CN107412303A - A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium - Google Patents
A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium Download PDFInfo
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- CN107412303A CN107412303A CN201710739629.1A CN201710739629A CN107412303A CN 107412303 A CN107412303 A CN 107412303A CN 201710739629 A CN201710739629 A CN 201710739629A CN 107412303 A CN107412303 A CN 107412303A
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- Prior art keywords
- eupatorium
- vacuum drying
- concoction
- squeezing
- fresh
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium.The technique is cleaned, eluted, segment after the harvesting of eupatorium medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo；Condensate liquid separation volatile oil is concentrated, and is mixed with vacuum drying thing, sieving pack.Fortune Eupatorium Herb medicine materical crude slice prepared by this method, remains the active ingredient in medicinal material to greatest extent.Medicine materical crude slice is easy to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine eupatorium medicine materical crude slice.
Background technology
Chinese medicine eupatorium is feverfew eupatoriumEupatorium fortunei Turcz. aerial part.This product has virtue
Fragrant stomach invigorating, sweating, the effect of diuresis, it is mainly used in treating summer-heat headache, lossless heating, abdomen uncomfortable in chest is expired, sweet in mouth, halitosis
Deng.
The processing mode of common eupatorium medicine materical crude slice is：Its aerial part is extracted in picking time, shred, dry in the shade or dry into
Medicine；Or it is collated, dry after, packing storage and transport.These dry eupatorium medicinal materials be transported to after prepared slices of Chinese crude drugs factory, it is necessary to
Elution, section, and redry.Existing process time and effort consuming, process repeat, and add the production cost of medicine materical crude slice.In this process
In not only result in it is therein it is water miscible it is a large amount of be lost in, and its abundant volatile effective component also substantial amounts of loss, from
And cause the decline of medical material quanlity and the reduction of clinical efficacy.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily pollute and go mouldy, matter
Amount it is difficult to ensure that, be unfavorable for formula and adjust and ensure its clinical efficacy.
At present, in the market also has the manufactured granule pieces sale after extraction of eupatorium medicinal material.Because prepared by granule pieces
During, extraction not only time consumption and energy consumption, and because conventional water does solvent, the nonpolar active ingredient in medicinal material is difficult to be extracted
Come.Further, since the eupatorium medicinal material of extraction is also to dry and by storage for a long time, therefore, the loss of active ingredient
It is very big.In order to ensure the clinic of eupatorium medicinal material is effective, steady quality, a kind of new eupatorium medicine materical crude slice is urgently developed.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium ".This technique can be maximum
The polarity and the nonpolar active ingredient that retain in eupatorium medicinal material of limit, avoid medicinal material from being processed and storage and transport process in existing medicine materical crude slice
In the loss of caused active ingredient and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, to ensuring eupatorium medicine materical crude slice
Steady quality and clinical safety effectively have great importance.
To achieve these goals, the technical scheme is that：
Its aerial part is gathered in eupatorium picking time, is cleaned, is cut into 1 ~ 2cm section, adds the water of 0.5 ~ 1 times of amount of medicinal material weight,
Stirring 15 ~ 30 minutes, fresh squeezing to be taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice,
The remaining dregs of a decoction add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction, 100 ~ 200 mesh sieve mistakes twice
Filter, obtains eupatorium concoction.By eupatorium concoction, be concentrated under reduced pressure in 40 ~ 65 DEG C, obtain medicinal extract that relative density is 1.05 ~ 1.30 in 40 ~
60 DEG C vacuum drying 4 ~ 8 hours after crush, produce eupatorium it is fresh squeeze vacuum drying powder decoction pieces.
It is the name of an article in printing, medicinal part, planting site, manufacturer, the date of manufacture, main on the label of product packaging bags
The information such as component content, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.The thin layer of eupatorium is enclosed in bag
Differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, two are printed on
Code is tieed up, it is special to link the former plant photo for obtaining product, medicinal material photo, medicine materical crude slice photo, character and microscopical characters by scanning
The information such as sign.
The present invention is advantageous in that：
Directly segment is squeezed, filtered, being concentrated under reduced pressure, being dried in vacuo, separating oil, mixing, institute after fresh eupatorium medicinal material cleans washing
Obtained powder decoction pieces, it can completely retain the active ingredient in medicinal material to greatest extent.This medicine materical crude slice volume is compared to tradition
Medicine materical crude slice volume greatly reduces, and quality is more stable, beneficial to accumulating and clinical adjustment, has very significant social effect and warp
Ji meaning.
Embodiment
Embodiment 1
The eupatorium medicinal material of fresh collection is cleaned, is cut into 1cm section, adds the water of 0.5 times of amount of medicinal material weight, is stirred 15 minutes,
Fresh squeezing is taken advantage of, collects and just squeezes concoction, the dregs of a decoction add the water of 5 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 3 times of amounts
Water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 mesh screens, obtain eupatorium concoction.By eupatorium concoction,
It is concentrated under reduced pressure, temperature is set as 65 DEG C.When medicinal extract relative density obtained by concentration is 1.15, it is transferred in vacuum drying chamber, in
60 DEG C of dryings 6 hours, obtain vacuum drying thing, crushed 60 mesh sieves, get product.
Embodiment 2
The eupatorium medicinal material of fresh collection is cleaned, is cut into 2cm section, adds the water of 1 times of amount of medicinal material weight, stirs 30 minutes, takes advantage of
Fresh squeezing, collect and just squeeze concoction, the dregs of a decoction add the water of 4 times of amounts, stir 10min, press extracting juice, and the remaining dregs of a decoction add 3 times of amounts
Water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain eupatorium concoction.By eupatorium concoction,
It is concentrated under reduced pressure, temperature is set as 65 DEG C.When medicinal extract relative density obtained by concentration is 1.15, it is transferred in vacuum drying chamber, in
60 DEG C of dryings 6 hours, obtain vacuum drying thing, crushed 60 mesh sieves, get product.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
- A kind of 1. fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium, it is characterised in that：Its ground is gathered in eupatorium picking time Upper part, clean, be cut into 1 ~ 2cm section, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 minutes, take advantage of fresh squeezing, receive Collection just squeeze concoction, the dregs of a decoction add 1 ~ 5 times amount water, stir 5 ~ 30min, press extracting juice, the remaining dregs of a decoction add 1 ~ 5 times amount Water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain eupatorium concoction.
- A kind of 2. fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium according to claim 1, it is characterised in that：Will The eupatorium concoction of gained in claim 1,40 ~ 65 DEG C are concentrated under reduced pressure, the medicinal extract that gained relative density is 1.05 ~ 1.30 in 40 ~ 60 DEG C vacuum drying 4 ~ 8 hours after crush, produce eupatorium it is fresh squeeze vacuum drying powder decoction pieces.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710739629.1A CN107412303A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710739629.1A CN107412303A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107412303A true CN107412303A (en) | 2017-12-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710739629.1A Pending CN107412303A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
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| CN (1) | CN107412303A (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524569A (en) * | 2018-07-06 | 2018-09-14 | 徐漫 | Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces |
| CN108619267A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | The coptis is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619235A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Radix scutellariae is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619226A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619357A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Chinese yam is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619231A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Radix Salviae Miltiorrhizae is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619255A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Rheum officinale is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619430A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Smilax is fresh to carry vacuum drying powder decoction pieces |
| CN108635417A (en) * | 2018-07-06 | 2018-10-12 | 徐漫 | The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces |
| CN108671196A (en) * | 2018-07-06 | 2018-10-19 | 徐漫 | Radix Curcumae is fresh to carry spray-dried granules medicine materical crude slice |
| CN108671152A (en) * | 2018-07-06 | 2018-10-19 | 徐漫 | Rhizoma Gastrodiae is fresh to carry spray-dried powders medicine materical crude slice |
Citations (5)
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| CN105213551A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN105213740A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213445A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Portulacae fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105287859A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower freeze-dried powdery decoction piece and preparation technology thereof |
| CN105520986A (en) * | 2016-02-11 | 2016-04-27 | 徐自升 | Folium artemisiae argyi fresh juice spray-dried decoction powder and preparation process thereof |
-
2017
- 2017-08-25 CN CN201710739629.1A patent/CN107412303A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213551A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN105213740A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213445A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Portulacae fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105287859A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower freeze-dried powdery decoction piece and preparation technology thereof |
| CN105520986A (en) * | 2016-02-11 | 2016-04-27 | 徐自升 | Folium artemisiae argyi fresh juice spray-dried decoction powder and preparation process thereof |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524569A (en) * | 2018-07-06 | 2018-09-14 | 徐漫 | Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces |
| CN108619267A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | The coptis is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619235A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Radix scutellariae is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619226A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619357A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Chinese yam is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619231A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Radix Salviae Miltiorrhizae is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619255A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Rheum officinale is fresh to carry spray-dried powders medicine materical crude slice |
| CN108619430A (en) * | 2018-07-06 | 2018-10-09 | 徐漫 | Smilax is fresh to carry vacuum drying powder decoction pieces |
| CN108635417A (en) * | 2018-07-06 | 2018-10-12 | 徐漫 | The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces |
| CN108671196A (en) * | 2018-07-06 | 2018-10-19 | 徐漫 | Radix Curcumae is fresh to carry spray-dried granules medicine materical crude slice |
| CN108671152A (en) * | 2018-07-06 | 2018-10-19 | 徐漫 | Rhizoma Gastrodiae is fresh to carry spray-dried powders medicine materical crude slice |
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| Date | Code | Title | Description |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171201 |
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| WD01 | Invention patent application deemed withdrawn after publication |