ground Herba Taraxaci taraxacumborealisinenseor belong to the dry herb of several plants together Kitam..This product is bitter, sweet, cold.Return liver, stomach warp.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of inducing diuresis for treating stranguria syndrome.Clinical being mainly used in treats furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria etc.

The processing mode of conventional Herba Taraxaci decoction pieces is: spend spring to autumn when just opening and excavate, and removing impurity, cleans, dry, then accumulating of packing.This type of prepared herbal medicine in small pieces ready for decoction, bulky, easily pollute and go mouldy, quality is difficult to ensure, is unfavorable for that formula is adjusted and guarantees its clinical efficacy, even brings recessive harm to patient.

At present, granule pieces market also having Herba Taraxaci medical material to make after extracting is sold.The preparation process of granule pieces, extracts not only time consumption and energy consumption, and does solvent because commonly using a large amount of water, and the nonpolar effective ingredient in medical material is difficult to be extracted.In addition, because the Herba Taraxaci medical material extracted also is dry also through long-time storage, therefore, the loss of effective ingredient is also very large.In order to ensure clinical effective, the steady quality of Herba Taraxaci medical material, a kind of novel Herba Taraxaci decoction pieces and preparation technology thereof urgently develop.

Summary of the invention

The present invention discloses " a kind of Herba Taraxaci fresh squeezing lyophilization powder decoction pieces and preparation technology thereof ".This technique can retain polarity in Herba Taraxaci medical material and nonpolar effective ingredient to greatest extent, the loss of effective ingredient avoiding medical material to cause in existing decoction pieces processing and storage and transport process and the decline of medical material quanlity, reduce the pollution of medical material by mycete etc., the steady quality and clinical safety guaranteeing Herba Taraxaci decoction pieces is effectively had great importance.

To achieve these goals, technical scheme of the present invention is:

Gather its herb collection period at Herba Taraxaci, clean, after washing, take advantage of fresh squeezing, medicinal residues add the water of 1 ~ 5 times amount, and stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, and merge three medicine juice, 40 ~ 120 mesh screen, obtain Herba Taraxaci medicine juice.The Herba Taraxaci medicine juice obtained is evaporated to the extractum that relative density is 1.05 ~ 1.25 under 40 ~ 75 DEG C of conditions, and this extractum is freezed 6 ~ 24 hours in-20 ~-80 DEG C of refrigerators, lyophilization again, pressure is 0.06 ~ 0.09MPa, and temperature is-15 ~-40 DEG C, and cooling time is 12 ~ 48 hours, after collecting lyophilized products, through pulverizing, sieving, packing.

On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, decoction pieces manufacturer, date of manufacture, Contents of Main Components, meridian distribution of property and flavor, function cure mainly, the information such as usage and dosage, toxic and side effects and contraindication.TLC distinguish collection of illustrative plates and/or the high-efficient liquid phase character collection of illustrative plates of Herba Taraxaci is enclosed, as " identity card " of product in bag.In addition, in the packaging bag of product, be printed on Quick Response Code, the information such as former plant photo, medical material photo, decoction pieces photo, character and the microscopical identification feature obtaining product can be linked by scanning.

Usefulness of the present invention is:

The Herba Taraxaci medical material of fresh collection, direct squeezing, filtration, concentrating under reduced pressure, lyophilization after cleaning washing, the powder decoction pieces obtained, can retain the effective ingredient in medical material to greatest extent.This decoction pieces volume compares to traditional decoction pieces volume and reduces widely, and vacuum packaging, makes prepared slice quality more stable, is beneficial to accumulating and clinical adjustment, has very significant social meaning and economic implications.

Detailed description of the invention

Embodiment 1

By the Herba Taraxaci medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice.Gained medicinal residues add the tap water of 3 times amount, stir 20min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned 3 medicine juice are merged, filters with 100 eye mesh screens.Filtrate reduced in volume, temperature is set as 65 DEG C.When concentrated gained extractum relative density is 1.15, extractum is freezed 6 hours in-80 DEG C of refrigerators.Take out east knot thing, lyophilization, pressure is 0.09Mpa, and temperature is-20 DEG C, dry 24 hours.Take out lyophilized products, pulverize at low temperature, cross 80 mesh sieves, moisture is not higher than 12%, and pack, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.

Embodiment 2

By the Herba Taraxaci medical material of fresh collection, clean, wash silt with water, take advantage of using fresh herb squeezer squeezing extracting juice.Gained medicinal residues add the tap water of 5 times amount, stir 30min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned 3 medicine juice are merged, filters with 80 eye mesh screens.Filtrate reduced in volume, temperature is set as 70 DEG C.When concentrated gained extractum relative density is 1.10, extractum is freezed 8 hours in-80 DEG C of refrigerators.Take out east knot thing, lyophilization, pressure is 0.08Mpa, and temperature is-40 DEG C, dry 48 hours.Take out lyophilized products, pulverize at low temperature, cross 60 mesh sieves, moisture is not higher than 12%, and pack, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package, labeling.

Above embodiment, is only the technological thought that this invention is described, can not limit the every technological thought proposed according to the present invention of protection scope of the present invention whereby, any change that technical scheme basis is done, all falls within the scope of protection of the invention.

Claims

1. a Herba Taraxaci fresh squeezing lyophilization powder decoction pieces and preparation technology thereof, it is characterized in that: gather its herb collection period at Herba Taraxaci, clean, after washing, take advantage of fresh squeezing, medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, merge three medicine juice, 40 ~ 120 mesh screen, obtain Herba Taraxaci medicine juice.

2. a kind of Herba Taraxaci according to claim 1 fresh squeezing lyophilization powder decoction pieces and preparation technology thereof, it is characterized in that: the Herba Taraxaci medicine juice obtained is evaporated to the extractum that relative density is 1.05 ~ 1.25 under 40 ~ 75 DEG C of conditions, and this extractum is freezed 6 ~ 24 hours in-20 ~-80 DEG C of refrigerators, then lyophilization, pressure is 0.06 ~ 0.09MPa, temperature is-15 ~-40 DEG C, cooling time is 12 ~ 48 hours, after collecting lyophilized products, through pulverizing, sieve, pack.