CN108619226A

CN108619226A - Pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice

Info

Publication number: CN108619226A
Application number: CN201810733336.7A
Authority: CN
Inventors: 徐漫
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-10-09

Abstract

The invention discloses a kind of " pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that：Pueraria lobata medicinal material harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, crush, be sieved after be vacuum-packed.The water content of powder decoction pieces is less than 10%.Such prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule etc., is conducive to carry, Clinical practice is convenient.

Description

Pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical field, the manufacture field for especially belonging to pueraria lobata medicine materical crude slice is fallen.

Background technology

Chinese medicament kudzu-vine root is legume pueraria lobataPueraria lobata (Willd.) dry root of Ohwi has expelling pathogenic factors from muscles and skin It brings down a fever, promotes the production of body fluid to quench thirst, the effect of promoting eruption, Shengyang Zhixie, clearing and activating the channels and collaterals, relieving alcoholism.It is usually used in fever caused by exogenous pathogens headache, rigid neck and back Bitterly, thirsty, it quenches one's thirst, measles without adequate eruption, hot dysentery, diarrhea, the treatment of dizziness and headache etc. is common a herb on tcm clinical practice. The processing method of traditional pueraria lobata is：After medicinal material is excavated, fresh-cut is taken advantage of into sheet or fritter, dry, packing, storage and transportation.Such medicine materical crude slice Volume is big, and Hygienic Standard is poor, is easy to make moist, is mildew, infested, being unfavorable for taking care of, storage and transportation cost are high.In addition, in this way Prepared slice quality stability it is poor, clinical efficacy is difficult to ensure, patient takes inconvenience, works slow.Therefore, it is steady to develop a kind of quality It is fixed reliable, storage/transportation is at low cost, conducive to keeping, carry and easy to use, rapid-action novel pueraria lobata medicine materical crude slice, it is imperative. Existing market pueraria lobata medicine materical crude slice, other than traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but the two All it is using traditional medicine materical crude slice as raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve medicinal material pollution Problem；Concentrated granular can only extract water soluble ingredient.

Invention content

The invention discloses a kind of " pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice ", are primarily characterized in that：In pueraria lobata medicinal material After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~ The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.02 ~ 1.10 concentrate.The concentrate of gained is spray-dried, control dried object water content is to be crushed within 10%, crosses 60 Mesh sieves, and is vacuum-packed to get finished product.Finished product medicine materical crude slice (C containing Puerarin₂₁H₂₀O₉) it is not less than 4.0%.

The clinical general usage amount of this powder decoction pieces is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter pill, dissipate In agent, capsule and tablet, to substantially increase the convenience and compliance of Clinical practice, be conducive to controlling for clinical acute disease It treats.

The present invention solve traditional kudzuvine root drink piece is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular Piece is more preferable.

Specific embodiment

It after pueraria lobata medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density.It will The concentrate of gained is spray-dried, until water content is 10%, is crushed, and is crossed 60 mesh sieve, is vacuum-packed to get finished product.Finished product medicine materical crude slice contains Puerarin (C₂₁H₂₀O₉) it is 4.5%.

Claims

1. a kind of pueraria lobata is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that：After the harvesting of pueraria lobata medicinal material, clean in time, Impurity and the dis-medicinal part such as silt are removed, in the piece for taking advantage of using fresh herb tap water in 12 hours and cleaning and being cut into 2 ~ 5mm thickness, addition 1 ~ The water of 5 times of 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice；5 are added in the gained dregs of a decoction The water of ~ 10 times of weight is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction；Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, and are concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；Gained concentrate is spray-dried, It is to be crushed within 10% to control dried object water content, crosses 60 mesh sieve, is vacuum-packed to get finished product；Finished product medicine materical crude slice contains Puerarin (C₂₁H₂₀O₉) it is not less than 4.0%.

2. pueraria lobata according to claim 1 is fresh to carry spray-dried powders medicine materical crude slice, it is primarily characterized in that：Clinic generally uses Amount is 1 ~ 5g, and such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.