CN108619357A - Chinese yam is fresh to carry spray-dried powders medicine materical crude slice - Google Patents

Chinese yam is fresh to carry spray-dried powders medicine materical crude slice Download PDF

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Publication number
CN108619357A
CN108619357A CN201810733349.4A CN201810733349A CN108619357A CN 108619357 A CN108619357 A CN 108619357A CN 201810733349 A CN201810733349 A CN 201810733349A CN 108619357 A CN108619357 A CN 108619357A
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CN
China
Prior art keywords
fresh
materical crude
medicine materical
crude slice
decoction
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810733349.4A
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Chinese (zh)
Inventor
徐漫
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Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201810733349.4A priority Critical patent/CN108619357A/en
Publication of CN108619357A publication Critical patent/CN108619357A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a kind of " Chinese yam is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that:Yam medicinal material harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, crush, be sieved after be vacuum-packed.The water content of powder decoction pieces is less than 10%.Such prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule etc., is conducive to carry, Clinical practice is convenient.

Description

Chinese yam is fresh to carry spray-dried powders medicine materical crude slice
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Chinese yam medicine materical crude slice.
Background technology
Traditional Chinese medicine Chinese yam is Dioscoreaceae plant Chinese yamDioscotea oppositaThunb. dry rhizome has tonifying spleen Nourishing the stomach, engender liquid and benefic lung, effect of the puckery essence of kidney tonifying.This product is mainly used for spleen eating less, endless diarrhea, and the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, Under band, frequent micturition, abnormal heat is quenched one's thirst the treatments of equal diseases, is a herb common on tcm clinical practice.The processing method of traditional Chinese yam is: It is excavated after winter cauline leaf is withered, cuts root head, cleaned, remove crust and fibrous root, it is dry, it practises and claims " hair yam slice ";Or it removes outer Skin takes advantage of fresh-cut sheet, dry, referred to as " yam slice ";Also there is the loose straight drying Chinese yam of selection, set in clear water, be dipped into without dry The heart, it is bored, both ends are trimmed, are twisted into plank cylindric, are dried, polishing, practises and claims " light yam ".Such medicine materical crude slice volume is big, health Standard deviation is learned, is easy to make moist, is mildew, infested, being unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality is steady Qualitative difference, clinical efficacy be difficult to ensure, patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/ Transportation cost is low, conducive to keeping, carry and easy to use, rapid-action novel Chinese yam medicine materical crude slice, it is imperative.Existing market Chinese yam Medicine materical crude slice, other than traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both drunk with tradition Piece is raw material, and quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;Concentrated granular Water soluble ingredient can only be extracted.
Invention content
The invention discloses a kind of " Chinese yam is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that:In yam medicinal material After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~ The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, Dregs pressing takes juice.Add the water of 5 ~ 10 times of 50 ~ 70 DEG C of weight in the gained dregs of a decoction, stirring at low speed 10 ~ 30 minutes, mistake while hot Filter, the dregs of a decoction are squeezed the juice again, collect concoction.Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, dense It is reduced to the concentrate that relative density is 1.02 ~ 1.10.The concentrate of gained is spray-dried, control dried object water content is 10% Within, it crushes, crosses 60 mesh sieve, be vacuum-packed to get finished product.The clinical general usage amount of this powder decoction pieces is 1 ~ 5g, can both enter soup Agent decoction is taken after mixing it with water, and also can directly be entered in pill, powder, capsule and tablet, to substantially increase the convenience of Clinical practice And compliance, be conducive to the treatment of clinical acute disease.
The present invention solve traditional Chinese yam medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.
Specific embodiment
It after yam medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is scraped off crust, is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, mistake Filter, dregs pressing take juice.The pure water of 8 times of 70 DEG C of weight is added into the above-mentioned dregs of a decoction again, stirring at low speed 30 minutes filters, The dregs of a decoction are squeezed the juice again, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and being concentrated into relative density is 1.05.The concentrate of gained is spray-dried, until water content is 10%, is crushed, 60 mesh sieve is crossed, is vacuum-packed to get finished product.

Claims (2)

1. a kind of Chinese yam is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that:After yam medicinal material harvesting, clean in time, Impurity and the dis-medicinal parts such as silt are removed, crust is cleaned and scrape off in taking advantage of using fresh herb tap water in 12 hours, is cut into 2 ~ 5mm thickness The water of 1 ~ 5 times of 50 ~ 70 DEG C of weight is added in piece, impregnates and constantly stirs 5 ~ 30 minutes, filtering, dregs pressing takes juice;The gained dregs of a decoction In add 50 ~ 70 DEG C of water of 5 ~ 10 times of weight, constantly stir 10 ~ 30 minutes, filter while hot, the dregs of a decoction are squeezed the juice again, are collected Concoction;Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, be concentrated into relative density be 1.02 ~ 1.10;Gained concentrate be spray-dried, control dried object water content be 10% within, crush, cross 60 mesh sieve, vacuum packaging to get Finished product.
2. Chinese yam according to claim 1 is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that:Clinic generally uses Amount is 1 ~ 5g, and such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
CN201810733349.4A 2018-07-06 2018-07-06 Chinese yam is fresh to carry spray-dried powders medicine materical crude slice Pending CN108619357A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810733349.4A CN108619357A (en) 2018-07-06 2018-07-06 Chinese yam is fresh to carry spray-dried powders medicine materical crude slice

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810733349.4A CN108619357A (en) 2018-07-06 2018-07-06 Chinese yam is fresh to carry spray-dried powders medicine materical crude slice

Publications (1)

Publication Number Publication Date
CN108619357A true CN108619357A (en) 2018-10-09

Family

ID=63689702

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810733349.4A Pending CN108619357A (en) 2018-07-06 2018-07-06 Chinese yam is fresh to carry spray-dried powders medicine materical crude slice

Country Status (1)

Country Link
CN (1) CN108619357A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107362182A (en) * 2017-08-25 2017-11-21 徐漫 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of phoenix-tail fern
CN107412303A (en) * 2017-08-25 2017-12-01 芜湖天成普阳中药科技有限公司 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium
CN107432883A (en) * 2017-08-25 2017-12-05 徐漫 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed
CN107582624A (en) * 2017-08-25 2018-01-16 徐自升 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin
CN108186690A (en) * 2018-03-21 2018-06-22 山西省医药与生命科学研究院 A kind of Chinese medicine processing method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107362182A (en) * 2017-08-25 2017-11-21 徐漫 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of phoenix-tail fern
CN107412303A (en) * 2017-08-25 2017-12-01 芜湖天成普阳中药科技有限公司 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium
CN107432883A (en) * 2017-08-25 2017-12-05 徐漫 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lopseed
CN107582624A (en) * 2017-08-25 2018-01-16 徐自升 A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin
CN108186690A (en) * 2018-03-21 2018-06-22 山西省医药与生命科学研究院 A kind of Chinese medicine processing method

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Application publication date: 20181009

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