CN107334814A - A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb - Google Patents

A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb Download PDF

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Publication number
CN107334814A
CN107334814A CN201710739055.8A CN201710739055A CN107334814A CN 107334814 A CN107334814 A CN 107334814A CN 201710739055 A CN201710739055 A CN 201710739055A CN 107334814 A CN107334814 A CN 107334814A
Authority
CN
China
Prior art keywords
ground ivy
longtube ground
ivy herb
squeezing
concoction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710739055.8A
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Chinese (zh)
Inventor
黄竹青
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Original Assignee
Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd filed Critical Wuhu Tiancheng Puyang Traditional Chinese Medicine Technology Co Ltd
Priority to CN201710739055.8A priority Critical patent/CN107334814A/en
Publication of CN107334814A publication Critical patent/CN107334814A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb.The technique is cleaned, eluted after the harvesting of Longtube Ground Ivy Herb medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo, is vacuum-packed after crushing.Longtube Ground Ivy Herb medicine materical crude slice prepared by this method, remains the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.

Description

A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine Longtube Ground Ivy Herb medicine materical crude slice.
Background technology
Chinese medicine Longtube Ground Ivy Herb is labiate blood circulation promoting pillGlechoma longituba (Nakai) Kupr. dry ground Upper part.This product has that dampness removing is treating stranguria, clearing heat and detoxicating, the effect of eliminating stasis to subdue swelling, is swollen for heat gonorrhea, urolithiasis, jaundice with damp-heat pathogen, sore carbuncle Bitterly, the treatment of traumatic injury etc..
The processing mode of common Longtube Ground Ivy Herb medicine materical crude slice is:Spring to autumn harvests, and removes impurity, dries, then accumulating of packing.This Class prepared herbal medicine in small pieces ready for decoction, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, quality it is difficult to ensure that, be unfavorable for formula adjust and Ensure its clinical efficacy, or even the harm of recessiveness is brought to patient.
At present, in the market also has the manufactured granule pieces sale after extraction of Longtube Ground Ivy Herb medicinal material.The preparation of granule pieces Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried Take out.Further, since the Longtube Ground Ivy Herb medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient Loss is also very big.In order to ensure the clinic of Longtube Ground Ivy Herb medicinal material is effective, steady quality, a kind of new Longtube Ground Ivy Herb medicine materical crude slice is urgently Exploitation.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb ".This technique can be most While limits retain Longtube Ground Ivy Herb medicinal material in polarity and nonpolar active ingredient, avoid medicinal material existing medicine materical crude slice processing and The decline of the loss of caused active ingredient and medical material quanlity in storage and transport process, pollution of the medicinal material by mould etc. is reduced, to ensuring The steady quality and clinical safety of Longtube Ground Ivy Herb medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that:
Its herb is gathered in Longtube Ground Ivy Herb picking time, is cleaned, is cut into 1 ~ 2cm section, the water of 0.5 ~ 1 times of amount of medicinal material weight is added, stirs Mix 15 ~ 30 minutes, take advantage of fresh squeezing, collect and just squeeze concoction, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, institute The surplus dregs of a decoction add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction, 100 ~ 200 mesh sieve mistakes twice Filter, obtains Longtube Ground Ivy Herb concoction.By obtained Longtube Ground Ivy Herb concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density for 1.05 ~ 1.30 medicinal extract, and 60 ~ 120 mesh sieves are crushed after it is dried in vacuo 4 ~ 8 hours in 40 ~ 70 DEG C, it is vacuum-packed, the company's of producing money Grass is fresh to squeeze vacuum drying powder decoction pieces.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture, The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Longtube Ground Ivy Herb is enclosed in bag Thin layer differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product, Quick Response Code is printed on, can be linked by scanning and obtain the former plant photo of product, medicinal material photo, medicine materical crude slice photo, character and micro- The information such as diagnostic characteristics.
The present invention is advantageous in that:
The Longtube Ground Ivy Herb medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being dried in vacuo, resulting powder Last medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume significantly Ground reduces, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, and there is very significant society to anticipate Justice and economic implications.
Embodiment
Embodiment 1
By the Longtube Ground Ivy Herb medicinal material of fresh collection, clean, be cut into 1cm section, add the water of 0.5 times of amount of medicinal material weight, stir 15 points Clock, fresh squeezing is taken advantage of, collect and just squeeze concoction, the dregs of a decoction add the water of 5 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 5 Times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain Longtube Ground Ivy Herb concoction.Will be even Money herbal medicine juice is concentrated under reduced pressure, and temperature is set as 65 DEG C.When medicinal extract relative density obtained by concentration is 1.15, vacuum drying is transferred to In case, dried 8 hours in 60 DEG C, 60 mesh sieves are crossed after crushing, pack, 1kg/ bags, add packed antioxidant and drier, vacuum Encapsulation.
Embodiment 2
By the Longtube Ground Ivy Herb medicinal material of fresh collection, clean, be cut into 2cm section, add the water of 1 times of amount of medicinal material weight, stir 30 minutes, Fresh squeezing is taken advantage of, collects and just squeezes concoction, the dregs of a decoction add the water of 5 times of amounts, stir 10min, press extracting juice, and the remaining dregs of a decoction add 3 times The water of amount, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens, obtain Longtube Ground Ivy Herb concoction.Money will be connected Herbal medicine juice is concentrated under reduced pressure, in 65 DEG C dry 6 hours, after crushing cross 60 mesh sieves, pack, 1kg/ bags, add packed antioxidant and Drier, Vacuum Package.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected Within the scope of.

Claims (2)

  1. A kind of 1. fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb, it is characterised in that:Gathered in Longtube Ground Ivy Herb picking time Its herb, clean, be cut into 1 ~ 2cm section, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 minutes, take advantage of fresh squeezing, receive Collection just squeeze concoction, the dregs of a decoction add 1 ~ 5 times amount water, stir 5 ~ 30min, press extracting juice, the remaining dregs of a decoction add 1 ~ 5 times amount Water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens, obtain Longtube Ground Ivy Herb concoction.
  2. A kind of 2. fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb according to claim 1, it is characterised in that: By obtained Longtube Ground Ivy Herb concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density be 1.05 ~ 1.30 medicinal extract, and by its in 40 ~ 70 DEG C vacuum drying 4 ~ 8 hours after crushed 60 ~ 120 mesh sieves, be vacuum-packed, produce Longtube Ground Ivy Herb it is fresh squeeze vacuum drying powder Medicine materical crude slice.
CN201710739055.8A 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb Pending CN107334814A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710739055.8A CN107334814A (en) 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710739055.8A CN107334814A (en) 2017-08-25 2017-08-25 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Longtube Ground Ivy Herb

Publications (1)

Publication Number Publication Date
CN107334814A true CN107334814A (en) 2017-11-10

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Country Status (1)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105213551A (en) * 2015-11-14 2016-01-06 芜湖天成普阳中药科技有限公司 A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof
CN106109543A (en) * 2016-07-24 2016-11-16 徐漫 A kind of Herba Euphorbiae Humifusae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof
CN106109533A (en) * 2016-07-23 2016-11-16 徐自升 A kind of Flos Lonicerae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof
CN106109574A (en) * 2016-07-24 2016-11-16 徐漫 A kind of Herba Scutellariae Barbatae is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof
CN106109596A (en) * 2016-07-23 2016-11-16 徐自升 A kind of Herba Plantaginis is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105213551A (en) * 2015-11-14 2016-01-06 芜湖天成普阳中药科技有限公司 A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof
CN106109533A (en) * 2016-07-23 2016-11-16 徐自升 A kind of Flos Lonicerae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof
CN106109596A (en) * 2016-07-23 2016-11-16 徐自升 A kind of Herba Plantaginis is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof
CN106109543A (en) * 2016-07-24 2016-11-16 徐漫 A kind of Herba Euphorbiae Humifusae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof
CN106109574A (en) * 2016-07-24 2016-11-16 徐漫 A kind of Herba Scutellariae Barbatae is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof

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Application publication date: 20171110