CN108671172A - Trigone is fresh to carry vacuum drying powder decoction pieces - Google Patents

Trigone is fresh to carry vacuum drying powder decoction pieces Download PDF

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Publication number
CN108671172A
CN108671172A CN201810733379.5A CN201810733379A CN108671172A CN 108671172 A CN108671172 A CN 108671172A CN 201810733379 A CN201810733379 A CN 201810733379A CN 108671172 A CN108671172 A CN 108671172A
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China
Prior art keywords
trigone
decoction
fresh
water
vacuum drying
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Application number
CN201810733379.5A
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Chinese (zh)
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徐漫
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Individual
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Individual
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Priority to CN201810733379.5A priority Critical patent/CN108671172A/en
Publication of CN108671172A publication Critical patent/CN108671172A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a kind of " trigone is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:Trigone harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, after extracting solution is condensed into clear cream, then be dried under vacuum to water content be less than 10%, crush, be sieved after be vacuum-packed.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.

Description

Trigone is fresh to carry vacuum drying powder decoction pieces
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of trigone medicine materical crude slice.
Background technology
Sparganium stoloniferum is Sparganiaceae plant rhizoma scirpiSparganium stoloniferumBuch.-Ham. drying Stem tuber has the effect of blood-breaking, Xiao Ji Zhi Tong.This product Zhu Yong Yu abdominal mass and lump, dysmenorrhoea, blood stasis closed, chest impediment and cardialgia, The treatment of dyspepsia distending pain is a herb common on tcm clinical practice.The processing method of traditional trigone is:After medicinal material is excavated, It cleans, prunes crust, dry, be packaged, storage and transportation.To after medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice body Product is big, and Hygienic Standard is poor, is easy to make moist, mildew, is unfavorable for taking care of, storage and transportation cost are high.In addition, such trigone drink Tablet quality stability is poor, and clinical efficacy is difficult to ensure, patient takes inconvenience, works slow.Therefore, developing a kind of stable quality can Lean on, storage/transportation is at low cost, conducive to keeping, carry and easy to use, rapid-action novel trigone medicine materical crude slice, it is imperative.At present Trigone medicine materical crude slice in the market, other than traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but the two All it is using traditional medicine materical crude slice as raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve medicinal material pollution Problem;Concentrated granular can only extract water soluble ingredient.
Invention content
The invention discloses a kind of " trigone is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:It is harvested in trigone Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.15 ~ 1.25 clear cream.The clear cream of gained is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, is crushed, 60 mesh sieve is crossed, Vacuum packaging is to get finished product.The clinical general usage amount of this trigone medicine materical crude slice is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, also can be direct Enter in pill, powder, capsule and tablet, to substantially increase the convenience and compliance of Clinical practice, is conducive to clinic The treatment of acute disease.
The present invention solve traditional trigone medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.
Specific embodiment
It after trigone medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear Cream.It is 8% that the clear cream of gained is dried under vacuum to water content at 80 DEG C, is crushed, and crosses 60 mesh sieve, is vacuum-packed to get finished product.

Claims (2)

1. a kind of trigone is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:It after trigone harvesting, cleans, removes in time The impurity such as silt and dis-medicinal part are added 1 ~ 5 times in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness The water that 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice;5 ~ 10 are added in the gained dregs of a decoction The water of times weight, boils 10 ~ 30 minutes, filters while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;Merge above-mentioned concoction, crosses 60 ~ 100 Mesh sieves, and is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, is concentrated into the clear cream that relative density is 1.15 ~ 1.25;By the clear cream of gained 60 ~ It is dried under vacuum to water content at 80 DEG C and is less than 10%, crushes, crosses 60 mesh sieve, is vacuum-packed to get finished product.
2. trigone according to claim 1 is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:Clinic generally uses Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
CN201810733379.5A 2018-07-06 2018-07-06 Trigone is fresh to carry vacuum drying powder decoction pieces Withdrawn CN108671172A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810733379.5A CN108671172A (en) 2018-07-06 2018-07-06 Trigone is fresh to carry vacuum drying powder decoction pieces

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810733379.5A CN108671172A (en) 2018-07-06 2018-07-06 Trigone is fresh to carry vacuum drying powder decoction pieces

Publications (1)

Publication Number Publication Date
CN108671172A true CN108671172A (en) 2018-10-19

Family

ID=63813503

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810733379.5A Withdrawn CN108671172A (en) 2018-07-06 2018-07-06 Trigone is fresh to carry vacuum drying powder decoction pieces

Country Status (1)

Country Link
CN (1) CN108671172A (en)

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Application publication date: 20181019

WW01 Invention patent application withdrawn after publication