CN102016036B - 经修饰的RNAi多核苷酸及其用途 - Google Patents

经修饰的RNAi多核苷酸及其用途 Download PDF

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Publication number
CN102016036B
CN102016036B CN200980112313.3A CN200980112313A CN102016036B CN 102016036 B CN102016036 B CN 102016036B CN 200980112313 A CN200980112313 A CN 200980112313A CN 102016036 B CN102016036 B CN 102016036B
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dsrna
nucleotide
sense strand
modified
strand
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CN102016036A (zh
Inventor
帕梅拉·A·帕夫科
乔安妮·卡门斯
托德·M·伍尔夫
威廉·萨洛蒙
阿纳斯塔西娅·赫沃罗娃
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Phio Pharmaceuticals Corp
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RXi Pharmaceuticals Corp
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CN200980112313.3A 2008-02-11 2009-02-11 经修饰的RNAi多核苷酸及其用途 Expired - Fee Related CN102016036B (zh)

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US6533508P 2008-02-11 2008-02-11
US61/065,335 2008-02-11
PCT/US2009/000852 WO2009102427A2 (en) 2008-02-11 2009-02-11 Modified rnai polynucleotides and uses thereof

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US (2) US10131904B2 (https=)
EP (2) EP2247729B1 (https=)
JP (3) JP5697993B2 (https=)
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