CN108635415A

CN108635415A - The Chinese bulbul is fresh to carry spray-dried granules medicine materical crude slice

Info

Publication number: CN108635415A
Application number: CN201810733172.8A
Authority: CN
Inventors: 徐自升
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-06
Filing date: 2018-07-06
Publication date: 2018-10-12

Abstract

The invention discloses a kind of " Chinese bulbul is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：The Chinese bulbul harvest after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, extracting solution concentrate after be spray-dried, granulation, whole grain, vacuum packaging.The water content of granule pieces is less than 10%.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter in capsule, tablet, is conducive to carry, Clinical practice is convenient.

Description

The Chinese bulbul is fresh to carry spray-dried granules medicine materical crude slice

Technical field

The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of Chinese bulbul medicine materical crude slice.

Background technology

The Chinese medicine Chinese bulbul is the ranunculaceae plant Chinese bulbulPulsatilla chinensis（Bge.）The dry root of Regel, With clearing heat and detoxicating, the effect of removing heat from the blood and relieve diarrhea.This product is mainly used for toxic-heat and blood stasis, and the treatment under pruritus vulvae band is on tcm clinical practice Common a herb.The processing method of traditional Chinese bulbul is：After medicinal material is excavated, silt is removed, it is dry, it is packaged, storage and transportation.It arrives After medicine materical crude slice factory, then washs, softens, is sliced, dries, packs.Such medicine materical crude slice volume is big, and hygiene condition is poor, is easy to make moist, grow It is mould, it is unfavorable for taking care of, storage and transportation cost are high.In addition, such prepared slice quality stability is poor, clinical efficacy is difficult to ensure, Patient takes inconvenience, works slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping, carry It is imperative with easy to use, rapid-action novel Chinese bulbul medicine materical crude slice.Existing market Chinese bulbul medicine materical crude slice, in addition to traditional medicine materical crude slice it Outside, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality determines In the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes；Concentrated granular can only extract it is water-soluble at Part.

Invention content

The invention discloses a kind of " Chinese bulbul is fresh to carry spray-dried granules medicine materical crude slice ", are primarily characterized in that：In the Chinese bulbul After harvesting, clean in time, removal impurity and the dis-medicinal part such as silt, in taken advantage of in 24 hours using fresh herb tap water clean and be cut into 2 ~ The piece of 5mm thickness.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, Dregs pressing takes juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is 1.02 ~ 1.10 concentrate.Gained concentrate leaves and takes 1% ~ 3% spare, remaining spray drying.By the spray powder of collection with it is spare Concentrate mixing granulation, dry to be less than 10% to water content, whole grain is vacuum-packed to get finished product.Finished product medicine materical crude slice soap containing the Chinese bulbul Glycosides B₄（C₅₉H₉₆O₂₆）No less than 5.0%.Chinese bulbul granule pieces stable quality, good fluidity, clinical general usage amount is 1 ~ 5g. Such medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet, to substantially increase Clinical practice Convenience and compliance are conducive to the treatment of clinical acute disease.

The present invention solve traditional Chinese bulbul medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, The shortcomings such as the poor, unstable quality of hygiene condition, due to being to take advantage of fresh extraction, quality is than ultramicro grinding medicine materical crude slice and concentrated granular Medicine materical crude slice is more preferable.

Specific embodiment

It after Chinese bulbul medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours certainly Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, the dregs of a decoction Press extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again It is secondary to squeeze the juice, collect concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature is to be set as 70 DEG C, and it is 1.05 to be concentrated into relative density. The concentrate of gained is left and taken into 3% spare, remaining spray drying.Spray powder is collected, pelleting is mixed with spare concentrate, It is 10% that 80 DEG C, which are dried under vacuum to water content, and whole grain is vacuum-packed to get finished product.Pulchinenoside B in finished product medicine materical crude slice₄ （C₅₉H₉₆O₂₆）Content is 5.5%.

Claims

1. a kind of Chinese bulbul is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：After the Chinese bulbul harvests, clean in time, Impurity and the dis-medicinal part such as silt are removed, in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness, addition 1 ~ The water of 5 times of 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice；5 are added in the gained dregs of a decoction The water of ~ 10 times of weight is boiled 10 ~ 30 minutes, is filtered while hot, and the dregs of a decoction are squeezed the juice again, collects concoction；Merge above-mentioned concoction, cross 60 ~ 100 mesh sieve, and are concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, and it is 1.02 ~ 1.10 to be concentrated into relative density；Gained concentrate leaves and takes 1% ~ 3% It is spare, remaining spray drying；By the spray powder of collection and spare concentrate mixing granulation, drying to water content is whole less than 10% Grain is vacuum-packed to get finished product；Finished product medicine materical crude slice B containing pulchinenoside₄（C₅₉H₉₆O₂₆）No less than 5.0%.

2. the Chinese bulbul according to claim 1 is fresh to carry spray-dried granules medicine materical crude slice, it is primarily characterized in that：Clinic generally makes Dosage is 1 ~ 5g, this medicine materical crude slice can both enter decoction decoction, take after mixing it with water, and also can directly enter in capsule and tablet.