CY1118815T1 - Συνθεσεις, φαρμακοτεχνικες μορφες και μεθοδοι λιπιδιωμενων ενωσεων τροποποιητων ανοσολογικης απαντησης - Google Patents

Συνθεσεις, φαρμακοτεχνικες μορφες και μεθοδοι λιπιδιωμενων ενωσεων τροποποιητων ανοσολογικης απαντησης

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Publication number
CY1118815T1
CY1118815T1 CY20171100425T CY171100425T CY1118815T1 CY 1118815 T1 CY1118815 T1 CY 1118815T1 CY 20171100425 T CY20171100425 T CY 20171100425T CY 171100425 T CY171100425 T CY 171100425T CY 1118815 T1 CY1118815 T1 CY 1118815T1
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CY
Cyprus
Prior art keywords
immune response
compositions
methods
pharmaceutical forms
modified immune
Prior art date
Application number
CY20171100425T
Other languages
English (en)
Inventor
Paul D Wightman
Original Assignee
3M Innovative Properties Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Company filed Critical 3M Innovative Properties Company
Publication of CY1118815T1 publication Critical patent/CY1118815T1/el

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
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    • C12N2760/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

Η ένωση Ν-(4-{[4-αμινο-2-βουτυλο-1Η-ιμιδαζο[4,5-c]κουινολιν-1-υλ]οξυ} βουτυλ)δεκαοκταναμίδιο είναι μια χρήσιμη φαρμακευτική ένωση για την ενίσχυση της ανοσολογικής απάντησης και μπορεί να χρησιμοποιηθεί, για παράδειγμα, ως ένα ανοσοενισχυτικό εμβολίου και ως θεραπεία του καρκίνου.
CY20171100425T 2010-08-17 2017-04-10 Συνθεσεις, φαρμακοτεχνικες μορφες και μεθοδοι λιπιδιωμενων ενωσεων τροποποιητων ανοσολογικης απαντησης CY1118815T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37451210P 2010-08-17 2010-08-17
PCT/US2011/047901 WO2012024284A1 (en) 2010-08-17 2011-08-16 Lipidated immune response modifier compound compositions, formulations, and methods

Publications (1)

Publication Number Publication Date
CY1118815T1 true CY1118815T1 (el) 2018-01-10

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CY20171100425T CY1118815T1 (el) 2010-08-17 2017-04-10 Συνθεσεις, φαρμακοτεχνικες μορφες και μεθοδοι λιπιδιωμενων ενωσεων τροποποιητων ανοσολογικης απαντησης

Country Status (20)

Country Link
US (9) US9242980B2 (el)
EP (2) EP3222621B1 (el)
JP (5) JP2013534248A (el)
CN (2) CN103097386A (el)
AU (1) AU2011292146B2 (el)
BR (1) BR112013003772A2 (el)
CA (2) CA3021114C (el)
CY (1) CY1118815T1 (el)
DK (1) DK2606047T3 (el)
ES (2) ES2943385T3 (el)
HK (1) HK1217942A1 (el)
HR (1) HRP20170433T1 (el)
HU (1) HUE033901T2 (el)
LT (1) LT2606047T (el)
MX (1) MX359517B (el)
PL (1) PL2606047T3 (el)
PT (1) PT2606047T (el)
RS (1) RS55819B1 (el)
SI (1) SI2606047T1 (el)
WO (1) WO2012024284A1 (el)

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