CN108635385A - Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice - Google Patents
Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice Download PDFInfo
- Publication number
- CN108635385A CN108635385A CN201810733239.8A CN201810733239A CN108635385A CN 108635385 A CN108635385 A CN 108635385A CN 201810733239 A CN201810733239 A CN 201810733239A CN 108635385 A CN108635385 A CN 108635385A
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- CN
- China
- Prior art keywords
- radix angelicae
- angelicae sinensis
- fresh
- materical crude
- medicine materical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of " Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice ", are primarily characterized in that:Radix Angelicae Sinensis harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution is freeze-dried after being condensed into clear cream, then is vacuum-packed after crushing, being sieved.The water content of powder decoction pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of angelica sinensis.
Background technology
Chinese traditional medicine angelica is umbelliferae angelicaAngelica sinensis (Oliv.) dry root of Diels..Tradition
The processing method of Radix Angelicae Sinensis is:Autumn end excavates, and removes fibrous root and silt is bundled into wisp after moisture slightly evaporates, upper canopy uses pyrotechnics
Slowly smoke-dried beancurd, then bundle and package, storage and transportation.To after medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice volume
Greatly, Hygienic Standard is poor, is easy to make moist, is mildew, infested, being unfavorable for taking care of, storage and transportation cost are high.In addition, such drink
Tablet quality stability is poor, and clinical efficacy is difficult to ensure, patient takes inconvenience, works slow.Therefore, developing a kind of stable quality can
Lean on, storage/transportation is at low cost, conducive to keeping, carry and easy to use, rapid-action novel radix angelicae sinensis medicine materical crude slice, it is imperative.At present
Market angelica sinensis, other than traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both
Using traditional medicine materical crude slice as raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;
Concentrated granular can only extract water soluble ingredient.
Invention content
The invention discloses a kind of " Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice ", are primarily characterized in that:It is harvested in Radix Angelicae Sinensis
Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm
Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine
Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.15 ~ 1.25 clear cream.It is cold in -20 ~ -40 DEG C of vacuum after gained clear cream is freezed 12 ~ 24 hours in -20 ~ -80 DEG C of refrigerators
It is lyophilized dry.Lyophilized products be dried under vacuum to again at 60 ~ 80 DEG C water content be less than 10%, crush, cross 60 mesh sieve, vacuum packaging to get at
Product.Finished product medicine materical crude slice (C containing ferulic acid10H10O4) 0.070% must not be less than.The clinical general usage amount of this medicine materical crude slice is 1 ~ 5g, can both be entered
Decoction decoction is taken after mixing it with water, and also can directly be entered in pill, powder, capsule and tablet, to substantially increase the convenient of Clinical practice
Property and compliance, are conducive to the treatment of clinical acute disease.
The present invention solve traditional angelica sinensis is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend
The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular
Piece is more preferable.
Specific embodiment
It after Radix Angelicae Sinensis medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure
Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear
Cream.By the clear cream of gained after -80 DEG C are freezed 12 hours, in -40 DEG C of vacuum freeze dryings.Dried object is dried in vacuo with 60 DEG C again
It is 8% to water content, crushes, crosses 60 mesh sieve, be vacuum-packed to get finished product.Finished product medicine materical crude slice (C containing ferulic acid10H10O4) must not be less than
0.075%.
Claims (2)
1. a kind of Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice, it is primarily characterized in that:After the harvesting of Radix Angelicae Sinensis medicinal material, clean in time,
Impurity and the dis-medicinal part such as silt are removed, medicinal material surface wettability is kept, cleans in taking advantage of using fresh herb tap water in 24 hours and is cut into 2
The water of 1 ~ 5 times of 50 ~ 70 DEG C of weight is added in the piece of ~ 5mm thickness, impregnates and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes juice;
The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;
Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and it is 1.15 ~ 1.25 to be concentrated into relative density
Clear cream;After gained clear cream freezes 12 ~ 24 hours in -20 ~ -80 DEG C of refrigerators, in -20 ~ -40 DEG C of vacuum freeze dryings;Lyophilized products
Water content is dried under vacuum at 60 ~ 80 DEG C again and is less than 10%, is crushed, 60 mesh sieve is crossed, is vacuum-packed to get finished product;Finished product medicine materical crude slice contains
Ferulic acid (C10H10O4) 0.070% must not be less than.
2. Radix Angelicae Sinensis according to claim 1 is fresh to carry freeze-dried powder medicine materical crude slice, it is primarily characterized in that:Clinic generally uses
Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733239.8A CN108635385A (en) | 2018-07-06 | 2018-07-06 | Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733239.8A CN108635385A (en) | 2018-07-06 | 2018-07-06 | Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108635385A true CN108635385A (en) | 2018-10-12 |
Family
ID=63750479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810733239.8A Withdrawn CN108635385A (en) | 2018-07-06 | 2018-07-06 | Radix Angelicae Sinensis is fresh to carry freeze-dried powder medicine materical crude slice |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108635385A (en) |
-
2018
- 2018-07-06 CN CN201810733239.8A patent/CN108635385A/en not_active Withdrawn
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181012 |
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WW01 | Invention patent application withdrawn after publication |