CN103097386A - 脂质化免疫反应调节剂化合物的组合物、制剂及方法 - Google Patents

脂质化免疫反应调节剂化合物的组合物、制剂及方法 Download PDF

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CN103097386A
CN103097386A CN2011800442410A CN201180044241A CN103097386A CN 103097386 A CN103097386 A CN 103097386A CN 2011800442410 A CN2011800442410 A CN 2011800442410A CN 201180044241 A CN201180044241 A CN 201180044241A CN 103097386 A CN103097386 A CN 103097386A
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compound
butyl
antigen
pharmaceutical composition
formula
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保罗·D·怀特曼
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3M Innovative Properties Co
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3M Innovative Properties Co
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Priority to CN201510694994.6A priority Critical patent/CN105294684B/zh
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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CN2011800442410A 2010-08-17 2011-08-16 脂质化免疫反应调节剂化合物的组合物、制剂及方法 Pending CN103097386A (zh)

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US37451210P 2010-08-17 2010-08-17
US61/374,512 2010-08-17
PCT/US2011/047901 WO2012024284A1 (en) 2010-08-17 2011-08-16 Lipidated immune response modifier compound compositions, formulations, and methods

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US (9) US9242980B2 (enExample)
EP (2) EP2606047B1 (enExample)
JP (5) JP2013534248A (enExample)
CN (2) CN103097386A (enExample)
AU (1) AU2011292146B2 (enExample)
BR (1) BR112013003772A2 (enExample)
CA (2) CA3021114C (enExample)
CY (1) CY1118815T1 (enExample)
DK (1) DK2606047T3 (enExample)
ES (2) ES2943385T3 (enExample)
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MX (1) MX359517B (enExample)
PL (1) PL2606047T3 (enExample)
PT (1) PT2606047T (enExample)
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WO (1) WO2012024284A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
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CN105873587A (zh) * 2013-11-05 2016-08-17 3M创新有限公司 基于芝麻油的注射配制品
CN107106545A (zh) * 2014-08-01 2017-08-29 3M创新有限公司 用于治疗肿瘤的方法和治疗组合
CN114585621A (zh) * 2019-02-01 2022-06-03 康威(广州)生物科技有限公司 咪唑并喹啉胺衍生物、及其药物组合物和应用

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WO2014201245A1 (en) 2013-06-12 2014-12-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Tlr-9 agonist with tlr-7 and/or tlr-8 agonist for treating tumors
GB201321242D0 (en) 2013-12-02 2014-01-15 Immune Targeting Systems Its Ltd Immunogenic compound
US9718706B2 (en) 2014-06-03 2017-08-01 Sensor Electronic Technology, Inc. Ultraviolet transparent enclosure
WO2016183371A1 (en) 2015-05-13 2016-11-17 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for the treatment or prevention of ischemic tissue damage
CN108289858A (zh) 2015-06-30 2018-07-17 宾夕法尼亚州立大学托管会 用于治疗肿瘤性皮肤疾病的瑞喹莫特局部可注射组合物
EP3344623B1 (en) 2015-08-31 2021-02-17 3M Innovative Properties Company Imidazo[4,5-c]ring compounds containing substituted guanidine groups
WO2017040233A1 (en) 2015-08-31 2017-03-09 3M Innovative Properties Company GUANIDINE SUBSTITUTED IMIDAZO[4,5-c] RING COMPOUNDS
DK3355933T3 (da) 2015-09-29 2020-07-20 Sumitomo Dainippon Pharma Co Ltd Adeninkonjugatforbindelser og deres anvendelse som vaccineadjuvanser
TWI718188B (zh) 2015-10-07 2021-02-11 日商大日本住友製藥股份有限公司 嘧啶化合物
CA3008055A1 (en) 2015-12-14 2017-06-22 Glaxosmithkline Biologicals S.A. Pegylated imidazoquinolines as tlr7 and tlr8 agonists
EP3458028A1 (en) * 2016-05-16 2019-03-27 Infectious Disease Research Institute Pegylated liposomes and methods of use
BR112018073690B1 (pt) 2016-05-16 2022-05-24 Infectious Disease Research Institute Formulação contendo agonista de tlr e métodos de uso
TW201840316A (zh) * 2017-01-12 2018-11-16 美商麥迪紐有限責任公司 Ｔｏｌｌ樣受體７／８激動劑之安全性和藥物活性
WO2018160552A1 (en) 2017-03-01 2018-09-07 3M Innovative Properties Company IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING GUANIDINE SUBSTITUTED BENZAMIDE GROUPS
US11032816B2 (en) * 2017-08-10 2021-06-08 Qualcomm Incorporated Techniques and apparatuses for variable timing adjustment granularity
CN111511740B (zh) 2017-12-20 2023-05-16 3M创新有限公司 用作免疫应答调节剂的带有支链连接基团的酰胺取代的咪唑并[4,5-c]喹啉化合物
CA3092545A1 (en) 2018-02-28 2019-09-06 3M Innovative Properties Company Substituted imidazo[4,5-c]quinoline compounds with an n-1 branched group
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