CN105294684A - 脂质化免疫反应调节剂化合物的组合物、制剂及方法 - Google Patents
脂质化免疫反应调节剂化合物的组合物、制剂及方法 Download PDFInfo
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Abstract
Description
免疫材料 | 小鼠的数目 | 平均肿瘤尺寸(s.d.) |
PBS | 7 | 10.21(4.34) |
卵清蛋白 | 8 | 10.18(8.95) |
卵清蛋白+实例1中的化合物 | 8 | 0.99(0.81) |
免疫群组 | IgG1端点 | IgG2a端点 |
HA 1μg | 2.5E4 | 3.3E2 |
HA 5μg | 6.7E4 | 1.0E3 |
HA 15μg | 6.7E4 | 2.5E3 |
HA 1μg+实例1中的化合物 | 1.7E7 | 3.3E6 |
HA 5μg+实例1中的化合物 | 1.4E7 | 2.5E7 |
HA 15μg+实例1中的化合物 | 1.1E7 | 1.0E8 |
Claims (14)
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US37451210P | 2010-08-17 | 2010-08-17 | |
US61/374,512 | 2010-08-17 | ||
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CN1894244A (zh) * | 2000-12-08 | 2007-01-10 | 3M创新有限公司 | 芳基醚取代的咪唑并喹啉化合物 |
WO2004032829A2 (en) * | 2002-08-15 | 2004-04-22 | 3M Innovative Properties Company | Immunostimulatory compositions and methods of stimulating an immune response |
WO2005018555A2 (en) * | 2003-08-14 | 2005-03-03 | 3M Innovative Properties Company | Lipid-modified immune response modifiers |
WO2005051317A2 (en) * | 2003-11-25 | 2005-06-09 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
WO2006028962A2 (en) * | 2004-09-02 | 2006-03-16 | 3M Innovative Properties Company | 1-alkoxy 1h-imidazo ring systems and methods |
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嵇汝运等: "《药学大词典》", 30 September 2006 * |
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