CN107441223A

CN107441223A - A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia

Info

Publication number: CN107441223A
Application number: CN201710739153.1A
Authority: CN
Inventors: 徐自升
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-08-25
Filing date: 2017-08-25
Publication date: 2017-12-08

Abstract

The invention discloses a kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia.The technique is cleaned, eluted after Herba Houttuyniae harvesting, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is spray-dried, and collects spray drying product, through crushing with just squeezing concoction mixing granulation, is vacuum-packed after whole grain.Cordate houttuynia granule pieces prepared by this method, remain the polarity in medicinal material and nonpolar active ingredient to greatest extent.Granule pieces good fluidity, beneficial to accumulating, convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.

Description

A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia

Technical field

The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese Medicinal Houttuynia Cordata Thunb medicine materical crude slice.

Background technology

Chinese Medicinal Houttuynia Cordata Thunb is saururus chinensis standing grain bucket plant heartleaf houttuyniaHouttuynia cordataThunb. fresh herb or dry Dry aerial part.This product acrid flavour, cold, return lung warp.There is this product clearing heat and detoxicating, detumescence treatment sore, promoting urination and removing dampness, heat-clearing to stop The effect of dysentery, stomach strengthening and digestion promoting, clinic can be used to treat real heat, heat toxin, damp evil, disease heat as the lung carbuncle of trouble, sore swollen toxin, hemorrhoid just Blood, retention of heat in the spleen and stomach etc..

The processing mode of conventional cordate houttuynia medicine materical crude slice is：The luxuriant flower spike of summer cauline leaf is tapped when more, is removed impurity, is dried, Pack again accumulating.Medicine materical crude slice factory process when again with water wash, segment, dry.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily pollution and Go mouldy, quality it is difficult to ensure that, be unfavorable for formula and adjust and ensure its clinical efficacy, or even the harm of recessiveness is brought to patient.

At present, in the market also has Herba Houttuyniae manufactured granule pieces sale after extraction.The preparation of granule pieces Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried Take out.Further, since the Herba Houttuyniae of extraction is also to dry and by storage for a long time, therefore, active ingredient Loss is also very big.In order to ensure the clinic of Herba Houttuyniae is effective, steady quality, a kind of new cordate houttuynia medicine materical crude slice is urgently Exploitation.

The content of the invention

The invention discloses " a kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia ".This technique can be most The polarity and the nonpolar active ingredient that retain in Herba Houttuyniae of limits, avoid medicinal material from being processed and accumulating in existing medicine materical crude slice During the loss of caused active ingredient and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, to ensuring fish raw meat The steady quality and clinical safety of careless medicine materical crude slice effectively have great importance.

To achieve these goals, the technical scheme is that：

Its aerial part is gathered in cordate houttuynia picking time, is cleaned, is cut into 1 ~ 2cm section, adds 0.5 ~ 1 times of amount of medicinal material weight Water, stir 15 ~ 30 minutes, take advantage of fresh squeezing, collect and just squeeze concoction, the first squeezing concoction of 0.1% ~ 0.5% weight of retention is standby, and the dregs of a decoction add Enter the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, the remaining dregs of a decoction add the water of 1 ~ 5 times of amount, press extracting juice, merge just Squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain cordate houttuynia concoction.By obtained cordate houttuynia concoction in 40 ~ 75 Relative density is concentrated under reduced pressure under the conditions of DEG C and is 1.02 ~ 1.15 concentrate, and this concentrate is spray-dried, intake air temperature It is set as 90 ~ 140 DEG C, air outlet temperature is 80 ~ 110 DEG C, collects desciccate, and 60 ~ 100 mesh sieves are crossed after crushing.By above-mentioned fish Raw meat grass spray dried powder, mixed with the first squeezing concoction of retention, prepare softwood, pelletized, 50 ~ 80 DEG C of dryings 4 ~ 8 hours, whole grain, very Empty package.On the label of product packaging bags, the name of an article, medicinal part, planting site, medicine materical crude slice manufacturer, date of manufacture, master in printing Want the information such as component content, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Cordate houttuynia is enclosed in bag Thin layer differentiates collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, print There is Quick Response Code, former plant photo, medicinal material photo, medicine materical crude slice photo, character and the micro- mirror for obtaining product can be linked by scanning The information such as other feature.

The present invention is advantageous in that：

The Herba Houttuyniae of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being spray-dried, pelletizing, gained The granule pieces arrived, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume is compared to traditional medicine materical crude slice body Product greatly reduces, good fluidity, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, has ten Divide significant social effect and economic implications.

Embodiment

Embodiment 1

By the Herba Houttuyniae of fresh collection, clean, silt is washed with water, be cut into 1cm section, add 0.5 times of amount of medicinal material weight Water, stir 15 minutes, take advantage of fresh squeezing, the first squeezing concoction for retaining 0.1% weight is separately used.The gained dregs of a decoction add the running water of 3 times of amounts, Stir 20min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.By above-mentioned remaining just squeezing medicine Juice merges with the follow-up concoction of squeezing twice, with 100 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 65 DEG C.In concentration institute Medicinal extract relative density be 1.05 when, spray drying, intake air temperature be 140 DEG C, air outlet temperature be 100 DEG C, collect spray drying Thing, low-temperature grinding, cross 80 mesh sieves.This spray dried powder is mixed into softwood processed with the first squeezing concoction of above-mentioned retention, pelletized, 75 DEG C dry Dry 6 hours, whole grain, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.

Embodiment 2

By the Herba Houttuyniae of fresh collection, clean, silt is washed with water, be cut into 2cm section, add 1 times of amount of medicinal material weight Water, stir 30 minutes, take advantage of fresh squeezing, the first squeezing concoction for retaining 0.5% weight is separately used.The gained dregs of a decoction add the running water of 5 times of amounts, stir Mix 30min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.By above-mentioned remaining just squeezing concoction Merge with subsequently squeezing concoction twice, with 100 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 70 DEG C.Obtained by concentration When medicinal extract relative density is 1.10, spray drying, intake air temperature is 120 DEG C, and air outlet temperature is 90 DEG C, collects spray drying thing, Low-temperature grinding, cross 80 mesh sieves.This spray dried powder is mixed into softwood processed with the first squeezing concoction of above-mentioned retention, pelletized, 70 DEG C of dryings 8 Hour, whole grain, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.

Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected Within the scope of.

Claims

A kind of 1. fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia, it is characterised in that：Gathered in cordate houttuynia picking time Its aerial part, clean, be cut into 1 ~ 2cm section, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 minutes, take advantage of fresh pressure Squeezing, to collect and just squeeze concoction, the first squeezing concoction of 0.1% ~ 0.5% weight of retention is standby, the water of the dregs of a decoction 1 ~ 5 times of amount of addition, stirring 5 ~ 30min, press extracting juice, the remaining dregs of a decoction add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze medicine twice Juice, 100 ~ 200 mesh screens, obtain cordate houttuynia concoction.
A kind of 2. fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia according to claim 1, it is characterised in that： By obtained cordate houttuynia concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density be 1.02 ~ 1.15 concentrate, and by this Concentrate is spray-dried, and intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, collects desciccate, powder 60 ~ 100 mesh sieves are crossed after broken.
A kind of 3. fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia according to claim 1, it is characterised in that： By the cordate houttuynia spray dried powder in claim 2, mixed with the first squeezing concoction retained in claim 1, prepare softwood, made Grain, 50 ~ 80 DEG C of dryings 4 ~ 8 hours, whole grain, vacuum packaging.