CN107441131A

CN107441131A - A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium

Info

Publication number: CN107441131A
Application number: CN201710739193.6A
Authority: CN
Inventors: 徐自升
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-08-25
Filing date: 2017-08-25
Publication date: 2017-12-08

Abstract

The invention discloses a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium.The technique is cleaned, eluted after the harvesting of desmodium medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is spray-dried, and collects spray drying product, is vacuum-packed after crushed.Christina Loosestrife medicine materical crude slice prepared by this method, remains the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.

Description

A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium

Technical field

The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine desmodium medicine materical crude slice.

Background technology

Chinese medicine desmodium is Ofthe Primulaceae Lysimachia christinaeLysimachia christinaeHance drying herb. This product has the effect of promoting diuresis for stranguria, clearing heat and detoxicating, eliminating stasis to subdue swelling, is mainly used in treating liver and gall and calculi in urinary system, ephritis Oedema, jaundice with damp-heat pathogen, snake bite and insect sting, traumatic injury etc..

The processing mode of common desmodium medicine materical crude slice is：Summer, the harvesting of season in autumn two, remove impurity, dry, then accumulating of packing. Such prepared herbal medicine in small pieces ready for decoction, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, quality it is difficult to ensure that, be unfavorable for formula adjust With ensure its clinical efficacy, or even the harm of recessiveness is brought to patient.

At present, in the market also has the manufactured granule pieces sale after extraction of desmodium medicinal material.The preparation of granule pieces Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried Take out.Further, since the desmodium medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient Loss is also very big.In order to ensure the clinic of desmodium medicinal material is effective, steady quality, a kind of new desmodium medicine materical crude slice is urgently Exploitation.

The content of the invention

The invention discloses " a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium ".This technique can be most While limits retain money herbal medicine material in polarity and nonpolar active ingredient, avoid medicinal material existing medicine materical crude slice processing and The decline of the loss of caused active ingredient and medical material quanlity in storage and transport process, pollution of the medicinal material by mould etc. is reduced, to ensuring The steady quality and clinical safety of desmodium medicine materical crude slice effectively have great importance.

To achieve these goals, the technical scheme is that：

Its herb is gathered in desmodium picking time, is cleaned, is cut into 1 ~ 2cm section, the water of 0.5 ~ 1 times of amount of medicinal material weight is added, stirs Mix 15 ~ 30 minutes, take advantage of fresh squeezing, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, institute The surplus dregs of a decoction add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction, 100 ~ 200 mesh sieve mistakes twice Filter, obtains desmodium concoction.By obtained desmodium concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density for 1.02 ~ 1.15 concentrate, and this concentrate is spray-dried, intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, desciccate is collected, 60 ~ 100 mesh sieves, vacuum packaging are crossed after crushing.

On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture, The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Desmodium is enclosed in bag Thin layer differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, Quick Response Code is printed on, can be linked by scanning and obtain the former plant photo of product, medicinal material photo, medicine materical crude slice photo, character and micro- The information such as diagnostic characteristics.

The present invention is advantageous in that：

The desmodium medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being spray-dried, resulting powder Last medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume significantly Ground reduces, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, and there is very significant society to anticipate Justice and economic implications.

Embodiment

Embodiment 1

By the desmodium medicinal material of fresh collection, its herb is gathered in desmodium picking time, is cleaned, is cut into 1cm section, adds medicinal material The water of 0.5 times of amount of weight, is stirred 15 minutes, takes advantage of fresh squeezing, is collected and is just squeezed concoction, and the dregs of a decoction add the water of 5 times of amounts, stir 5min, Press extracting juice, the remaining dregs of a decoction add the water of 1 ~ 5 times of amount, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 Mesh screen, obtain desmodium concoction.Concoction is concentrated under reduced pressure, and temperature is set as 65 DEG C.It is in medicinal extract relative density obtained by concentration When 1.05, spray drying, intake air temperature is 140 DEG C, and air outlet temperature is 100 DEG C, collects spray drying thing, low-temperature grinding, crosses 80 Mesh sieve, moisture are not higher than 12%, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.

Embodiment 2

By the desmodium medicinal material of fresh collection, its herb is gathered in desmodium picking time, is cleaned, is cut into 2cm section, adds medicinal material The water of 1 times of amount of weight, is stirred 30 minutes, takes advantage of fresh squeezing, is collected and is just squeezed concoction, and the dregs of a decoction add the water of 3 times of amounts, stirs 10min, pressure Extracting juice, the remaining dregs of a decoction add 3 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction, 100 mesh sieves twice Filtering, obtains desmodium concoction.Concoction is concentrated under reduced pressure, and temperature is set as 70 DEG C.When medicinal extract relative density obtained by concentration is 1.10, Spray drying, intake air temperature are 120 DEG C, and air outlet temperature is 90 DEG C, collect spray drying thing, low-temperature grinding, cross 60 mesh sieves, moisture Content is not higher than 12%, pack, 1kg/ bags, adds packed antioxidant and drier, Vacuum Package, labeling.

Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected Within the scope of.

Claims

A kind of 1. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium, it is characterised in that：Gathered in desmodium picking time Its herb, clean, be cut into 1 ~ 2cm section, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 minutes, take advantage of fresh squeezing, receive Collection just squeeze concoction, the dregs of a decoction add 1 ~ 5 times amount water, stir 5 ~ 30min, press extracting juice, the remaining dregs of a decoction add 1 ~ 5 times amount Water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain desmodium concoction.
A kind of 2. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of desmodium according to claim 1, it is characterised in that： By obtained desmodium concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density be 1.02 ~ 1.15 concentrate, and by this Concentrate is spray-dried, and intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, collects desciccate, powder 60 ~ 100 mesh sieves, vacuum packaging are crossed after broken.