CN108619249A

CN108619249A - Radix Polygalae is fresh to carry spray-dried granules medicine materical crude slice

Info

Publication number: CN108619249A
Application number: CN201810733374.2A
Authority: CN
Inventors: 徐漫
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-10-09

Abstract

The invention discloses a kind of " Radix Polygalae is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：Radix Polygalae harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, granulation, whole grain, vacuum packaging.The water content of granule pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter in capsule, tablet, is conducive to carry, Clinical practice is convenient.

Description

Radix Polygalae is fresh to carry spray-dried granules medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Radix Polygalae medicine materical crude slice.

Background technology

Chinese medicine polygala root is milk wort Radix PolygalaePolygala tenuifoliaOr ovum leaf Radix Polygalae Willd.Polygala sibiriaL. dry root has the effect of tranquilize the mind and promote the intelligence, restoring normal coordination between heart and kidney, eliminating the phlegm, detumescence.Caused by can be used for breakdown of the normal physiological coordination between the heart and the kidney Insomnia and dreamful sleep, forgetful palpitation with fear, wandering, expectoration is not well, sore swollen toxin, and the treatment of the diseases such as mastosis, is on tcm clinical practice Common a herb.The processing method of traditional Radix Polygalae is：After medicinal material is excavated, fibrous root and silt are removed, is dried, is packaged, storage Fortune.Thus obtained Radix Polygalae medicine materical crude slice volume is big, and hygiene condition is poor, easy to pollute to be unfavorable for taking care of, and storage and transportation cost are high.This Outside, such prepared slice quality stability is poor, and clinical efficacy is difficult to ensure, patient takes inconvenience, works slow.Therefore, one is developed Kind of quality is reliable and stable, storage/transportation is at low cost, conducive to keeping, carry and easy to use, rapid-action novel Radix Polygalae medicine materical crude slice, It is imperative.Existing market Radix Polygalae medicine materical crude slice, other than traditional medicine materical crude slice, also two kinds of shapes of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice Formula, but both using traditional medicine materical crude slice as raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve medicine The problem of material pollutes；Concentrated granular can only extract water soluble ingredient.

Invention content

The invention discloses a kind of " Radix Polygalae is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：It is harvested in Radix Polygalae Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.02 ~ 1.10 concentrate.Gained concentrate leaves and takes 1% ~ 3% spare, remaining spray drying.By the spray powder of collection with it is spare Concentrate mixing granulation, dry to be less than 10% to water content, whole grain is vacuum-packed to get finished product.Finished product medicine materical crude slice ketone containing Radix Polygalae III （C₂₅H₂₈O₁₅）No less than 0.2%.Radix Polygalae granule pieces stable quality, good fluidity, clinical general usage amount is 1 ~ 5g.Such drink Piece can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet, to substantially increase the convenience of Clinical practice And compliance, be conducive to the treatment of clinical acute disease.

The present invention solve traditional Radix Polygalae medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.

Specific embodiment

It after Polygala tenuifolia is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density.It will The concentrate of gained leaves and takes 3% spare, remaining spray drying.Spray powder is collected, mixes pelleting with spare concentrate, 80 It is 10% DEG C to be dried under vacuum to water content, and whole grain is vacuum-packed to get finished product.Radix Polygalae ketone III in finished product medicine materical crude slice（C₂₅H₂₈O₁₅）Contain Amount is 0.3%.

Claims

1. a kind of Radix Polygalae is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：It after Radix Polygalae harvesting, cleans, removes in time The impurity such as silt and dis-medicinal part are added 1 ~ 5 times in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness The water that 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice；5 ~ 10 are added in the gained dregs of a decoction The water of times weight, boils 10 ~ 30 minutes, filters while hot, and the dregs of a decoction are squeezed the juice again, collects concoction；Merge above-mentioned concoction, crosses 60 ~ 100 Mesh sieves, and is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；It is standby that gained concentrate leaves and takes 1% ~ 3% With remaining spray drying；By the spray powder of collection and spare concentrate mixing granulation, drying to water content is whole less than 10% Grain is vacuum-packed to get finished product；Finished product medicine materical crude slice ketone containing Radix Polygalae III（C₂₅H₂₈O₁₅）No less than 0.2%.

2. Radix Polygalae according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet.