CN107334797A - A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper - Google Patents
A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper Download PDFInfo
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- CN107334797A CN107334797A CN201710739075.5A CN201710739075A CN107334797A CN 107334797 A CN107334797 A CN 107334797A CN 201710739075 A CN201710739075 A CN 201710739075A CN 107334797 A CN107334797 A CN 107334797A
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- Prior art keywords
- trumpet creeper
- chinese trumpet
- squeezing
- materical crude
- crude slice
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Alternative & Traditional Medicine (AREA)
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- Medical Informatics (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper.The technique is cleaned, eluted after the harvesting of Chinese trumpet creeper medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is spray-dried, and collects spray drying product, is vacuum-packed after crushed.Chinese trumpet creeper powder decoction pieces prepared by this method, remain the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine Chinese trumpet creeper medicine materical crude slice.
Background technology
Chinese medicine Chinese trumpet creeper is that crape myrtle section plant is reached the cloudsCampsis grandiflora(Thunb.) K.Schum. or U.S.
Reach the clouds in continentCampsis radicans (L.) drying for Seem. is spent.This product has promoting circulation of blood dissolving stasis, the effect of cooling blood, expelling wind.Mainly
For Amenorrhea, postpartum breast is swollen, and rubella is rubescent, pruitus, the treatment of acne etc..
The processing mode of conventional Chinese trumpet creeper medicine materical crude slice is：Summer, season in autumn two pluck when spending in full bloom, dry, then accumulating of packing.This
Class medicine materical crude slice, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, quality it is difficult to ensure that, be unfavorable for formula adjust and ensure
Its clinical efficacy, or even recessive harm is brought to patient.
At present, in the market also has the manufactured granule pieces sale after extraction of Chinese trumpet creeper medicinal material.The preparation of granule pieces
Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried
Take out.Further, since the Chinese trumpet creeper medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient
Loss is also very big.In order to ensure the clinic of Chinese trumpet creeper medicinal material is effective, steady quality, a kind of new Chinese trumpet creeper medicine materical crude slice is urgently
Exploitation.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper ".This technique can be most
While limits retain Chinese trumpet creeper medicinal material in polarity and nonpolar active ingredient, avoid medicinal material existing medicine materical crude slice processing and
The decline of the loss of caused active ingredient and medical material quanlity in storage and transport process, pollution of the medicinal material by mould etc. is reduced, to ensuring
The steady quality and clinical safety of Chinese trumpet creeper medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that：
After Chinese trumpet creeper harvesting, clean, be cut into 1 ~ 2cm section, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 points
Clock, fresh squeezing is taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, the remaining dregs of a decoction are again
Add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, must reach the clouds
Flower pesticide juice.Obtained Chinese trumpet creeper concoction is concentrated under reduced pressure into the concentration that relative density is 1.02 ~ 1.15 under the conditions of 40 ~ 75 DEG C
Liquid, and this concentrate is spray-dried, intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, collects dry
Dry product, 60 ~ 100 mesh sieves, vacuum packaging are crossed after crushing.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture,
The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Chinese trumpet creeper is enclosed in bag
Thin layer differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product,
Quick Response Code is printed on, can be linked by scanning and obtain the former plant photo of product, medicinal material photo, medicine materical crude slice photo, character and micro-
The information such as diagnostic characteristics.
The present invention is advantageous in that：
The Chinese trumpet creeper medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being spray-dried, resulting powder
Last medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume significantly
Ground reduces, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, and there is very significant society to anticipate
Justice and economic implications.
Embodiment
Embodiment 1
By the Chinese trumpet creeper medicinal material of fresh collection, clean, be cut into 1cm section, add the water of 0.5 times of amount of medicinal material weight, stir 15 points
Clock, fresh squeezing is taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 5 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 5
Times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain Chinese trumpet creeper concoction.It will insult
Clouds flower pesticide juice is concentrated under reduced pressure, and temperature is set as 65 DEG C.When medicinal extract relative density obtained by concentration is 1.05, spray drying, air intake
Mouth temperature is 140 DEG C, and air outlet temperature is 100 DEG C, collects spray drying thing, and low-temperature grinding crosses 80 mesh sieves, and moisture is not higher than
12%, pack, 1kg/ bags, add packed antioxidant and drier, Vacuum Package, labeling.
Embodiment 2
By the Chinese trumpet creeper medicinal material of fresh collection, clean, be cut into 2cm section, add the water of 1 times of amount of medicinal material weight, stir 30 minutes,
Fresh squeezing is taken advantage of, collects and just squeezes concoction, the dregs of a decoction add the water of 3 times of amounts, stir 10min, press extracting juice, and the remaining dregs of a decoction add 5 times
The water of amount, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain Chinese trumpet creeper concoction.It will reach the clouds
Flower pesticide juice is concentrated under reduced pressure, and temperature is set as 70 DEG C.When medicinal extract relative density obtained by concentration is 1.10, spray drying, air inlet
Temperature is 120 DEG C, and air outlet temperature is 90 DEG C, collects spray drying thing, low-temperature grinding, crosses 60 mesh sieves, and moisture is not higher than 12%,
Pack, 1kg/ bags, adds packed antioxidant and drier, Vacuum Package, labeling.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
- A kind of 1. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper, it is characterised in that：After Chinese trumpet creeper harvesting, wash Only, 1 ~ 2cm section is cut into, adds the water of 0.5 ~ 1 times of amount of medicinal material weight, is stirred 15 ~ 30 minutes, takes advantage of fresh squeezing, collects and just squeezes medicine Juice, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, and the remaining dregs of a decoction add the water of 1 ~ 5 times of amount, and squeezing takes Juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain Chinese trumpet creeper concoction.
- A kind of 2. fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper according to claim 1, it is characterised in that： By the Chinese trumpet creeper concoction obtained in claim 1 be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density be 1.02 ~ 1.15 it is dense Contracting liquid, and this concentrate is spray-dried, intake air temperature is set as 90 ~ 140 DEG C, and air outlet temperature is 80 ~ 110 DEG C, is collected Desciccate, 60 ~ 100 mesh sieves, vacuum packaging are crossed after crushing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710739075.5A CN107334797A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710739075.5A CN107334797A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107334797A true CN107334797A (en) | 2017-11-10 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710739075.5A Pending CN107334797A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Chinese trumpet creeper |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213460A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Radix et Caulis Opuntiae Dillenii fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
| CN105213551A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN105213660A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN105287860A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower spray-dried powdery decoction piece and preparation technology thereof |
| CN105520986A (en) * | 2016-02-11 | 2016-04-27 | 徐自升 | Folium artemisiae argyi fresh juice spray-dried decoction powder and preparation process thereof |
-
2017
- 2017-08-25 CN CN201710739075.5A patent/CN107334797A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213460A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Radix et Caulis Opuntiae Dillenii fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
| CN105213551A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN105213660A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
| CN105287860A (en) * | 2015-11-22 | 2016-02-03 | 徐漫 | Freshly-squeezed paulownia flower spray-dried powdery decoction piece and preparation technology thereof |
| CN105520986A (en) * | 2016-02-11 | 2016-04-27 | 徐自升 | Folium artemisiae argyi fresh juice spray-dried decoction powder and preparation process thereof |
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Application publication date: 20171110 |