CN108553520A - The Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice - Google Patents
The Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice Download PDFInfo
- Publication number
- CN108553520A CN108553520A CN201810733306.6A CN201810733306A CN108553520A CN 108553520 A CN108553520 A CN 108553520A CN 201810733306 A CN201810733306 A CN 201810733306A CN 108553520 A CN108553520 A CN 108553520A
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- CN
- China
- Prior art keywords
- materical crude
- medicine materical
- crude slice
- fresh
- chinese bulbul
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of " Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that:The Chinese bulbul medicinal material harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, crush, be sieved after be vacuum-packed.The water content of powder decoction pieces is less than 10%.Such prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule etc., is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Chinese bulbul medicine materical crude slice.
Background technology
The Chinese medicine Chinese bulbul is the ranunculaceae plant Chinese bulbulPulsatilla chinensis(Bge.)The dry root of Regel,
With clearing heat and detoxicating, the effect of removing heat from the blood and relieve diarrhea.This product is mainly used for toxic-heat and blood stasis, and the treatment under pruritus vulvae band is on tcm clinical practice
Common a herb.The processing method of traditional Chinese bulbul is:After medicinal material is excavated, silt is removed, it is dry, it is packaged, storage and transportation.It arrives
After medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice volume is big, and hygiene condition is poor, is easy to make moist, grow
It is mould, it is unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, clinical efficacy is difficult to ensure,
Patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping, carry
It is imperative with easy to use, rapid-action novel Chinese bulbul medicine materical crude slice.Existing market Chinese bulbul medicine materical crude slice, in addition to traditional medicine materical crude slice it
Outside, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality determines
In the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;Concentrated granular can only extract it is water-soluble at
Point.
Invention content
The invention discloses a kind of " Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that:In the Chinese bulbul
It after medicinal material harvesting, cleans in time, removal impurity and the dis-medicinal part such as silt, cleans and cut in taking advantage of using fresh herb tap water in 24 hours
At the piece of 2 ~ 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes,
Filtering, dregs pressing take juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction
It squeezes the juice again, collects concoction.Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, is concentrated into opposite
The concentrate that density is 1.02 ~ 1.10.The concentrate of gained is spray-dried, control dried object water content is powder within 10%
It is broken, 60 mesh sieve is crossed, is vacuum-packed to get finished product.Finished product medicine materical crude slice B containing pulchinenoside4(C59H96O26)No less than 5.0%.This powder
The clinical general usage amount of last medicine materical crude slice is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter pill, powder, capsule and piece
In agent, to substantially increase the convenience and compliance of Clinical practice, be conducive to the treatment of clinical acute disease.
The present invention solve traditional Chinese bulbul medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested,
The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular
Medicine materical crude slice is more preferable.
Specific embodiment
It after Chinese bulbul medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction
Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density.
The concentrate of gained is spray-dried, until water content is 10%, is crushed, 60 mesh sieve is crossed, is vacuum-packed to get finished product.Finished product medicine materical crude slice
B containing pulchinenoside4(C59H96O26)No less than 5.5%.
Claims (2)
1. a kind of Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that:It is net in time after the harvesting of Chinese bulbul medicinal material
Choosing, removal impurity and the dis-medicinal part such as silt add in the piece for taking advantage of using fresh herb tap water in 12 hours and cleaning and being cut into 2 ~ 5mm thickness
Enter the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and constantly stir 5 ~ 30 minutes, filtering, dregs pressing takes juice;In the gained dregs of a decoction again
The water of 5 ~ 10 times of weight is added, boils 10 ~ 30 minutes, filters while hot, the dregs of a decoction are squeezed the juice again, collect concoction;Merge above-mentioned concoction,
60 ~ 100 mesh sieve is crossed, is concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density;Gained concentrate is sprayed
Dry, control dried object water content is to be crushed within 10%, crosses 60 mesh sieve, is vacuum-packed to get finished product;Finished product medicine materical crude slice contains hoary hair
Father-in-law's saponin(e B4(C59H96O26)No less than 5.0%.
2. the Chinese bulbul according to claim 1 is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that:Clinic generally makes
Dosage is 1 ~ 5g, and such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733306.6A CN108553520A (en) | 2018-07-06 | 2018-07-06 | The Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733306.6A CN108553520A (en) | 2018-07-06 | 2018-07-06 | The Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108553520A true CN108553520A (en) | 2018-09-21 |
Family
ID=63555667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810733306.6A Withdrawn CN108553520A (en) | 2018-07-06 | 2018-07-06 | The Chinese bulbul is fresh to carry spray-dried powders medicine materical crude slice |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108553520A (en) |
-
2018
- 2018-07-06 CN CN201810733306.6A patent/CN108553520A/en not_active Withdrawn
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Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180921 |