CN108524569A - Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces - Google Patents
Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces Download PDFInfo
- Publication number
- CN108524569A CN108524569A CN201810733378.0A CN201810733378A CN108524569A CN 108524569 A CN108524569 A CN 108524569A CN 201810733378 A CN201810733378 A CN 201810733378A CN 108524569 A CN108524569 A CN 108524569A
- Authority
- CN
- China
- Prior art keywords
- decoction
- radix notoginseng
- fresh
- water
- vacuum drying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a kind of " Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:Radix Notoginseng harvest after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, after extracting solution is condensed into clear cream, then be dried under vacuum to water content be less than 10%, crush, be sieved after be vacuum-packed.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of notoginseng decoction piece.
Background technology
Chinese medicine Radix Notoginseng is panax araliaceae plantPanax notoginseng(Burk.)The dry root and root of F.H.Chen
Stem.Excavation before autumn, the flowers are in blossom, has the effect of dissipate stasis of blood hemostasis, detumescence ding-tong.It is mainly used for spitting blood, spits blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, collapsed
Leakage, traumatic hemorrhage, chest and abdomen shouting pain, the treatment of tumbling and swelling etc. are a herbs common on tcm clinical practice.Traditional Radix Notoginseng adds
Work method is:It after medicinal material is excavated, cleans, separates main root, branch root and rhizome, it is dry, it is packaged, storage and transportation.To after medicine materical crude slice factory, then wash
It washs, soften, be sliced, dry, pack.Such medicine materical crude slice volume is big, and Hygienic Standard is poor, is easy to make moist, mildew, is unfavorable for taking care of,
Storage and transportation cost are high.In addition, such notoginseng decoction piece quality stability is poor, clinical efficacy is difficult to ensure, patient takes not
It is convenient, it works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping, carry and user
Just, rapid-action novel notoginseng decoction piece, it is imperative.Notoginseng decoction piece currently on the market is also super other than traditional medicine materical crude slice
Two kinds of forms of micro mist medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality is decided by traditional drink
The quality of piece, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;Concentrated granular can only extract water soluble ingredient.
Invention content
The invention discloses a kind of " Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:It is harvested in Radix Notoginseng
Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm
Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine
Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.15 ~ 1.25 clear cream.The clear cream of gained is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, is crushed, 60 mesh sieve is crossed,
Vacuum packaging is to get finished product.Finished product medicine materical crude slice contains ginsenoside Rg1(C42H72O14), ginsenoside Rb1(C54H92O23)And Radix Notoginseng soap
Glycosides R1(C47H80O18)Total amount be no less than 6.0%.The clinical general usage amount of this notoginseng decoction piece is 1 ~ 5g, can both enter decoction decoction,
It takes after mixing it with water, also can directly enter in pill, powder, capsule and tablet, to substantially increase the convenience of Clinical practice and comply with
Property, be conducive to the treatment of clinical acute disease.
The present invention solve traditional notoginseng decoction piece is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend
The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular
Piece is more preferable.
Specific embodiment
It after pseudo-ginseng is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure
Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear
Cream.It is 8% that the clear cream of gained is dried under vacuum to water content at 80 DEG C, is crushed, and crosses 60 mesh sieve, is vacuum-packed to get finished product.
Finished product medicine materical crude slice contains ginsenoside Rg1(C42H72O14), ginsenoside Rb1(C54H92O23)And notoginsenoside R(C47H80O18)It is total
Amount is 7.0%.
Claims (2)
1. a kind of Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:It after Radix Notoginseng harvests, cleans, removes in time
The impurity such as silt and dis-medicinal part are added 1 ~ 5 times in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness
The water that 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice;5 ~ 10 are added in the gained dregs of a decoction
The water of times weight, boils 10 ~ 30 minutes, filters while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;Merge above-mentioned concoction, crosses 60 ~ 100
Mesh sieves, and is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, is concentrated into the clear cream that relative density is 1.15 ~ 1.25;By the clear cream of gained 60 ~
It is dried under vacuum to water content at 80 DEG C and is less than 10%, crushes, crosses 60 mesh sieve, is vacuum-packed to get finished product;Finished product medicine materical crude slice contains ginseng
Saponin(e Rg1(C42H72O14), ginsenoside Rb1(C54H92O23)And notoginsenoside R(C47H80O18)Total amount be no less than 6.0%.
2. Radix Notoginseng according to claim 1 is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:Clinic generally uses
Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
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CN201810733378.0A CN108524569A (en) | 2018-07-06 | 2018-07-06 | Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces |
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CN201810733378.0A CN108524569A (en) | 2018-07-06 | 2018-07-06 | Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110624645A (en) * | 2018-09-21 | 2019-12-31 | 云南崔三七药业股份有限公司 | Preparation process of notoginsenoside |
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CN107362182A (en) * | 2017-08-25 | 2017-11-21 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of phoenix-tail fern |
CN107412303A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
CN107432883A (en) * | 2017-08-25 | 2017-12-05 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed |
CN107582624A (en) * | 2017-08-25 | 2018-01-16 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin |
CN108186690A (en) * | 2018-03-21 | 2018-06-22 | 山西省医药与生命科学研究院 | A kind of Chinese medicine processing method |
-
2018
- 2018-07-06 CN CN201810733378.0A patent/CN108524569A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107362182A (en) * | 2017-08-25 | 2017-11-21 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of phoenix-tail fern |
CN107412303A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
CN107432883A (en) * | 2017-08-25 | 2017-12-05 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed |
CN107582624A (en) * | 2017-08-25 | 2018-01-16 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin |
CN108186690A (en) * | 2018-03-21 | 2018-06-22 | 山西省医药与生命科学研究院 | A kind of Chinese medicine processing method |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110624645A (en) * | 2018-09-21 | 2019-12-31 | 云南崔三七药业股份有限公司 | Preparation process of notoginsenoside |
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Application publication date: 20180914 |