CN108619194A - American ginseng fresh carries freeze-dried powder medicine materical crude slice - Google Patents
American ginseng fresh carries freeze-dried powder medicine materical crude slice Download PDFInfo
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- CN108619194A CN108619194A CN201810733219.0A CN201810733219A CN108619194A CN 108619194 A CN108619194 A CN 108619194A CN 201810733219 A CN201810733219 A CN 201810733219A CN 108619194 A CN108619194 A CN 108619194A
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- Prior art keywords
- freeze
- american ginseng
- materical crude
- crude slice
- decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of " American ginseng fresh carry freeze-dried powder medicine materical crude slice ", are primarily characterized in that：American Ginseng harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution is freeze-dried after being condensed into clear cream, then is vacuum-packed after crushing, being sieved.The water content of powder decoction pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of American Ginseng medicine materical crude slice.
Background technology
Traditional Chinese medicine American ginseng is Araliaceae American GinsengPanax quinquefoliumL. dry root.This product, which has, mends
Gas yin-nourishing, clearing heat and promoting fluid.Clinic is usually used in deficiency of vital energy yin deficiency, and abnormal heat is tired of that tired, cough and asthma phlegm blood, Heat Diabetes, dryness of the mouth and throat etc. are controlled
It treats.The processing method of traditional American Ginseng is：It after medicinal material is excavated, cleans, dry or low temperature dry, is packaged, storage and transportation.To medicine materical crude slice factory
Afterwards, it then washs, soften, be sliced, dry, pack.Such medicine materical crude slice volume is big, and Hygienic Standard is poor, is easy to make moist, is mildew, infested,
It is unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, clinical efficacy is difficult to ensure, patient
Inconvenience is taken, is worked slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, conducive to keeping, carry and make
It is imperative with convenient, rapid-action novel American Ginseng medicine materical crude slice.Existing market American Ginseng medicine materical crude slice, other than traditional medicine materical crude slice, also
There are two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality is decided by pass
The quality of system medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only extract water soluble ingredient.
Invention content
The invention discloses a kind of " American ginseng fresh carry freeze-dried powder medicine materical crude slice ", are primarily characterized in that：In American Ginseng
After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~
The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering,
Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.15 ~ 1.25 clear cream.It is cold in -20 ~ -40 DEG C of vacuum after gained clear cream is freezed 12 ~ 24 hours in -20 ~ -80 DEG C of refrigerators
It is lyophilized dry.Lyophilized products be dried under vacuum to again at 60 ~ 80 DEG C water content be less than 10%, crush, cross 60 mesh sieve, vacuum packaging to get at
Product.Total amount of the finished product containing ginsenoside Rg1, ginsenoside Re and ginsenoside Rb1 is no less than 4.0%.
The clinical general usage amount of this medicine materical crude slice is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter pill, powder, glue
In wafer and tablet, to substantially increase the convenience and compliance of Clinical practice, be conducive to the treatment of clinical acute disease.
The present invention solve traditional American Ginseng medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested,
The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular
Medicine materical crude slice is more preferable.
Specific embodiment
It after American ginseng medicine is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction
Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.20 to be concentrated into relative density
Clear cream.By the clear cream of gained after -80 DEG C are freezed 12 hours, in -40 DEG C of vacuum freeze dryings.Dried object is dry with 60 DEG C of vacuum again
It is dry to water content be 8%, crush, cross 60 mesh sieve, be vacuum-packed to get finished product.Finished product containing ginsenoside Rg1, ginsenoside Re and
The total amount of ginsenoside Rb1 is 4.5%.
Claims (2)
1. a kind of American ginseng fresh carries freeze-dried powder medicine materical crude slice, it is primarily characterized in that：It is net in time after American ginseng medicine harvesting
Choosing, removal impurity and the dis-medicinal part such as silt, keeps medicinal material surface wettability, cleans and cuts in taking advantage of using fresh herb tap water in 24 hours
At the piece of 2 ~ 5mm thickness, the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight is added, impregnate and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes
Juice；The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects medicine
Juice；Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and it is 1.15 ~ 1.25 to be concentrated into relative density
Clear cream；After gained clear cream freezes 12 ~ 24 hours in -20 ~ -80 DEG C of refrigerators, in -20 ~ -40 DEG C of vacuum freeze dryings；Freeze-drying
Object is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 12% again, crushes, and crosses 60 mesh sieve, is vacuum-packed to get finished product；Finished product contains people
Ginseng saponin(e Rg1, ginsenoside Re and the total amount of ginsenoside Rb1 are no less than 4.0%.
2. American ginseng fresh according to claim 1 carries freeze-dried powder medicine materical crude slice, it is primarily characterized in that：Clinic generally makes
Dosage is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810733219.0A CN108619194A (en) | 2018-07-06 | 2018-07-06 | American ginseng fresh carries freeze-dried powder medicine materical crude slice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810733219.0A CN108619194A (en) | 2018-07-06 | 2018-07-06 | American ginseng fresh carries freeze-dried powder medicine materical crude slice |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108619194A true CN108619194A (en) | 2018-10-09 |
Family
ID=63689681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810733219.0A Withdrawn CN108619194A (en) | 2018-07-06 | 2018-07-06 | American ginseng fresh carries freeze-dried powder medicine materical crude slice |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108619194A (en) |
-
2018
- 2018-07-06 CN CN201810733219.0A patent/CN108619194A/en not_active Withdrawn
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181009 |