CN108524582A

CN108524582A - Campanulaceae is fresh to carry freeze-dried powder medicine materical crude slice

Info

Publication number: CN108524582A
Application number: CN201810733229.4A
Authority: CN
Inventors: 徐璐
Original assignee: Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Current assignee: Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-09-14

Abstract

The invention discloses a kind of " campanulaceae is fresh to carry freeze-dried powder medicine materical crude slice ", are primarily characterized in that：Campanulaceae harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution is freeze-dried after being condensed into clear cream, then is vacuum-packed after crushing, being sieved.The water content of powder decoction pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.

Description

Campanulaceae is fresh to carry freeze-dried powder medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of campanulaceae medicine materical crude slice.

Background technology

Platycodon grandiflorum is the dry root of Campanulaceae campanulaceae, has the effect of facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis.It is main to use In coughing with a lot of sputum, chest distress, pharyngalgia hoarse voice, the treatment of lung carbuncle pyemesis etc. is a herb common on tcm clinical practice.Tradition The processing method of campanulaceae is：Spring, the excavation of two season of autumn, clean, remove fibrous root, take advantage of it is fresh peel off crust or do not remove crust, it is dry, beat Packet, storage and transportation.To after medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice volume is big, and Hygienic Standard is poor, easily In make moist, it is mildew, infested, be unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, it is clinical Curative effect is difficult to ensure, patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, It is imperative conducive to keeping, carrying and easy to use, rapid-action novel campanulaceae medicine materical crude slice.Existing market campanulaceae medicine materical crude slice, in addition to passing It unites except medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, Quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only extract Water soluble ingredient.

Invention content

The invention discloses a kind of " campanulaceae is fresh to carry freeze-dried powder medicine materical crude slice ", are primarily characterized in that：It is harvested in campanulaceae Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.15 ~ 1.25 clear cream.It is cold in -20 ~ -40 DEG C of vacuum after gained clear cream is freezed 12 ~ 24 hours in -20 ~ -80 DEG C of refrigerators It is lyophilized dry.Lyophilized products be dried under vacuum to again at 60 ~ 80 DEG C water content be less than 10%, crush, cross 60 mesh sieve, vacuum packaging to get at Product.Finished product medicine materical crude slice (C containing Platycodin D₅₇H₉₂O₂₈) 0.20% must not be less than.The clinical general usage amount of this medicine materical crude slice is 1 ~ 5g, both may be used Enter decoction decoction, take after mixing it with water, also can directly enter in pill, powder, capsule and tablet, to substantially increase Clinical practice just Victory and compliance are conducive to the treatment of clinical acute disease.

The present invention solve traditional campanulaceae medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.

Specific embodiment

It after campanulaceae medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear Cream.By the clear cream of gained after -80 DEG C are freezed 12 hours, in -40 DEG C of vacuum freeze dryings.Dried object is dried in vacuo with 60 DEG C again It is 8% to water content, crushes, crosses 60 mesh sieve, be vacuum-packed to get finished product.Finished product medicine materical crude slice Platycodin D (C₅₇H₉₂O₂₈) content It is 0.30%.

Claims

1. a kind of campanulaceae is fresh to carry freeze-dried powder medicine materical crude slice, it is primarily characterized in that：After the harvesting of campanulaceae medicinal material, clean in time, Impurity and the dis-medicinal part such as silt are removed, medicinal material surface wettability is kept, cleans in taking advantage of using fresh herb tap water in 24 hours and is cut into 2 The water of 1 ~ 5 times of 50 ~ 70 DEG C of weight is added in the piece of ~ 5mm thickness, impregnates and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes juice； The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction； Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and it is 1.15 ~ 1.25 to be concentrated into relative density Clear cream；After gained clear cream freezes 12 ~ 24 hours in -20 ~ -80 DEG C of refrigerators, in -20 ~ -40 DEG C of vacuum freeze dryings；Lyophilized products Water content is dried under vacuum at 60 ~ 80 DEG C again and is less than 12%, is crushed, 60 mesh sieve is crossed, is vacuum-packed to get finished product；Finished product medicine materical crude slice contains Platycodin D (C₅₇H₉₂O₂₈) 0.20% must not be less than.

2. campanulaceae according to claim 1 is fresh to carry freeze-dried powder medicine materical crude slice, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.