CN108635417A - The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces - Google Patents
The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces Download PDFInfo
- Publication number
- CN108635417A CN108635417A CN201810733343.7A CN201810733343A CN108635417A CN 108635417 A CN108635417 A CN 108635417A CN 201810733343 A CN201810733343 A CN 201810733343A CN 108635417 A CN108635417 A CN 108635417A
- Authority
- CN
- China
- Prior art keywords
- decoction
- chinese bulbul
- fresh
- water
- vacuum drying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241001504477 Pycnonotidae Species 0.000 title claims abstract description 18
- 239000000843 powder Substances 0.000 title claims abstract description 10
- 238000001291 vacuum drying Methods 0.000 title claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000006071 cream Substances 0.000 claims abstract description 7
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 7
- 239000002775 capsule Substances 0.000 claims abstract description 3
- 238000003306 harvesting Methods 0.000 claims abstract description 3
- 239000006187 pill Substances 0.000 claims abstract description 3
- 239000003826 tablet Substances 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 19
- 238000001914 filtration Methods 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims description 2
- 239000008399 tap water Substances 0.000 claims description 2
- 235000020679 tap water Nutrition 0.000 claims description 2
- 241001635598 Enicostema Species 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims 1
- 229930182490 saponin Natural products 0.000 claims 1
- 150000007949 saponins Chemical class 0.000 claims 1
- 239000000463 material Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000009461 vacuum packaging Methods 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 208000030090 Acute Disease Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000008350 Pruritus Vulvae Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of " Chinese bulbul is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that：The Chinese bulbul harvest after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, after extracting solution is condensed into clear cream, then be dried under vacuum to water content be less than 10%, crush, be sieved after be vacuum-packed.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Chinese bulbul medicine materical crude slice.
Background technology
The Chinese medicine Chinese bulbul is the ranunculaceae plant Chinese bulbulPulsatilla chinensis（Bge.）The dry root of Regel,
With clearing heat and detoxicating, the effect of removing heat from the blood and relieve diarrhea.This product is mainly used for toxic-heat and blood stasis, and the treatment under pruritus vulvae band is on tcm clinical practice
Common a herb.The processing method of traditional Chinese bulbul is：After medicinal material is excavated, silt is removed, it is dry, it is packaged, storage and transportation.It arrives
After medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice volume is big, and hygiene condition is poor, is easy to make moist, grow
It is mould, it is unfavorable for taking care of, storage and transportation cost are high.In addition, such Chinese bulbul prepared slice quality stability is poor, clinical efficacy is difficult to
It ensures, patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to protect
Pipe, carrying and easy to use, rapid-action novel Chinese bulbul medicine materical crude slice, it is imperative.Chinese bulbul medicine materical crude slice currently on the market, in addition to
Except traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material,
Its quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only extract
Go out water soluble ingredient.
Invention content
The invention discloses a kind of " Chinese bulbul is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that：In the Chinese bulbul
After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~
The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering,
Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.15 ~ 1.25 clear cream.The clear cream of gained is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, is crushed, 60 mesh sieve is crossed,
Vacuum packaging is to get finished product.Finished product medicine materical crude slice B containing pulchinenoside4（C59H96O26）No less than 5.0%.This Chinese bulbul medicine materical crude slice is clinical
General usage amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet, to
The convenience and compliance for substantially increasing Clinical practice, are conducive to the treatment of clinical acute disease.
The present invention solve traditional Chinese bulbul medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested,
The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular
Medicine materical crude slice is more preferable.
Specific embodiment
It after Chinese bulbul medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction
Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.20 to be concentrated into relative density
Clear cream.It is 8% that the clear cream of gained is dried under vacuum at 80 DEG C to water content, is crushed, and crosses 60 mesh sieve, vacuum packaging to get at
Product.Finished product medicine materical crude slice B containing pulchinenoside4（C59H96O26）No less than 5.0%.
Claims (2)
1. a kind of Chinese bulbul is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that：After the Chinese bulbul harvests, clean in time,
Impurity and the dis-medicinal part such as silt are removed, in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness, addition 1 ~
The water of 5 times of 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice；5 are added in the gained dregs of a decoction
The water of ~ 10 times of weight is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction；Merge above-mentioned concoction, cross 60 ~
100 mesh sieve, and are concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, are concentrated into the clear cream that relative density is 1.15 ~ 1.25；The clear cream of gained is existed
It is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, crushes, crosses 60 mesh sieve, is vacuum-packed to get finished product；Finished product medicine materical crude slice is containing white
Head father-in-law's saponin(e B4（C59H96O26）No less than 5.0%.
2. the Chinese bulbul according to claim 1 is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that：Clinic generally makes
Dosage is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810733343.7A CN108635417A (en) | 2018-07-06 | 2018-07-06 | The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810733343.7A CN108635417A (en) | 2018-07-06 | 2018-07-06 | The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108635417A true CN108635417A (en) | 2018-10-12 |
Family
ID=63751171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810733343.7A Pending CN108635417A (en) | 2018-07-06 | 2018-07-06 | The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108635417A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107362182A (en) * | 2017-08-25 | 2017-11-21 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of phoenix-tail fern |
| CN107412303A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
| CN107432883A (en) * | 2017-08-25 | 2017-12-05 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed |
| CN107582624A (en) * | 2017-08-25 | 2018-01-16 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin |
| CN108186690A (en) * | 2018-03-21 | 2018-06-22 | 山西省医药与生命科学研究院 | A kind of Chinese medicine processing method |
-
2018
- 2018-07-06 CN CN201810733343.7A patent/CN108635417A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107362182A (en) * | 2017-08-25 | 2017-11-21 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of phoenix-tail fern |
| CN107412303A (en) * | 2017-08-25 | 2017-12-01 | 芜湖天成普阳中药科技有限公司 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium |
| CN107432883A (en) * | 2017-08-25 | 2017-12-05 | 徐漫 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed |
| CN107582624A (en) * | 2017-08-25 | 2018-01-16 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin |
| CN108186690A (en) * | 2018-03-21 | 2018-06-22 | 山西省医药与生命科学研究院 | A kind of Chinese medicine processing method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181012 |
|
| WD01 | Invention patent application deemed withdrawn after publication |