CN108619259A - Cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces - Google Patents
Cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces Download PDFInfo
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- CN108619259A CN108619259A CN201810733263.1A CN201810733263A CN108619259A CN 108619259 A CN108619259 A CN 108619259A CN 201810733263 A CN201810733263 A CN 201810733263A CN 108619259 A CN108619259 A CN 108619259A
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- Prior art keywords
- decoction
- fresh
- cimicifugae foetidae
- water
- vacuum drying
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of " cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:Cimicifugae foetidae harvesting after, take advantage of it is fresh wash, be sliced, squeezing the juice, extracting, after extracting solution is condensed into clear cream, then be dried under vacuum to water content be less than 10%, crush, be sieved after be vacuum-packed.This prepared slice quality is stablized, and can both enter decoction decocting, can also directly enter pill, powder, tablet, capsule, is conducive to carry, Clinical practice is convenient.
Description
Technical field
The invention belongs to prepared slices of Chinese crude drugs technical fields, especially belong to the manufacture field of cimicifugae foetidae medicine materical crude slice.
Background technology
Chinese medicine cimicifugae foetidae is ranunculaceae plant C.heracleifoliaCimicifuga heracleifoliaKom., Cimicifuga DahuricaCimicifuga dahurica (Turcz.)Or cimicifugae foetidae Maxim.Cimicifuga foetidaL. dry rhizome, has
Promoting eruption is delivered, it is clearing heat and detoxicating, rise the effect of lifting yang-energy.This product is mainly used for headache due to pathogenic wind-heat, dentalgia, aphtha, abscess of throat, measles
Impermeable, sun poison macular eruption, rectal prolapse, the treatment of the diseases such as prolapse of uterus is a herb common on tcm clinical practice.Traditional cimicifugae foetidae adds
Work method is:Autumn excavates, and removes silt and burns or remove fibrous root when solarization is done to fibrous root, dry, is packaged, storage and transportation.To medicine materical crude slice
After factory, then washs, softens, is sliced, dries, packs.Medicine materical crude slice volume made from this method is big, and Hygienic Standard is poor, is easy to make moist, grow
It is mould, it is unfavorable for taking care of, storage and transportation cost are high.In addition, such cimicifugae foetidae prepared slice quality stability is poor, clinical efficacy is difficult to protect
Barrier, patient take inconvenience, work slow.Therefore, develop a kind of stable quality is reliable, storage/transportation is at low cost, be conducive to keeping,
Carrying and easy to use, rapid-action novel cimicifugae foetidae medicine materical crude slice, it is imperative.Cimicifugae foetidae medicine materical crude slice currently on the market, in addition to tradition is drunk
Except piece, also two kinds of forms of Ultramicro-powder medicine materical crude slice and concentrated granular medicine materical crude slice, but both using traditional medicine materical crude slice as raw material, quality
It is decided by the quality of traditional medicine materical crude slice, and ultramicro decoction piece cannot solve the problems, such as that medicinal material pollutes;Concentrated granular can only extract water-soluble
Property ingredient.
Invention content
The invention discloses a kind of " cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces ", are primarily characterized in that:It is harvested in cimicifugae foetidae
Afterwards, it cleans in time, removal impurity and the dis-medicinal part such as silt, cleans in taking advantage of using fresh herb tap water in 24 hours and be cut into 2 ~ 5mm
Thick piece.The piece that this cuts is added in the water of 1 ~ 5 times of 50 ~ 70 DEG C of weight, impregnate and is constantly stirred 5 ~ 30 minutes, filtering, medicine
Slag presses extracting juice.The water that 5 ~ 10 times of weight is added in the gained dregs of a decoction is boiled 10 ~ 30 minutes, is filtered while hot, the dregs of a decoction squeeze again
Juice collects concoction.Merge above-mentioned concoction, crosses 60 ~ 100 mesh sieve, be concentrated under reduced pressure, temperature is 50 ~ 75 DEG C, and being concentrated into relative density is
1.15 ~ 1.25 clear cream.The clear cream of gained is dried under vacuum to water content at 60 ~ 80 DEG C and is less than 10%, is crushed, 60 mesh sieve is crossed,
Vacuum packaging is to get finished product.Finished product contains isoferulic acid(C10H10O4)No less than 0.20%.The clinical general usage amount of this cimicifugae foetidae medicine materical crude slice
For 1 ~ 5g, it can both enter decoction decoction, take after mixing it with water, also can directly enter in pill, powder, capsule and tablet, to substantially increase
The convenience and compliance of Clinical practice, are conducive to the treatment of clinical acute disease.
The present invention solve traditional cimicifugae foetidae medicine materical crude slice is bulky, carrying cost is high, be unfavorable for keeping, easily mildew it is infested, defend
The shortcomings such as the poor, unstable quality of raw condition, due to being to take advantage of fresh extraction, quality is drunk than ultramicro grinding medicine materical crude slice and concentrated granular
Piece is more preferable.
Specific embodiment
It after cimicifugae foetidae medicinal material is harvested, cleans, removes impurity and the dis-medicinal parts such as silt, using fresh herb is taken advantage of in 6 hours originally
Water is cleaned, and is cut into the piece of 3mm thickness.This piece is added to 70 DEG C of pure water of 5 times of weight, is stirred 30 minutes, filtering, dregs of a decoction pressure
Extracting juice.The pure water for adding 8 times of weight into the above-mentioned dregs of a decoction again is boiled 20 minutes and is extracted, filters while hot, the dregs of a decoction are again
It squeezes the juice, collects concoction.Merge above-mentioned concoction, be concentrated under reduced pressure, temperature be set as 70 DEG C, be concentrated into relative density be 1.20 it is clear
Cream.It is 8% that the clear cream of gained is dried under vacuum to water content at 80 DEG C, is crushed, and crosses 60 mesh sieve, is vacuum-packed to get finished product.
Finished product contains isoferulic acid(C10H10O4)No less than 0.20%.
Claims (2)
1. a kind of cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:It after cimicifugae foetidae harvesting, cleans, removes in time
The impurity such as silt and dis-medicinal part are added 1 ~ 5 times in the piece for taking advantage of using fresh herb tap water in 24 hours and cleaning and being cut into 2 ~ 5mm thickness
The water that 50 ~ 70 DEG C of weight is impregnated and is constantly stirred 5 ~ 30 minutes, and filtering, dregs pressing takes juice;5 ~ 10 are added in the gained dregs of a decoction
The water of times weight, boils 10 ~ 30 minutes, filters while hot, and the dregs of a decoction are squeezed the juice again, collects concoction;Merge above-mentioned concoction, crosses 60 ~ 100
Mesh sieves, and is concentrated under reduced pressure, and temperature is 50 ~ 75 DEG C, is concentrated into the clear cream that relative density is 1.15 ~ 1.25;By the clear cream of gained 60 ~
It is dried under vacuum to water content at 80 DEG C and is less than 10%, crushes, crosses 60 mesh sieve, is vacuum-packed to get finished product;Finished product contains isoferulic acid
(C10H10O4)No less than 0.20%.
2. cimicifugae foetidae according to claim 1 is fresh to carry vacuum drying powder decoction pieces, it is primarily characterized in that:Clinic generally uses
Amount is 1 ~ 5g, can both enter decoction decoction, take after mixing it with water, and also can directly enter in pill, powder, capsule and tablet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733263.1A CN108619259A (en) | 2018-07-06 | 2018-07-06 | Cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810733263.1A CN108619259A (en) | 2018-07-06 | 2018-07-06 | Cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces |
Publications (1)
Publication Number | Publication Date |
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CN108619259A true CN108619259A (en) | 2018-10-09 |
Family
ID=63688796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810733263.1A Withdrawn CN108619259A (en) | 2018-07-06 | 2018-07-06 | Cimicifugae foetidae is fresh to carry vacuum drying powder decoction pieces |
Country Status (1)
Country | Link |
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CN (1) | CN108619259A (en) |
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2018
- 2018-07-06 CN CN201810733263.1A patent/CN108619259A/en not_active Withdrawn
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Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181009 |
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WW01 | Invention patent application withdrawn after publication |