CN105213552A - A kind of Herba Hedyotidis Diffusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof - Google Patents
A kind of Herba Hedyotidis Diffusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof Download PDFInfo
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- CN105213552A CN105213552A CN201510774865.8A CN201510774865A CN105213552A CN 105213552 A CN105213552 A CN 105213552A CN 201510774865 A CN201510774865 A CN 201510774865A CN 105213552 A CN105213552 A CN 105213552A
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- herba hedyotidis
- hedyotidis diffusae
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Abstract
The present invention discloses a kind of Herba Hedyotidis Diffusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof.This technique, after Herba Hedyotidis Diffusae medical material is gathered, to clean, drip washing, and takes advantage of fresh squeezing, leaching medicine juice.Medicinal residues add water stirring again, filter squeezing.Concentrating under reduced pressure after gained medicine juice merges, lyophilization, pulverizes final vacuum packaging.The Spreading Hedyotis Herb decoction pieces that this legal system is standby, remains the polarity in medical material and nonpolar effective ingredient to greatest extent.Decoction pieces is beneficial to accumulating, convenient adjustment, and quality controllable, curative effect is reliable, has great importance to guarantee tcm clinical curative effect.The promotion and implementation of this law, will have significant social meaning and economic benefit.
Description
Technical field
The invention belongs to Chinese crude drug manufacture field, particularly relate to the processing technique of Chinese medicine Herba Hedyotidis Diffusae decoction pieces.
Background technology
Chinese medicine Herba Hedyotidis Diffusae is Maguireothamnus speciosus Herba Hedyotidis Diffusae
oldenlandiadiffusa(Willd.) the dry herb of Roxb. is bitter in the mouth, light, cold in nature.This product has effect of heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Can be used for the diseases such as treatment dyspnea and cough due to lung-heat, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, dysentery, enteritis.
The processing mode of conventional Herba Hedyotidis Diffusae decoction pieces is: after herb of gathering, and removing impurity, cleans silt, dry, then accumulating of packing.This type of prepared herbal medicine in small pieces ready for decoction, bulky, easily pollute and go mouldy, quality is difficult to ensure, is unfavorable for that formula is adjusted and guarantees its clinical efficacy, even brings recessive harm to patient.
At present, granule pieces market also having Herba Hedyotidis Diffusae medical material to make after extracting is sold.The preparation process of granule pieces, extracts not only time consumption and energy consumption, and does solvent because commonly using a large amount of water, and the nonpolar effective ingredient in medical material is difficult to be extracted.In addition, because the Herba Hedyotidis Diffusae medical material extracted also is dry also through long-time storage, therefore, the loss of effective ingredient is also very large.In order to ensure clinical effective, the steady quality of Herba Hedyotidis Diffusae medical material, a kind of novel Herba Hedyotidis Diffusae decoction pieces and preparation technology thereof urgently develop.
Summary of the invention
The present invention discloses " a kind of Herba Hedyotidis Diffusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof ".This technique can retain polarity in Herba Hedyotidis Diffusae medical material and nonpolar effective ingredient to greatest extent, the loss of effective ingredient avoiding medical material to cause in existing decoction pieces processing and storage and transport process and the decline of medical material quanlity, reduce the pollution of medical material by mycete etc., the steady quality and clinical safety guaranteeing Herba Hedyotidis Diffusae decoction pieces is effectively had great importance.
To achieve these goals, technical scheme of the present invention is:
Its herb is gathered collection period Herba Hedyotidis Diffusae, clean, after washing, take advantage of the section that fresh-cut becomes 1 ~ 10cm, squeezing, medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, merge three medicine juice, 40 ~ 120 mesh screen, obtain Herba Hedyotidis Diffusae medicine juice.The Herba Hedyotidis Diffusae medicine juice obtained is evaporated to the extractum that relative density is 1.15 ~ 1.25 under 40 ~ 75 DEG C of conditions, and this extractum is put in-20 ~-80 DEG C of refrigerators freeze 6 ~ 24 hours, again in temperature be-15 ~-40 DEG C, pressure is under 0.06 ~ 0.09MPa condition, carries out lyophilization 12 ~ 48 hours, collects lyophilized products, pulverize, cross 60 ~ 120 mesh sieves, vacuum packaging, obtain product.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, decoction pieces manufacturer, date of manufacture, Contents of Main Components, meridian distribution of property and flavor, function cure mainly, the information such as usage and dosage, toxic and side effects and contraindication.TLC distinguish collection of illustrative plates and/or the high-efficient liquid phase character collection of illustrative plates of Herba Hedyotidis Diffusae is enclosed, as " identity card " of product in bag.In addition, in the packaging bag of product, be printed on Quick Response Code, the information such as former plant photo, medical material photo, decoction pieces photo, character and the microscopical identification feature obtaining product can be linked by scanning.
Usefulness of the present invention is:
The Herba Hedyotidis Diffusae medical material of fresh collection, direct squeezing, filtration, concentrating under reduced pressure, lyophilization after cleaning washing, the powder decoction pieces obtained, can retain the effective ingredient in medical material to greatest extent.This decoction pieces volume compares to traditional decoction pieces volume and reduces widely, and vacuum packaging, makes prepared slice quality more stable, is beneficial to accumulating and clinical adjustment, has very significant social meaning and economic implications.
Detailed description of the invention
Embodiment 1
By the Herba Hedyotidis Diffusae medical material of fresh collection, clean, wash silt with water, take advantage of the section that fresh-cut becomes 5cm, squeeze extracting juice with squeezer.Gained medicinal residues add the tap water of 3 times amount, stir 20min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned 3 medicine juice are merged, filters with 100 eye mesh screens.Filtrate reduced in volume, temperature is set as 65 DEG C.When concentrated gained extractum relative density is 1.15, transfers in-20 DEG C of refrigerators and freeze 12 hours.Scars are taken out postlyophilization, and temperature is-20 DEG C, and pressure is 0.09Mpa, and freeze-drying time is 48 hours.Collect lyophilized products, pulverize, subpackage, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package.
Embodiment 2
By the Herba Hedyotidis Diffusae medical material of fresh collection, clean, wash silt with water, take advantage of the section that fresh-cut becomes 10cm, squeeze extracting juice with squeezer.Gained medicinal residues add the tap water of 5 times amount, stir 30min, filter press squeezing extracting juice.Remaining medicinal residues squeeze extracting juice with squeezer again.Above-mentioned 3 medicine juice are merged, filters with 80 eye mesh screens.Filtrate reduced in volume, temperature is set as 70 DEG C.When concentrated gained extractum relative density is 1.10, transfers in-80 DEG C of refrigerators and freeze 8 hours.Scars are taken out postlyophilization, and temperature is-30 DEG C, and pressure is 0.08Mpa, and freeze-drying time is 24 hours.Collect lyophilized products, pulverize, subpackage, 1kg/ bag, adds packed antioxidant and desiccant, Vacuum Package.
Above embodiment, is only the technological thought that this invention is described, can not limit the every technological thought proposed according to the present invention of protection scope of the present invention whereby, any change that technical scheme basis is done, all falls within the scope of protection of the invention.
Claims (2)
1. Herba Hedyotidis Diffusae fresh squeezing lyophilization powder decoction pieces and a preparation technology thereof, is characterized in that: gather its herb collection period Herba Hedyotidis Diffusae, clean, after washing, take advantage of the section that fresh-cut becomes 1 ~ 10cm, squeezing, medicinal residues add the water of 1 ~ 5 times amount, stir 5 ~ 30min, filter press filter pressing extracting juice, remaining medicinal residues squeeze extracting juice again, merge three medicine juice, 40 ~ 120 mesh screen, obtain Herba Hedyotidis Diffusae medicine juice.
2. a kind of Herba Hedyotidis Diffusae according to claim 1 fresh squeezing lyophilization powder decoction pieces and preparation technology thereof, it is characterized in that: the Herba Hedyotidis Diffusae medicine juice obtained in claim 1 is evaporated to the extractum that relative density is 1.15 ~ 1.25 under 40 ~ 75 DEG C of conditions, and this extractum is put in-20 ~-80 DEG C of refrigerators freeze 6 ~ 24 hours, again in temperature be-15 ~-40 DEG C, pressure is under 0.06 ~ 0.09MPa condition, carry out lyophilization 12 ~ 48 hours, collect lyophilized products, pulverize, cross 60 ~ 120 mesh sieves, vacuum packaging, obtains product.
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| CN201510774865.8A CN105213552A (en) | 2015-11-14 | 2015-11-14 | A kind of Herba Hedyotidis Diffusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof |
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Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998395A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Herba Verbenae freshly squeezed freeze drying powder decoction piece and preparation technology thereof |
| CN105998132A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Chinese lobelia freshly-squeezed freeze drying powder decoction tablets and preparation process thereof |
| CN105998130A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Folium Isatidis freshly-pressed lyophilized powdery decoction pieces and preparation process thereof |
| CN106109545A (en) * | 2016-07-24 | 2016-11-16 | 徐漫 | A kind of Herba Euphorbiae Humifusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof |
| CN106214741A (en) * | 2016-07-24 | 2016-12-14 | 徐漫 | A kind of Herba Scutellariae Barbatae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof |
| CN107213187A (en) * | 2017-06-20 | 2017-09-29 | 徐漫 | A kind of acalypha copperleaf is fresh to squeeze freeze-dried powder medicine materical crude slice and its preparation technology |
| CN107233385A (en) * | 2017-06-22 | 2017-10-10 | 徐漫 | A kind of motherwort is fresh to squeeze freeze-dried powder medicine materical crude slice and its preparation technology |
| CN107320582A (en) * | 2017-08-25 | 2017-11-07 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of Chinese violet |
| CN107375556A (en) * | 2017-08-25 | 2017-11-24 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Chinese violet |
| CN107412302A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of eclipta |
| CN107412290A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Chinese trumpet creeper |
| CN107441155A (en) * | 2017-08-25 | 2017-12-08 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of Longtube Ground Ivy Herb |
| CN107441201A (en) * | 2017-08-25 | 2017-12-08 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of loguat leaf |
| CN107485646A (en) * | 2017-08-25 | 2017-12-19 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of mulberry leaf |
| CN107485628A (en) * | 2017-08-25 | 2017-12-19 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of geranium wilfordii |
| CN107485660A (en) * | 2017-08-25 | 2017-12-19 | 芜湖天成普阳中药科技有限公司 | A kind of tangerine leaf is fresh to squeeze freeze-dried powder medicine materical crude slice and its preparation technology |
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| CN1456257A (en) * | 2003-02-20 | 2003-11-19 | 毛友昌 | Fresh motherwort particle preparing method |
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| CN1456257A (en) * | 2003-02-20 | 2003-11-19 | 毛友昌 | Fresh motherwort particle preparing method |
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| 郝近大: "《鲜品中药及其临床应用》", 31 December 1996, 上海科学技术出版社 * |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998395A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Herba Verbenae freshly squeezed freeze drying powder decoction piece and preparation technology thereof |
| CN105998132A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Chinese lobelia freshly-squeezed freeze drying powder decoction tablets and preparation process thereof |
| CN105998130A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Folium Isatidis freshly-pressed lyophilized powdery decoction pieces and preparation process thereof |
| CN106109545A (en) * | 2016-07-24 | 2016-11-16 | 徐漫 | A kind of Herba Euphorbiae Humifusae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof |
| CN106214741A (en) * | 2016-07-24 | 2016-12-14 | 徐漫 | A kind of Herba Scutellariae Barbatae fresh squeezing lyophilization powder decoction pieces and preparation technology thereof |
| CN107213187A (en) * | 2017-06-20 | 2017-09-29 | 徐漫 | A kind of acalypha copperleaf is fresh to squeeze freeze-dried powder medicine materical crude slice and its preparation technology |
| CN107233385A (en) * | 2017-06-22 | 2017-10-10 | 徐漫 | A kind of motherwort is fresh to squeeze freeze-dried powder medicine materical crude slice and its preparation technology |
| CN107320582A (en) * | 2017-08-25 | 2017-11-07 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of Chinese violet |
| CN107375556A (en) * | 2017-08-25 | 2017-11-24 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Chinese violet |
| CN107412302A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of eclipta |
| CN107412290A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Chinese trumpet creeper |
| CN107441155A (en) * | 2017-08-25 | 2017-12-08 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of Longtube Ground Ivy Herb |
| CN107441201A (en) * | 2017-08-25 | 2017-12-08 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of loguat leaf |
| CN107485646A (en) * | 2017-08-25 | 2017-12-19 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of mulberry leaf |
| CN107485628A (en) * | 2017-08-25 | 2017-12-19 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of geranium wilfordii |
| CN107485660A (en) * | 2017-08-25 | 2017-12-19 | 芜湖天成普阳中药科技有限公司 | A kind of tangerine leaf is fresh to squeeze freeze-dried powder medicine materical crude slice and its preparation technology |
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Application publication date: 20160106 |
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