CN108671069A - Glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces - Google Patents
Glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces Download PDFInfo
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- CN108671069A CN108671069A CN201810733396.9A CN201810733396A CN108671069A CN 108671069 A CN108671069 A CN 108671069A CN 201810733396 A CN201810733396 A CN 201810733396A CN 108671069 A CN108671069 A CN 108671069A
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- China
- Prior art keywords
- decoction
- fresh
- glutinous rehmannia
- water
- vacuum drying
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of " glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:Glutinous rehmannia harvest after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, after extracting solution is condensed into clear cream, then be dried under vacuum to water content be less than 10%, crush, be sieved after be vacuum-packed.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of radix rehmanniae.
Background technology
Chinese medicine glutinous rehmannia is the fresh or dried root of scrophulariaceae rehmannia glutinosa plant.Glutinous rehmannia has clearing heat and cooling blood, nourishing Yin and promoting production of body fluid
Effect.This product is mainly used for treatment heat and enters ying blood, febrile virulent maculae, hematemesis and epistaxis, consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, Tianjin hinder constipation, the moon
It shoots without hitting the target heat, hectic fever due to yin labor heat, Heat Diabetes etc. is a herb common on tcm clinical practice.The processing method of traditional glutinous rehmannia is:Autumn
Season excavates, and removes removing LU, fibrous root and silt, using fresh herb;Or glutinous rehmannia is slowly baked to about most probably dry, packing, storage and transportation.To medicine materical crude slice factory
Afterwards, it then washs, soften, be sliced, dry, pack.Such medicine materical crude slice volume is big, and Hygienic Standard is poor, is easy to make moist, is mildew, infested,
It is unfavorable for taking care of, storage and transportation cost are high.In addition, such radix rehmanniae quality stability is poor, clinical efficacy is difficult to ensure,
Patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping, carry
It is imperative with easy to use, rapid-action novel radix rehmanniae.Radix rehmanniae currently on the market, in addition to traditional medicine materical crude slice it
Outside, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality determines
In the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;Concentrated granular can only extract it is water-soluble at
Point.
Invention content
The invention discloses a kind of " glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:It is harvested in glutinous rehmannia
Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm
Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine
Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.15 ~ 1.25 clear cream.The clear cream of gained is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, is crushed, 60 mesh sieve is crossed,
Vacuum packaging is to get finished product.Finished product medicine materical crude slice must not be less than 0.040% containing acteoside.This radix rehmanniae clinic generally uses
Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet, to greatly improve
The convenience and compliance of Clinical practice, is conducive to the treatment of clinical acute disease.
The present invention solve traditional radix rehmanniae is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend
The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular
Piece is more preferable.
Specific embodiment
It after glutinous rehmannia medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure
Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear
Cream.It is 8% that the clear cream of gained is dried under vacuum to water content at 80 DEG C, is crushed, and crosses 60 mesh sieve, is vacuum-packed to get finished product.
The content of acteoside is 0.050% in finished product medicine materical crude slice.
Claims (2)
1. a kind of glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:It after glutinous rehmannia harvests, cleans, removes in time
The impurity such as silt and dis-medicinal part are added 1 ~ 5 times in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness
The water that 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice;5 ~ 10 are added in the gained dregs of a decoction
The water of times weight, boils 10 ~ 30 minutes, filters while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;Merge above-mentioned concoction, crosses 60 ~ 100
Mesh sieves, and is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, is concentrated into the clear cream that relative density is 1.15 ~ 1.25;By the clear cream of gained 60 ~
It is dried under vacuum to water content at 80 DEG C and is less than 10%, crushes, crosses 60 mesh sieve, is vacuum-packed to get finished product;Finished product medicine materical crude slice stamen containing hair
Flower glucosides must not be less than 0.040%.
2. glutinous rehmannia according to claim 1 is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:Clinic generally uses
Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733396.9A CN108671069A (en) | 2018-07-06 | 2018-07-06 | Glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733396.9A CN108671069A (en) | 2018-07-06 | 2018-07-06 | Glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108671069A true CN108671069A (en) | 2018-10-19 |
Family
ID=63813498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201810733396.9A Withdrawn CN108671069A (en) | 2018-07-06 | 2018-07-06 | Glutinous rehmannia is fresh to carry vacuum drying powder decoction pieces |
Country Status (1)
Country | Link |
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CN (1) | CN108671069A (en) |
-
2018
- 2018-07-06 CN CN201810733396.9A patent/CN108671069A/en not_active Withdrawn
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181019 |
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WW01 | Invention patent application withdrawn after publication |