CN107432883A - A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed - Google Patents

A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed Download PDF

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Publication number
CN107432883A
CN107432883A CN201710738584.6A CN201710738584A CN107432883A CN 107432883 A CN107432883 A CN 107432883A CN 201710738584 A CN201710738584 A CN 201710738584A CN 107432883 A CN107432883 A CN 107432883A
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CN
China
Prior art keywords
lopseed
vacuum drying
fresh
squeezing
decoction pieces
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CN201710738584.6A
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Chinese (zh)
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徐漫
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Individual
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Priority to CN201710738584.6A priority Critical patent/CN107432883A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed.The technique is cleaned, eluted after the harvesting of lopseed medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo, is vacuum-packed after crushing.Lopseed powder decoction pieces prepared by this method, remain the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.

Description

A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese Drug Tou Gu Cao medicine materical crude slice.
Background technology
Chinese Drug Tou Gu Cao is the herb of euphorbia plant speranskia tuberculata.The effect of with expelling wind and eliminating dampness, promoting blood circulation and stopping pain.
The processing mode of conventional lopseed medicine materical crude slice is:Impurity is removed after harvesting, is dried, directly packing storage and transport. These dry lopseed Hygienic Indexes can not be up to standard, easily occur medicinal material go mouldy, so as to cause the decline of medical material quanlity and The reduction of clinical efficacy.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily occur it is rotten and contaminated, quality it is difficult to ensure that, be unfavorable for adjusting Agent prescription and ensure its clinical efficacy.
At present, in the market also has the manufactured granule pieces sale after extraction of lopseed medicinal material.The preparation of granule pieces Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried Take out.Further, since the lopseed medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient Loss is also very big.In order to ensure lopseed medicinal material clinic effectively, steady quality, a kind of new lopseed medicine materical crude slice and its Preparation technology urgently develops.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed ".This technique can be most The polarity and the nonpolar active ingredient that retain in lopseed medicinal material of limits, avoid medicinal material from being processed and accumulating in existing medicine materical crude slice During the loss of caused active ingredient and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, it is deep to ensuring The steady quality and clinical safety of careless medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that:
Its herb is gathered in lopseed picking time, is cleaned, after washing, is cut into 1 ~ 2cm section, adds 0.5 ~ 2 times of amount of medicinal material amount Water, stir 5 ~ 10 minutes, take advantage of fresh squeezing, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, merge medicine twice Juice, 40 ~ 120 mesh screens, obtain lopseed concoction.Obtained lopseed concoction is concentrated under reduced pressure into phase under the conditions of 40 ~ 75 DEG C To the medicinal extract that density is 1.05 ~ 1.30, and 60 ~ 120 mesh sieves are crushed after it is dried in vacuo 48 ~ 72 hours in 40 ~ 70 DEG C, very Empty package, produce fresh squeeze of lopseed and be dried in vacuo powder decoction pieces.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture, The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Lopseed is enclosed in bag Thin layer differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, Quick Response Code is printed on, can be linked by scanning and obtain the former plant photo of product, medicinal material photo, medicine materical crude slice photo, character and micro- The information such as diagnostic characteristics.
The present invention is advantageous in that:
The lopseed medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being dried in vacuo, resulting powder Last medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume significantly Ground reduces, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, and there is very significant society to anticipate Justice and economic implications.
Embodiment
Embodiment 1
By the lopseed medicinal material of fresh collection, clean, silt is washed with water, be cut into 1cm section, add the water of 1 times of amount, stirring 5min, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add the water of 5 times of amounts, stir 20min, press extracting juice.By above-mentioned 2 times Concoction merges, with 100 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 65 DEG C.It is in medicinal extract relative density obtained by concentration When 1.10, it is transferred in vacuum drying chamber, is dried 48 hours in 75 DEG C, low-temperature grinding, moisture is not higher than 12%.
Embodiment 2
By the lopseed medicinal material of fresh collection, clean, silt is washed with water, be cut into 2cm section, add the water of 2 times of amounts, stirring 10min, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add the water of 10 times of amounts, stir 30min, press extracting juice.By above-mentioned 2 Secondary concoction merges, with 80 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 70 DEG C.In medicinal extract relative density obtained by concentration For 1.15 when, be transferred in vacuum drying chamber, in 70 DEG C dry 72 hours, low-temperature grinding, moisture be not higher than 12%.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected Within the scope of.

Claims (2)

  1. A kind of 1. fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed, it is characterised in that:Gathered in lopseed picking time Its herb, is cleaned, and after washing, is cut into 1 ~ 2cm section, is added the water of 0.5 ~ 2 times of amount of medicinal material amount, stirs 5 ~ 10 minutes, take advantage of fresh pressure Squeeze, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, merge concoction twice, 40 ~ 120 mesh screens, obtain Bone herbal medicine juice.
  2. A kind of 2. fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed according to claim 1, it is characterised in that: By obtained lopseed concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density be 1.05 ~ 1.30 medicinal extract, and by its in 40 ~ 70 DEG C vacuum drying 48 ~ 72 hours after crushed 60 ~ 120 mesh sieves, be vacuum-packed, produce lopseed it is fresh squeeze vacuum drying powder Last medicine materical crude slice.
CN201710738584.6A 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed Pending CN107432883A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710738584.6A CN107432883A (en) 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710738584.6A CN107432883A (en) 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed

Publications (1)

Publication Number Publication Date
CN107432883A true CN107432883A (en) 2017-12-05

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CN201710738584.6A Pending CN107432883A (en) 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed

Country Status (1)

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CN (1) CN107432883A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108524569A (en) * 2018-07-06 2018-09-14 徐漫 Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces
CN108619430A (en) * 2018-07-06 2018-10-09 徐漫 Smilax is fresh to carry vacuum drying powder decoction pieces
CN108619226A (en) * 2018-07-06 2018-10-09 徐漫 Pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice
CN108619255A (en) * 2018-07-06 2018-10-09 徐漫 Rheum officinale is fresh to carry spray-dried powders medicine materical crude slice
CN108619235A (en) * 2018-07-06 2018-10-09 徐漫 Radix scutellariae is fresh to carry spray-dried powders medicine materical crude slice
CN108619267A (en) * 2018-07-06 2018-10-09 徐漫 The coptis is fresh to carry spray-dried powders medicine materical crude slice
CN108619357A (en) * 2018-07-06 2018-10-09 徐漫 Chinese yam is fresh to carry spray-dried powders medicine materical crude slice
CN108619231A (en) * 2018-07-06 2018-10-09 徐漫 Radix Salviae Miltiorrhizae is fresh to carry spray-dried powders medicine materical crude slice
CN108635417A (en) * 2018-07-06 2018-10-12 徐漫 The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces
CN108671196A (en) * 2018-07-06 2018-10-19 徐漫 Radix Curcumae is fresh to carry spray-dried granules medicine materical crude slice
CN108671152A (en) * 2018-07-06 2018-10-19 徐漫 Rhizoma Gastrodiae is fresh to carry spray-dried powders medicine materical crude slice

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105998133A (en) * 2016-07-23 2016-10-12 徐漫 Chinese lobelia freshly-squeezed vacuum drying powder decoction tablets and preparation process thereof
CN106109723A (en) * 2016-07-23 2016-11-16 徐漫 A kind of Herba Verbenae is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof
CN106109544A (en) * 2016-07-24 2016-11-16 徐漫 A kind of Herba Euphorbiae Humifusae is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof
CN106109596A (en) * 2016-07-23 2016-11-16 徐自升 A kind of Herba Plantaginis is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105998133A (en) * 2016-07-23 2016-10-12 徐漫 Chinese lobelia freshly-squeezed vacuum drying powder decoction tablets and preparation process thereof
CN106109723A (en) * 2016-07-23 2016-11-16 徐漫 A kind of Herba Verbenae is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof
CN106109596A (en) * 2016-07-23 2016-11-16 徐自升 A kind of Herba Plantaginis is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof
CN106109544A (en) * 2016-07-24 2016-11-16 徐漫 A kind of Herba Euphorbiae Humifusae is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108524569A (en) * 2018-07-06 2018-09-14 徐漫 Radix Notoginseng is fresh to carry vacuum drying powder decoction pieces
CN108619430A (en) * 2018-07-06 2018-10-09 徐漫 Smilax is fresh to carry vacuum drying powder decoction pieces
CN108619226A (en) * 2018-07-06 2018-10-09 徐漫 Pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice
CN108619255A (en) * 2018-07-06 2018-10-09 徐漫 Rheum officinale is fresh to carry spray-dried powders medicine materical crude slice
CN108619235A (en) * 2018-07-06 2018-10-09 徐漫 Radix scutellariae is fresh to carry spray-dried powders medicine materical crude slice
CN108619267A (en) * 2018-07-06 2018-10-09 徐漫 The coptis is fresh to carry spray-dried powders medicine materical crude slice
CN108619357A (en) * 2018-07-06 2018-10-09 徐漫 Chinese yam is fresh to carry spray-dried powders medicine materical crude slice
CN108619231A (en) * 2018-07-06 2018-10-09 徐漫 Radix Salviae Miltiorrhizae is fresh to carry spray-dried powders medicine materical crude slice
CN108635417A (en) * 2018-07-06 2018-10-12 徐漫 The Chinese bulbul is fresh to carry vacuum drying powder decoction pieces
CN108671196A (en) * 2018-07-06 2018-10-19 徐漫 Radix Curcumae is fresh to carry spray-dried granules medicine materical crude slice
CN108671152A (en) * 2018-07-06 2018-10-19 徐漫 Rhizoma Gastrodiae is fresh to carry spray-dried powders medicine materical crude slice

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Application publication date: 20171205

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