CN108653371A - Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces - Google Patents

Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces Download PDF

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Publication number
CN108653371A
CN108653371A CN201810733262.7A CN201810733262A CN108653371A CN 108653371 A CN108653371 A CN 108653371A CN 201810733262 A CN201810733262 A CN 201810733262A CN 108653371 A CN108653371 A CN 108653371A
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CN
China
Prior art keywords
radix pseudostellariae
decoction
fresh
water
vacuum drying
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Withdrawn
Application number
CN201810733262.7A
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Chinese (zh)
Inventor
徐事成
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Individual
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Individual
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Priority to CN201810733262.7A priority Critical patent/CN108653371A/en
Publication of CN108653371A publication Critical patent/CN108653371A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of " radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:Radix pseudostellariae harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, after extracting solution is condensed into clear cream, then be dried under vacuum to water content be less than 10%, crush, be sieved after be vacuum-packed.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.

Description

Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical field, the manufacture field for especially belonging to radix pseudostellariae medicine materical crude slice is fallen.
Background technology
Chinese medicine radix pseudostellariae is pinkwort caryophyllaceous ginsengPseudostellaria heterophylla (Miq.)Pax The dried root of ex Pax et Hoffm. has and replenishes qi to invigorate the spleen, promoting production of body fluid and nourishing the lung effect.It is tired that this product is mainly used for spleen deficiency body, Loss of appetite, eak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, the treatment of the diseases such as dryness of the lung dry cough, is most common one on tcm clinical practice Taste Chinese medicine.The processing method of traditional radix pseudostellariae is:Summer cauline leaf is excavated when largely withered, is cleaned, and is removed fibrous root, is set in boiling water It dries after slightly scalding or directly dries, pack, storage and transportation.Thus obtained medicine materical crude slice volume is big, and Hygienic Standard is poor, is easy to make moist, grow It is mould, infested, it is unfavorable for taking care of, storage and transportation cost are high.In addition, such radix pseudostellariae prepared slice quality stability is poor, clinic is treated It imitates and is difficult to ensure, patient takes inconvenience, works slow.Therefore, develop that a kind of stable quality is reliable, storage/transportation is at low cost, sharp It is imperative in keeping, carrying and easy to use, rapid-action novel radix pseudostellariae medicine materical crude slice.Radix pseudostellariae medicine materical crude slice currently on the market, Other than traditional medicine materical crude slice, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but be with traditional medicine materical crude slice both Raw material, quality is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;Concentrated granular can only Extract water soluble ingredient.
Invention content
The invention discloses a kind of " radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:In radix pseudostellariae After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~ The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.15 ~ 1.25 clear cream.The clear cream of gained is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, is crushed, 60 mesh sieve is crossed, Vacuum packaging is to get finished product.The clinical general usage amount of this radix pseudostellariae medicine materical crude slice is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, also can be straight It accesses in pill, powder, capsule and tablet, to substantially increase the convenience and compliance of Clinical practice, is conducive to face The treatment of bed acute disease.
The present invention solve traditional radix pseudostellariae medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular Medicine materical crude slice is more preferable.
Specific embodiment
It after radix pseudostellariae medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.20 to be concentrated into relative density Clear cream.It is 8% that the clear cream of gained is dried under vacuum at 80 DEG C to water content, is crushed, and crosses 60 mesh sieve, vacuum packaging to get at Product.

Claims (2)

1. a kind of radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:After radix pseudostellariae harvesting, clean in time, Impurity and the dis-medicinal part such as silt are removed, in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness, addition 1 ~ The water of 5 times of 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice;5 are added in the gained dregs of a decoction The water of ~ 10 times of weight is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, and are concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, are concentrated into the clear cream that relative density is 1.15 ~ 1.25;The clear cream of gained is existed It is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, crushes, crosses 60 mesh sieve, is vacuum-packed to get finished product.
2. radix pseudostellariae according to claim 1 is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:Clinic generally makes Dosage is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
CN201810733262.7A 2018-07-06 2018-07-06 Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces Withdrawn CN108653371A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810733262.7A CN108653371A (en) 2018-07-06 2018-07-06 Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810733262.7A CN108653371A (en) 2018-07-06 2018-07-06 Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces

Publications (1)

Publication Number Publication Date
CN108653371A true CN108653371A (en) 2018-10-16

Family

ID=63773876

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810733262.7A Withdrawn CN108653371A (en) 2018-07-06 2018-07-06 Radix pseudostellariae is fresh to carry vacuum drying powder decoction pieces

Country Status (1)

Country Link
CN (1) CN108653371A (en)

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Application publication date: 20181016

WW01 Invention patent application withdrawn after publication